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WASHINGTON, Sept. 14 (Xinhua) -- Controlling diabetes may someday involve mining stem cells from the lining of the uterus, Yale School of Medicine researchers report in a new study published Wednesday in the journal Molecular Therapy. The team treated diabetes in mice by converting cells from the uterine lining into insulin-producing cells.The endometrium or uterine lining, is a source of adult stem cells. These cells generate uterine tissue each month as part of the menstrual cycle. Like other stem cells, however, they can divide to form other kinds of cells.Led by Yale Professor Hugh Taylor, the researchers bathed endometrial stem cells in cultures containing special nutrients and growth factors. Responding to these substances, the endometrial stem cells adopted the characteristics of beta cells in the pancreas that produce insulin. Over the course of a three- week incubation process, the endometrial stem cells took on the shape of beta cells and began to make proteins typically made by beta cells. Some of these cells also produced insulin.After a meal, the body breaks food down into components like the sugar glucose, which then circulates in the blood. In response, beta cells release insulin, which allows the body's cells to take in the circulating glucose. In this study, Taylor and his team exposed the mature stem cells to glucose and found that, like typical beta cells, the cultured cells responded by producing insulin. The team then injected diabetic mice with the mature, insulin-making stem cells. The mice had few working beta cells and very high levels of blood glucose.Mice that did not receive the stem cell therapy continued having high blood sugar levels, developed cataracts and were lethargic. In contrast, mice that received the cell therapy were active and did not develop cataracts, but the animals' blood sugar levels remained higher than normal.The Yale team's findings suggest that endometrial stem cells could be used to develop insulin-producing islet cells, which are found in the pancreas. These islet cells could then be used to advance the study of islet cell transplantation to treat people with diabetes.Taylor said in a statement that the next step in the research will be to verify how long this treatment remains effective.
MOSCOW, Aug. 24 (Xinhua) -- A Russian Progress cargo ship crashed into Siberia after failing to reach the right orbit Wednesday. The crash marked the second failure in space launch in less than a week and the third in this year, prompting local media to suspect a major reshuffle in Russia's space industry.UNPRECEDENTED FAILUREThe Progress M-12M unmanned freighter was launched to the International Space Station from Baikonur space center in Kazakhstan on Wednesday. It was expected to reach a near-Earth orbit in about nine minutes after launch.However, after the 325th second of the flight, which was just a few seconds before the vessel should reach the orbit, the ground control center lost it.Russian space agency Roscosmos confirmed later that the cargo ship failed to reach the orbit and fell down. Russian Progress M-12M cargo ship is launched to the International Space Station from Baikonur space center in Kazakhstan on Wednesday, Aug. 24, 2011. It has failed to reach the orbit, the Interfax news agency reported.The malfunction of the Soyuz-U rocket's engine was generally believed to be the cause of the accident, according to local media.A source in the space industry said the spaceship had sent a breakdown report while separating from the Soyuz rocket.Some unconfirmed reports said the fuel tank of the booster leaked and the engine was automatically turned off to avoid explosion.The wreckage of the Progress cargo ship has already fallen in southern Siberia's Altai Republic, where a big explosion was heard by locals, reported RIA Novosti news agency.A state investigation committee has been formed to look into the first ever loss of a Progress freighter.CONCERNS OVER FUTUREThe unprecedented accident raised concerns over the reserves of the six crew members on board the ISS.The ship was loaded with over 3.5 tons of supplies for the ISS, including scientific materials, oxygen, water and food.According to Russia's Ground Control, the loss of these supplies will not affect the ISS crew as there are enough stocks of necessities for two to three months.Also, there is no need for premature return of the crew, said Vladimir Solovyov, a space official.However, it still casts some shadow over the ISS program that relies on Russia exclusively following the retirement of U.S. shuttles.A source from the Russian space industry said the scheduled launches of the Soyuz rockets are likely to be suspended until the reasons of the accident are established.This means that current crew members of the ISS would likely stay longer in the space than planned, as the new members might not be able to replace them on schedule, the source explained. Solovyov said the launch of the next Progress is scheduled for October 28.So far, Roscosmos has refrained from comments regarding the possible halt in manned missions aboard Soyuz carrier rockets."Comments will follow. Now it is necessary to determine the causes of today's abortive launch of a Soyuz-u carrier rocket with the Progress M-2M transport ship," Roscosmos told Itar-Tass news agency.Local media raised the prospect of a major reshuffle in Russia' s space industry as the country has lost a total of six space vehicles over the past nine months.On Aug. 18, a carrier rocket Proton-M failed to deliver to the orbit communication satellite Express-AM4. Earlier in February, Russia had lost a satellite named Geo-IK2.In December 2010, a booster malfunction resulted in the loss of three satellites in the global positioning and navigation system GLONASS.
ISLAMABAD, Sept.4 (Xinhua) -- Pakistan's eastern Punjab province is in the grip of a dengue epidemic with dozens of cases being reported daily at various hospitals across the province, said officials and hospital sources.A report issued by the provincial health department on Friday said that as many as 145 cases of dengue fever in Lahore, the provincial capital, and several other cities have been reported in Punjab over the past three days.The total dengue fever cases in the Punjab are 1,419 since the beginning of this year, out of which 1,358 Dengue patients had recovered and been discharged from hospitals, according to local media.Dengue, an acute febrile disease spread by the bite of the aedes aegypti has been endemic in Pakistan for the last few years. It spreads most often after the rainy season in July and August when pools of standing water serve as ideal mosquito breeding spots.Gravity of the dengue disease was felt at the central level and Prime Minister Yusuf Raza Gilani extended full support to the Punjab government in coping with the growing number of cases of dengue fever.The Prime Minister, who was in Lahore on Friday, directed his Principal Secretary to contact the Punjab government and assist them in taking necessary preventive measures against the Dengue fever. He also asked him to extend offer on behalf of the federal government for provision of any technical expertise to the Punjab government.Acting on reports that the virus was spreading rapidly and that measures to control it had been unsuccessful, Punjab Chief Minister Shahbaz Sharif has presided over series of meetings and ordered the immediate suspension of the Lahore district health officer for failing to control the epidemic.A task force comprising a government minister, health officials and doctors has been set up to review the situation and suggest measures to curb the virus.On the orders of the chief minister, giant advertisements on measures that can be taken to prevent dengue have appeared in the media.People have been advised not to allow water to stand in containers, to use mosquito repellents, spray homes and be particularly vigilant at dawn and twilight when the dengue- carrying mosquitoes bite.This increase in public vigilance and awareness may yet halt the spread of a disease that over the past few weeks has struck across the province, said specialists.Meanwhile, the Health Department spokesman also stressed awareness among the people for prevention, control and treatment of dengue virus. According to him, the symptoms of dengue fever include high fever, severe body pain, itching and red spots, bleeding from nose and teeth and severe pain in the eyes. He said precautions include proper covering of the pots having water, like buckets and drums, and using coils, mats and sprays for eliminating mosquitoes.He further said dengue mosquitoes usually attack early in the morning from 6 a.m. to 9 a.m. and from 4 p.m. to 10 p.m.in the evening. The patients should act upon the advice of qualified physicians only, he maintained.
BEIJING, July 6 (Xinhua) -- The Ministry of Health has issued a national standard on compound food additives to better regulate the production and use of such additives and ensure food safety.Compound food additives, which are designed to improve food quality or assist in food processing, should be used sparingly in food products, according to the standard the ministry issued Tuesday.Titled the General Rule on Compound Food Additives, the standard stipulates that each of the ingredients used for making compound food additives, which are a mix of two or more single food additives, should meet national standards concerning food safety.No chemical reaction should occur and no new compounds should be generated during the production process of compound food additives, according to the standard.Compound food additives producers should clarify limits of the amounts of harmful substances, such as lead and arsenic, in their products and take measures to control the levels of harmful substances, according to the standard, which will come into effect on Sept. 5 this year.
BERLIN, June 1 (Xinhua) -- Germany's disease control center reported on Wednesday 365 new cases of the fatal enterohemorrhagic E. coli (EHEC), which marked a sharp rise since its outbreak in the middle of May.Twenty-five percent of the new cases involved the hemolytic- uremic syndrome (HUS), a serious complication resulting from E. coli infection that affects the blood and kidneys, Germany's Robert Koch Institute said.Until now 17 people in Europe, one in Sweden, the other in Germany have been killed by the deadly disease, while the source of the infection was still not identified.According to the data of Robert Koch Institute, at present 470 patients are suffering from HUS due to the infection, raising concerns that the death toll could be even higher in the future.Germany's Agriculture and Consumer Protection Minister Ilse Aigner defended Germany's previous alert on cucumbers from Spain on Wednesday."The fatal strain of EHEC bacteria was indeed found on Spanish cucumbers. According to the European rules, a quick warning must be sent out," she told a local TV station.Laboratory tests in Hamburg on Tuesday overthrew the previous finding that Spanish cucumbers were the sources of the outbreak.As a result of the alert, Europe and Russia imposed bans on Spanish vegetables, leaving Spanish farmers a loss of 200 million euros (287.5 million U.S. dollars) a week.Spain has expressed its intention to take possible legal actions against authorities in Hamburg and ask for compensations from Germany and the European Union.