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WASHINGTON, April 25 (Xinhua) -- A class of drugs that shows promise in breast and ovarian cancers with BRCA gene mutations could potentially benefit colorectal cancer patients with a different genetic mutation, a new study from the University of Michigan Comprehensive Cancer Center finds.Working in cell lines from colorectal cancer patients, researchers found that the class of drugs called PARP inhibitors worked against tumors with mutations in the MRE11 gene.About 15 percent of all colorectal cancers have what's called microsatellite instability, a type of error in the DNA. About 82 percent of those tumors have the MRE11 gene mutation."This is a potential broader application for PARP inhibitors, beyond breast and ovarian cancer. This is a class of drug that's already shown safety in early clinical trials and now might benefit some colorectal cancer patients as well," says lead study author Eduardo Vilar-Sanchez, a hematology/oncology fellow at the university, in a statement.The study, which was published Monday in Cancer Research, also found that PARP inhibitors are even more effective when both copies of MRE11 were mutated. Each person carries two copies of each gene, which means mutations can occur in either one or both copies. The researchers suggest that PARP inhibitors could be targeted specifically to colorectal cancer patients who have two copies of the mutated gene.Researchers are planning a phase I clinical trial to look at using PARP inhibitors in colorectal cancer patients with two mutated copies of MRE11. Future trials are being considered using PARP inhibitors to prevent colorectal cancer and other cancers in people with Lynch syndrome whose tumors have this mutation.Microsatellite instability is also seen in prostate cancer and endometrial cancer, suggesting potential for PARP inhibitors to play a role in additional types of cancer as well, Vilar-Sanchez says, adding that more research is needed in these areas.

WUXI, Jiangsu, Feb. 17 (Xinhua) -- Chinese Vice Premier Zhang Dejiang said Thursday that developing quality labor and vocational skills would greatly contribute to the social and economic development of the Asia-Pacific region.He made the remarks while delivering a speech at the opening ceremony for the APEC (Asia Pacific Economic Cooperation) Skills Development Promotion Center which was launched in China's eastern city of Wuxi.The Center will play a positive role in enhancing human resources cooperation between APEC members and achieve "inclusive growth" in the region, Zhang said.The Chinese government has always held that human resources are the most important resource in social and economic development, and it would continue to actively take part in APEC activities that encourage regional exchanges and cooperation in human resource development, he said.China would fully support the APEC Skills Development Promotion Project and the development of the center with financial and technical backup, making it a platform for vocational training and personnel exchanges between APEC members, he added.The decision to establish the center was announced by Chinese President Hu Jintao during the 18th APEC Economic Leaders' Meeting in November last year, which sought to advance cooperation on human resources within the APEC framework.

CAIRO, Jan. 23 (Xinhua) -- As part of bilateral efforts to enhance cultural cooperation between the two great civilizations, China, as the Guest of Honor, will participate in the 43rd Cairo International Book Fair in Egypt."An outstanding Chinese delegation will attend the fair to inform the Egyptian people all about Chinese culture," said Chen Dongyun, cultural counsellor of the Chinese Embassy in Egypt.Some 248 publishers, 13 renowned scholars, writers and artists will display about 10,000 books about the achievements made by China in various fields such as politics, economy, science and technology, and culture.The fair, the most important of its kind in the Arab region, will be held on Jan. 29 through Feb. 8 in the Cairo International Conference Center. The annual fair began in 1969.The Chinese hall in the center covers an area of 1,400 square meters, with special areas allocated for a variety of exhibitions about the history of the evolution of Chinese characters, photos reflecting Sino-Egypt friendship and landscape of modern China and intangible cultural heritage.The fair also includes a seminar featuring literature and translation among Chinese and Egyptian writers and artists and a week-long film show in which six Chinese films with Arabic subtitles will be introduced to the audience.Chinese participation reflected the common consensus of the leaders of the two countries to deepen mutual understanding and friendship and will serve to promote the sound and sustainable development of bilateral relations, Chen said.Zhang Jichen, vice president of China National Publications Import and Export (Group) Corporation, which is in charge of the organization of the Chinese activities at the fair, said a cooperation agreement between the General Administration of Press and Publication of China and Egypt's Ministry of Culture.China will also present some 1,000 high-quality books to the National Library and Archives of Egypt and the Alexandria Library.The fair is expected to attract 632 publishers from 29 countries, including 17 in the Middle East. More than two million visitors participate in the fair each year.

BEIJING, March 24 (Xinhuanet) -- Mozilla's newly launched Firefox 4 Web browser was downloaded nearly 7 million times worldwide in the first 24 hours, according to media reports.The number was almost triple the 2.4 million downloads that Microsoft reported in the first 24 hours after the Internet Explorer 9 (IE9) was released.Nevertheless, the number lagged behind the record-breaking performance of Firefox 3, which was downloaded more than 8 million times in the first day after launch in mid-2008.Statistics show that Firefox 4 has attracted interest from around the world, with 44 percent downloads in Europe, 26 percent in North America. and 20 percent in Asia.Mozilla launched Firefox 4 on Tuesday at around 10:00 a.m. EDT to compete with Microsoft's IE9 and Google Chrome.The new Web browser was originally scheduled to ship last November, but bugs delayed the release into early this year.Firefox trumped IE9 in the first day download contest because it runs on Windows XP, the 10-year-old operating system that IE9 doesn't support.

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