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SAN DIEGO (KGTV) -- Caltrans is warning drivers about a series of SR-163 closures throughout the week. According to the agency, all lanes of north and southbound SR-163 between I-8 and Genesee Avenue for three to six nights. The highway will be closed so crews can remove falsework from the bridge on the SR-163 Friars Road overcrossing. The southbound closures will begin at 11 p.m. with the northbound closures starting at 11:30 p.m. All lanes will reopen at 5 a.m. The list below shows which lanes will be closed on certain nights: Sunday: All southbound lanes, the northbound far right collector lane and the right main lane (slow lane).Monday: No full freeway closure. Only the northbound and southbound right main lanes.Tuesday: All southbound lanes, and the northbound left lane (fast lane).Wednesday: All northbound lanes, and the southbound left lane.Thursday: No full freeway closures. Only the northbound right lane.Friday/Saturday: No freeway work scheduledSunday, March 10: All northbound lanes. During the closures, drivers on the northbound SR-163 will be rerouted to eastbound I-8 to northbound I-805 to the merge at northbound SR-163.Southbound motorists will be rerouted to southbound I-805 to westbound I-8 to the southbound SR-163 connector ramp. 1274

SAN DIEGO (KGTV) -- Chula Vista City Councilman Steve Padilla remains hospitalized on a ventilator but is now in stable condition, according to a family statement issued Wednesday. Padilla, who represents Chula Vista's District 3, was admitted at UCSD Thornton Hospital ICU last Thursday after experiencing difficulty breathing associated with COVID-19. The family said he required a respirator.“My dad is a fighter, and he’s fighting through this -- with the help of amazing doctors, nurses and healthcare workers who are caring for him," said the councilman's daughter Ashleigh Padilla in a statement Wednesday night."We’re hopeful that he’s reached a turning point and will be home soon," she said.No further details about his condition were given at this time.“I know he cannot wait to get back to serving the people and helping our entire community get through these tough times," his daughter said.Padilla told his constituents in a Facebook video post published March 14 that he had contracted the coronavirus. He appeared to be in good spirits as he told viewers that he was doing "very well" and "feeling well.""After recently experiencing symptoms, I was diagnosed as being positive for the COVID-19 virus, also known as the coronavirus," he said last Saturday.In a follow up statement that night, Padilla described having a fever, body aches, headaches, chills, that "came on very rapidly." He noted he had come into contact with friends, colleagues, and the public over the last week."I’m in close coordination with County Public Health officials who are taking all precautions to ensure the health of people I’ve been in contact with," he said.Padilla issued a warning to the public through his daughter last Thursday: “Everyone needs to take COVID-19 seriously. Please follow the advice of our public health professionals to reduce spread of the virus and take precautions to keep your families and our community safe," said Ashleigh Padilla.Padilla previously served as Mayor of Chula Vista from 2002-2006, and is a former officer and detective with the Chula Vista Police Department.On the Chula Vista city website, Padilla is noted for being the first person of color ever elected to City office in Chula Vista history, the first Latino Mayor, and the first openly LGBT person to serve or be elected to city office. 2342

SAN DIEGO (KGTV) -- Capt. Andy Williams, Commander of the California Highway Patrol Oceanside Station, is under investigation after his arrest for suspicion of domestic violence.ABC 10News obtained the request for a restraining order against Williams, filed by his ex-wife. In the court documents, she details an argument the two got into at his home in Carlsbad Oct. 19. She claims he struck her near her buttocks with enough force to leave a hand mark and welts.Carlsbad police confirmed to ABC 10News that they arrested Williams. A spokesperson for the District Attorney tells ABC 10News they are investigating the case to decide whether to file charges.Williams is out on bail. CHP has placed him on administrative leave and removed his powers as a peace officer.CHP Border Commander Chief Omar Watson sent ABC 10News a statement:"The CHP is aware of the arrest of Capt. Andy Williams by the Carlsbad Police Department for alleged behavior that occurred while the employee was off duty. The CHP continues to fully cooperate with the investigating agency and we are conducting our own investigation into the allegations. I want to assure the public that we take any allegation of misconduct by our employees, whether on or off duty, very seriously.I also want to emphasize to the public that the alleged conduct of this employee does not reflect the values, hard work, dedication and professionalism of the CHP and its more than 11,000 employees, who proudly work each day to provide the best in Safety, Service, and Security to the people of California." 1566

SAN DIEGO (KGTV) - Bringing the entire family out for a day at the fair can get expensive. That's why the San Diego County Fair has set up some sweet deals for families.The biggest deal offered is the fair's season pass, which gives guests admission on all 26 days for . Which means the savings start of day two for adults and day three for children and seniors.One discount many locals expect every year is right at the checkout line. Albertsons and Vons grocery stores will sell discounted tickets at for adults and for seniors and children. Customers must have a minimum purchase of .RELATED: What to know about 2018's San Diego County FairThe grocery stores are also selling tickets for fair days, which are held on June 1, June 2, and June 6. The Passport to Savings book also includes a free return ticket to the fair. The coupon books sell for ahead of time and regularly, and include an array of coupons to use inside and outside the fair.And of course, the fair's Pay One Price Ride Days returns, offering unlimited rides for a flat rate on June 6-7, 13-14, 20-21, and 27-28.There are a number of other ways to save on tickets: 1187

SAN DIEGO (KGTV) — As the world waits for a vaccine against the coronavirus, two San Diego biotechs are teaming up to develop a nasal spray using designer antibodies cloned from COVID-19 survivors.About 70 companies worldwide are working on therapies for COVID-19 using cloned antibodies, according to an estimate by the International AIDS Vaccine Initiative. A few of these treatments, known officially as monoclonal antibody therapies, have advanced to clinical trials.Most require an injection, but San Diego-based Diomics and its partner Active Motif, based in Carlsbad, are developing a once-a-day spray that could be easily self-administered.Early research suggests the coronavirus primarily enters the body through the nose. The spray, called Dioguard, is designed to coat the lining of the nasal cavity with cloned antibodies that are held in place for 24 hours or more using a proprietary polymer material developed by Diomics.Diomics CEO Anthony Zolezzi said he believes the spray “holds the key to allowing many aspects of life to resume until the day comes when there’s an effective vaccine in widespread use.”Diomics is also developing two tests for COVID-19 antibodies using its polymer beads, including a device that looks like a nicotine patch that is designed to monitor for infections for a week or more.RELATED: How a dot on your forearm could be the future sign of COVID immunityActive Motif is providing the cloned antibodies for the nasal spray. With a lab in Shanghai and other relationships in China, the Carlsbad company was able to clone antibodies from 11 Chinese survivors in February, before the World Health Organization declared a pandemic.When the company started the cloning project, they thought the virus would probably disappear in three to six months, said Active Motif CEO Ted DeFrank. “Then people started realizing, no this is going to be with us for a while.”The plasma from the 11 Chinese patients contained thousands of antibodies, and scientists with Active Motif set about selecting the one that was most effective, dubbed 414-1. The company says it can neutralize SARS-CoV-2 virus particles with 98 percent effectiveness.Monoclonal antibodies have some similarities to convalescent plasma, which is a complex cocktail of antibodies and other immune molecules drawn from the blood of recovered patients. One of the key differences is that cloned antibodies can be mass produced in a lab.Cloned antibodies have been used in treatments for more than 30 years, primarily for cancer. One such treatment famously helped former U.S. President Jimmy Carter beat melanoma.But of the more than 100 monoclonal antibody therapies licensed for use, only seven are for communicable diseases, according to IAVI.Historically, the treatments have been expensive and difficult to produce, but Diomics said it’s targeting a price of about a spray for Dioguard, roughly per bottle.“We do not want to have huge profits from a pandemic, that’s just wrong,” Zolezzi said. “We’re going to price this as effectively as we can for the masses. We want to get this out to the masses.”Animal testing is about to begin and the companies said they hope to progress to human trials soon. Their goal is to release the spray in early 2021, when a vaccine may be on the market but not yet widely available.If the spray works, it could be adapted to other viruses to help fight future pandemics, Zolezzi said."That’s our real goal," Zolezzi said. "That we never get caught flat-footed like this time." 3526

来源：资阳报