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Donna and Sam Van Why are adjusting to a new lifestyle. Several years ago, after signs of failing short-term memory, doctors informed the couple that Donna was dealing with a neurocognitive disorder that’s possibly Alzheimers. Sam is now her primary caregiver.“I have a long ways to go in getting my cooking up to where Donna was before,” Van Why said.According to the Alzheimer’s Association, more than 5 million Americans are living with Alzheimer’s disease. Director of Scientific Engagement Rebecca Edelmayer says the disease causes progressive memory and function loss due to nerve cell death that happens in the brain. This leads to stages of dementia.“Dementia are those symptoms that people are experiencing outwardly," Dr. Edelmayer said. "So this could be changes in their memory or their thinking. It could also be changing in their personality or some of their behaviors. Like they may have issues with depression, or agitation, or even sleep disturbances.”Currently, there’s no treatment for Alzheimer’s, but research is moving at a fast pace and Van Why is always thrilled to hear about any new discoveries.“We may not be to the point of the solved vaccine for Alzheimer’s, but these steps are tremendous,” Van Why said.Aside from treatment, preventing the disease in the first place would be substantial progress and getting a yearly flu shot could be an answer.“New research presented at the Alzheimer’s Association International Conference suggests that flu and pneumonia vaccines may be associated with a lower risk of Alzheimer’s,” Dr. Edelmayer said.Fourth-year medical student Albert Amran made the discovery when pulling medical history of nearly 40,000 people in a national database. He says he and his colleagues at McGovern Medical School at UT Health in Houston looked at patients' charts focusing on drug history to see if anything could be repurposed to reduce the risk of Alzheimer’s disease. The influenza vaccination popped out.“What we’re thinking is happening that as people get older the people who gets shots essentially are keeping their immune systems in shape,” Amran said.However, it should be noted that this research isn’t conclusive. Amran says it’s all very new and needs to be observed in a clinical study. Edelmayer suggests the risk reduction for Alzheimer’s could even be from a completely different factor.“It’s very possible that these are indirect effects," Dr. Edelmayer said. "That people who are getting vaccinated also take care of their health in other ways. And things could really add to a lower risk of Alzheimer’s and other dementias.”Amran says the next step is seeing if these findings can be confirmed in different populations. In the meantime, families feeling the effects of Alzheimer’s are doing what they can to help the ones they love while waiting for a treatment or cure.“I am trying my best to stay in the house or with Sam. I’m lucky I got him,” Donna Van Why said. 2944
Each winter, many people wonder whether its worth getting a flu shot while health officials repeatedly warn against not getting one.Now a new study sheds light on the benefit of doing so. Even when the flu shot is just 20% effective it can still reduce US doctor visits due to illness by an estimated 20 million in a single year, the new report published in the scientific journal PNAS (Proceedings of the National Academy of Sciences of the United States) finds.In addition, vaccination also can prevent thousands of hospitalizations and deaths, the study authors estimated based on the average vaccination coverage rate in the United States."Getting vaccinated against influenza is beneficial to the individual and to the community even when the vaccine is of relatively low efficacy," said Burton H. Singer, co-author of the study and an adjunct professor for the Emerging Pathogens Institute at University of Florida in Gainesville.Caused by viruses, flu is a contagious respiratory illness with mild to severe symptoms that can sometimes lead to death. The flu virus evolves rapidly and new viruses circulate in different parts of the world, so each year scientists must reformulate the vaccine. Add to that an imperfect manufacturing process and even a 'good match' formulation may not be as effective as scientists would like.In fact, the Centers for Disease Control and Prevention estimated just 36% effectiveness for the 2017-18 seasonal vaccine as of February 3. (The season ends in May.)For the new study, Singer and his colleagues created a mathematical model of flu transmission and vaccination to evaluate how much illness is prevented by even a very low effectiveness flu vaccine. The research team found that at the average rate of US coverage even a poor vaccine would prevent a significant amount of illnesses, hospitalizations and deaths.For example, at just 43% coverage (the average rate of Americans who received a flu shot for the years 2012 through 2017), a vaccine with just 20% effectiveness could avert more than 20 million infections or illnesses as compared to not getting the vaccine. In addition, 129,000 hospitalizations and 61,000 deaths could be prevented.Based on the model, if more people got a flu shot, say half of the US population, the same 20% effective flu shot would prevent an additional 3.63 million infections, 21,987 hospitalizations and 8,479 deaths."When a vaccine is fully effective on 50% or more of the people who are vaccinated, you need to primarily focus on vaccinating young children," said Singer. The reason? Children are still building immunity and they pass germs around at school."As efficacy of the vaccine decreases, it becomes increasingly important for the elderly to be vaccinated in addition to young children," said Singer, since the elderly are more likely to develop complications from the flu, such as pneumonia, which can be deadly.The CDC reported a total of 160 flu-related deaths in children and 30,064 flu-related hospitalizations overall?between October 1, 2017 and April 21, 2018. The highest rate of hospitalization occurred among adults 65 years old and older.Richard Webby, a flu scientist who is part of the World Health Organization's advisory board and a member of St. Jude Children's Research Hospital's Department of Infectious Diseases, said "effectiveness estimates go up and down based on a number of factors including match of vaccine and circulating strain and probably other factors we don't fully understand.""The take home message from the past few seasons is that there is much room for improvement," said Webby, who was not involved in the research.Still, more people, particularly the elderly, need to get vaccinated even when the vaccine effectiveness is lower than hoped, Webby said: "This study suggests that even with a less than optimal vaccine there is still much public health benefit that can be achieved if these are used properly and widely." 3992

DOVER, Del. (AP) — Erik Moses has been named president of Nashville Superspeedway. He's the first Black man to hold that title at any NASCAR track. Moses most recently served as president of the XFL's DC Defenders. Prior to working for the XFL, Moses served as CEO of the DC Sports & Entertainment Commission, Director of D.C. Department of Small & Local Business Development, and Senior Vice President at Events DC.He now leads the charge of the scheduled Nashville reboot in 2021. Moses says he was "hired to do a job, not because of what color I am." 570
EL CAJON, Calif. (KGTV) - A possible vehicle break-in led to a deadly shooting in the East County early Sunday.El Cajon Police received a report of shots fired just after 1 a.m. near West Chase Avenue in El Cajon. Police said a homeowner was woken up by the sound of his dogs barking in the 1100 block of Mona Place and looked outside to see someone trying to break into his vehicle.The homeowner retrieved his handgun and went outside to confront the 32-year-old suspect, police said.A confrontation between the two occurred and the homeowner shot at the suspect multiple times, police said, striking him at least once.The suspect then took off in his own vehicle and crashed into the driveway of a nearby home in the 1000 block of West Chase Ave. Officers arrived to find him dead of a gunshot wound.Police have not released the identity of the homeowner or suspect. The homeowner is cooperating with officers. It's not yet clear if that person will face any criminal charges as a result of the shooting. 1054
During this pandemic, people aren’t interacting like they used to.Many schools have moved online, restaurants have moved outdoors, and public transportation is spacing out its seating.With less face-to-face interaction in the real world, scientists are now turning to artificial intelligence.“Robots are our friends,” said Jeffrey Krichmar, Ph.D., a professor of cognitive sciences at the University of California, Irvine (UCI).Recently, Krichmar’s team started testing socially assistive robots with the goal of helping people perform household chores, accomplish health care tasks and even offer them emotional support.“That could be very helpful if a person is impaired and can’t get help in the home because they’re locked down or quarantined,” he said.Krichmar says there’s a lot of societal benefits with this technology, too, like helping people cope with their feelings during isolation.“If I’m not able to get to you, but you have a robot there I can log on through the robot, have a conversation with you and then maybe do tasks around the house with a robot,” he said.Many of UCI’s robotic projects involve the Toyota Human Support Robot.“When you think about the social interaction, I think we’re all feeling this right now,” said Douglas Moore, Toyota’s director of technology for human support.Moore says working with UCI during the COVID-19 crisis could help many people both physically and emotionally.“One of the silver linings that I think we’re going to get out of this pandemic that we’re currently in, we’re going to develop a little bit more sympathy and empathy for the communities that idea with this on a day-to-day basis that have no real light at the end of the tunnel,” he said.Project leaders hope to get more of these robots in people’s homes“The ones that we’re doing with Toyota, they’re not commercially available yet and the ones that are a little pricey,” Krichmar said. “They’re like an expensive luxury car right now.”Krichmar believes more interest could help lower the cost of these robots and that more attention could create future innovation.“This pandemic is our Fukushima moment in a way,” Krichmar said of the COVID-19 crisis.“If this drags on a lot longer, it might be actually useful for this particular crisis,” he said. “But I’m almost thinking like the next crisis down the road.” 2338
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