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A team at the University of Kentucky is researching a possible treatment for COVID-19 and key helpers are three alpacas; Big Boy, Blue Eyes and Emperor.“It’s a powerful technology that we have at UK (University of Kentucky) and it’s something that hopefully we can develop some therapeutics with,” said Wally Whiteheart, a professor in the Department of Molecular & Cellular Biochemistry.Alpacas, along with llamas and camels, make a special kind of antibody called a nanobody. Nanobodies can be useful in cancer research and for other diseases. Researchers, led by Whiteheart and fellow professor Lou Hersh, are working with a nearby ranch to see what impact alpacas could have on COVID-19.“We, in a sense vaccinate them, and this case with viral proteins, and we make nanobodies to those viral proteins,” explained Whiteheart. “We can then go and purify and identify the nanobodies that bind to the virus and then test them to see if they can inhibit viral infection.”Making the nanobodies is just the first step. The team will see which, if any, can block virus infection and those candidates could move on to clinical trials.There’s still a lot of research and testing to go, and also still a lot of hope.“The cool thing which we’re exploring now is the fact that you might be able to use them as a nasal spray and this actually gets them to the place where the virus is affecting lung tissue,” said Whiteheart.This isn’t the first time the trio of alpacas has helped medical research. Big Boy, Blue Eyes and Emperor have contributed to the university’s nanobody research for more than three years. In that time, they have helped researchers generate more than 50 nanobodies to target proteins involved in a variety of human diseases including cancer, diabetes and neurological disorders.This story was originally reported by Alex Valverde on LEX18.com. 1869
A military jet went down at Lake Havasu Airport on Tuesday morning.According to the United States Air Force, an F-16C aircraft assigned to the 56th Fighter Wing at Luke Air Force Base in Glendale, Arizona diverted and attempted to land at the Lake Havasu Airport around 10:30 a.m. local time.Lake Havasu Fire said the pilot of the plane was able to eject and is expected to be okay. The incident occurred during a routine training exercise. It is unclear what type of plane was involved in the incident or where the pilot is based.Lake Havasu Airport is located about three and a half hours northwest of Phoenix near the state border with California. 668
A new report from the CDC and Rhode Island shows COVID-19 rates below one percent in childcare facilities with young children this summer. They also found a low rate of secondary transmission among these facilities, with 15 percent of coronavirus cases resulting in transmission to at least one other person.“The critical thing here is to build the confidence of teachers, the confidence of parents,” said Dr. Robert Redfield, Director of the Centers for Disease Control and Prevention. “This study provides data, that when things are done with vigilance in partnership with the public health community, you can, in fact, in a complex situation like child care ... you can reopen child care" and have low rates of secondary transmission. The study tracked coronavirus cases at childcare facilities in Rhode Island this summer. On June 1, the state was seeing a decline in coronavirus cases and hospitalizations, and allowed childcare programs to re-open after a 3-month closure.In order to reopen, the facility had to submit a plan to the state for approval that included reduced enrollment, a cohort of no more than 20 people including kids and staff, universal use of masks for adults, and daily symptom screening of adults and kids.Roughly 75 percent of licensed center and home-based childcare facilities were approved to reopen, caring for 18,945 children.Between June 1 and July 31, there were 101 possible child care-associated COVID-19 cases identified at the facility level; among those, 49 were excluded because they had a negative COVID-19 test.Of the remaining 52 confirmed and probable cases, 30 were children; that is roughly .16 percent of the 18,945 children in childcare in Rhode Island this summer. There were 20 teachers and 2 parents who are among the confirmed or probable cases.Cases were confirmed an average of two days after specimen collection.Contact tracing led to the quarantine of 687 children and 166 staff members; that’s roughly 3.6 percent of the total children in Rhode Island care facilities this summer being impacted by quarantine efforts.The cases happened at 29 of the 666 childcare facilities, in 20 of the facilities, there was a single coronavirus case and no transmission. Five of the 29 programs, 15 percent, had two to five cases.The remaining four coronavirus cases may or may not have had secondary transmission. Health officials state those facilities were breaking protocol by moving members of a cohort around to other classrooms, delayed reporting of symptoms, etc. that made it difficult to track.The CDC warns these results were only possible because of decreasing COVID-19 rates in the state, and the community effort to slow the spread of coronavirus. This includes wearing masks and practicing social distancing when around other people.“I understand masks can be uncomfortable to wear and hard to remember to bring when you go out,” Dr. Redfield said. “Schools are not islands in and of themselves, they are connected to the communities around them.”The study says maintaining stable staffing was one of the most difficult things; needing to cover teacher breaks, vacations, etc. while still maintaining the smaller cohort sizes.They recommend additional funding to continue with the smaller class sizes. 3271
A man was accidentally killed by a chainsaw Monday while helping a neighbor cut tree branches during Hurricane Irma cleanup.Authorities say a branch became entangled with the chainsaw. It kicked up and cut Wilfredo Hernandez's throat.Hillsborough County Fire Rescue responded and used a harness to lower him from the tree, but he was pronounced dead at the scene.The map below shows where the incident happened. 419
A school district in Louisiana has acknowledged that some of its customs and practices, including sponsoring morning prayer over the public address system, have violated the First Amendment.The admission comes as part of a consent decree agreed upon by the district, Christy Cole and her daughter, Kaylee. The Coles sued in January?after saying they'd had enough of what they called forced prayer in school. In their lawsuit, they alleged the Webster Parish School District engaged in a systematic, official promotion of religion.The consent decree does not have any impact beyond Webster Parish, but ACLU lawyer Bruce Hamilton said it sets a precedent for how schools act with regards to prayer and religious proselytizing."This really is the wake-up calling and a warning shot to other school districts ... that they can't get away with it without violating the Constitution," said Hamilton, who worked with the Cole family on the lawsuit.The lawsuit sparked deep reflection and frustration in Webster Parish. Faith is deeply personal, but it's also interwoven with everything in the town.It's common to see a large cross in the front yard of a house. Seven churches dominate the two main roads in the town of Minden. A sign advertises a pest control business with a nod to a Bible verse: John 3:16. Sheriff's cruisers and ambulances proclaim, "In God We Trust."When you ask residents if they can separate God from their daily lives, you get a resounding "No."Which is why Christy Cole felt it was important to ensure her daughter, an agnostic, was not being forced into public prayer."For our family, religion is a deeply private matter, and school officials have no business interfering with my daughter's personal religious beliefs," Christy Cole said in response to the consent decree. "I don't want any student to have to go through what my daughter did, and I'm hopeful that because of this agreement, no student will."Prayer over the loudspeaker each morning was just the beginning of an unconstitutional indoctrination of students promoted and supported by teachers, the principal, the superintendent and the school board, the Coles claimed in their lawsuit."Virtually all school events -- such as sports games, pep rallies, assemblies, and graduation ceremonies -- include school-sponsored Christian prayer, religious messages and/or proselytizing," read the lawsuit.The school district acknowledged some of these actions in the consent decree, concurring they had violated the First Amendment's Establishment Clause, which forbids governments from making laws "respecting an establishment of religion."Among those policies and practices: 2662