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A surge in COVID-19 cases is further straining the already-depleted supply of prescription drugs in the U.S., according to researchers and doctors at the University of Minnesota."The supply lines are really stressed and stretched," said Dr. Stephen Schondelmeyer, a co-principal investigator for the Resilient Drug Supply Project at the University of Minnesota.Schondelmeyer's work focuses on critical drugs and their supply chains. He tracks the supply chain process for every drug on the marketplace — more than 100,000 in total.Most of the prescription drugs used by Americans are made outside of the country — meaning the U.S. is reliant on foreign companies to manufacture the drug and shipping companies to deliver them safely."We're identifying where it comes from — the first thing you need to know is about 70% of all the drugs that come into the U.S. marketplace are made outside of the US.," Schondelmeyer said.He and his team want to predict and identify when and where there will be failures in the system. Right now, the U.S. has a "fail and fix" system — and right now, there are some critical breakdowns in the supply chain."Seventy-five percent of the COVID-19 drugs are currently in shortage," Schondelmeyer said. "That means three-fourths of the drugs we're using for COVID-19 were already in shortage, and that's before we had this last surge we're seeing.""We should, as a matter of national policy, have a map like we're building of the global drug supply from the beginning all the way until the drug reaches the patient," Schondelmeyer said.But it's not just COVID-19 drugs that are in short supply. Dr. Beth Thielen, an assistant professor of pediatrics at the University of Minnesota Medical School and an infectious disease physician, says even some routine drugs are hard to come by."As a physician working in the hospital — the University of Minnesota — we're a big urban center and yet we're regularly dealing with this issue of shortages in routine things like antibiotics," Thielen said. "It's very concerning to think about the supply chain breaking down and seeing drugs not available in pharmacies or the hospital."Doctors say COVID-19 has unmasked a problem that's been a concern for decades. The pharmaceutical supply chain is complicated and dependent on other countries — and there are supply and demand dilemmas."Start the conversation now with your healthcare provider," Thielen said. "There might be some within class substitutions of medicines, so a drug that is related may not be the exact same drug but might fulfill the same purpose."Schondelmeyer adds that anyone with a regular prescription should ask their doctor about getting a 90-day supply of essential drugs — but adds that there's no reason to hoard medication."We shouldn't panic. We shouldn't treat drugs like we did toilet paper and stock up on so much that we're totally out — and that's an example of what can happen when there's rumors of shortages," Schondelmeyer said. "People act out of fear, and they hoard more than they really need."In the meantime, Schondelmeyer is pushing for a national stockpile of critical medications, so that the U.S. is covered should there be a complete breakdown in the supply chain. 3236

A suspect has been arrested and the gun and mask have been recovered after an incident at the Boulevard Mall in Las Vegas, according to police. The gun appears to be a fake gun, according to police. The identity of the suspect will be released Friday morning.  Police said they received calls about a person with a gun at the Boulevard Mall on Maryland Parkway. No injuries were reported and police say no shots were fired. The mall was evacuated while officers made sure the person with a gun is not inside the mall. Deputy Chief Chris Jones told the media during a press briefing that video has been obtained of a person wearing a mask and carrying a long gun. The incident began shortly after 7 p.m. Watch video from inside the Boulevard Mall belowAs the news first broke earlier tonight, thoughts of the Las Vegas shooting came to mind. But when it comes to mall shootings in Las Vegas there have been a few isolated incidents. In July 2014, one person was injured during a shooting at the Fashion Show Mall. In that case, police reported a scuffle broke out and one man was shot in the neck. There was another shooting in May 2016 in the parking lot at Fashion Show Mall.This occurs at a crucial moments for Boulevard Mall. The more than 50-year-old shopping center was once the premier mall in the city but fell into disrepair. It was sold in 2013 to developer Roland Sansone for .5 million and then embarked on a million renovation project.It’s had some near-term ups and downs. After the SeaQuest Aquarium announced in 2016 it would open, Macy’s and J.C. Penney both said last year they would close. In 2018, Sansone announced the Galaxy Theater would open in the fall and Anthem Blue Cross Blue Shield will open in the second story of the former Macy’s space.Facebook live video from Mahsa Saeidi at the scene  1894

A month ago, a former student roamed the halls of Marjory Stoneman Douglas High, opening fire on terrified students and teachers at the Florida school.The massacre of 17 students and faculty members added to a grim statistic: three of the 10 deadliest mass shootings in modern US history happened within five months of one another. In the four weeks since the Valentine's Day shooting, the survivors have turned into activists on the national stage. Even as they grieve, they've demanded action on gun reform. In between congressional meetings and protests, they've attended memorials and funerals. 606

A new toilet is headed to the International Space Station this week, in addition to new foods to grow and beauty products.The million toilet system is known as the Universal Waste Management System. It’s 65 percent smaller and 40 percent lighter than the toilet currently used on the space station.“I know it’s a toilet and I get a big laugh from my friends all the time, ‘Oh, he’s building a toilet.’ But it’s not just a toilet, it’s a titanium space toilet,” said Jim Fuller, Program Manager for the UWMS project at Collins Aerospace.That hefty price tag includes fans to create “gentle air flow to help collect waste in microgravity,” and will help NASA reach their “goal of 98 percent water recovery for deep space missions.” The new system can also handle larger crews, requires less maintenance, and better accommodates female astronauts. 856

A study conducted by Stanford researchers found nearly 10% of those tested exhibited coronavirus antibodies. The study was published in the Lancet earlier this week.The study involved dialysis patients and randomly tested over 28,000 samples. The samples were taken in July as part of the patients’ treatment.The data found stark differences based on region. The northeast around 27% of patients with coronavirus antibodies, compared to 3.5% in the west.The study’s authors stressed that the study oversampled minorities. Minorities, the study found, were considerably more likely to have coronavirus antibodies than the rest of the population.“Uncertainty exists as to whether seroprevalence estimates in the dialysis population can be extrapolated to the US population more broadly,” the study reads.The study indicated that herd immunity is still far off, as estimates say at a minimum, 50% of the US population would need to be infected to reach that level. 969

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