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LOS ANGELES, July 18 (Xinhua) -- At least 70 genetic mutations may be involved in the formation of colon cancer, far more than scientists previously thought, a new study suggests.The study by researchers at University of Texas (UT) Southwestern Medical Center contradicts previous thinking that only a few mutated genes may play a role in the development of colon cancer."The ways we've been treating patients up to now is to just go after one target when we should be going after three to four different pathways simultaneously," said Dr. Jerry W. Shay, vice chairman and professor of cell biology at UT Southwestern.The new study identified 65 candidate genes and at least five passenger genes whose mutations play significant roles in cancer development. Inactivating the function of any of these tumor- suppressing genes led to a key step in cancer development called anchorage-independent growth, meaning cells piled up on top of each other rather than aligning neatly.According to previous studies, there were 151 candidate genes and that mutations in just eight to 15 of them would lead to cancer. There were 700 other genes classified as passenger genes whose mutations were incidental to cancer growth.Current cancer treatments target just one or two known cancer- driver genes. While patients may get transient tumor burden reduction, almost universally tumor growth returns."Those numbers are dead wrong," Dr. Shay said, suggesting a new approach to colon cancer treatments targeting multiple genes and pathways simultaneously.The next step is further research to classify more accurately which genes drive cancer and which are merely passengers, the researchers said.Study findings were published in the July 2011 Cancer Research (Priority Reports).

TAMPA, the United States, June 18 (Xinhua) -- The HIV/AIDS patients in the U.S. state of Florida are in dispute with state authorities over a proposal to impose tighter restrictions on those who qualify for drugs provided by the state's AIDS Drug Assistance Program (ADAP).According to the proposed restrictions, individuals would have to earn less than 21,000 U.S. dollars annually to qualify for ADAP drugs. If approved by the Florida Department of Health (FDH), this would affect approximately 1,150 HIV/AIDS patients."The FDH is currently looking at the number of cost containment activities, including altering the financial eligibility for ADAP services," said FDH's press secretary Jessica Hammonds. "After soliciting public input on this matter, the department is in the final stages of evaluating the matter."The Florida ADAP program serves almost 9,500 clients, each of whom receiving 8,600 dollars in funding annually, Hammonds said. There are still another 3,482 on a waiting list.Four FDH sponsored public hearings were held in April and May on the proposal to reduce HIV/AIDS funding. Two were held in Miami, one in Tampa, and the other one was held in the state capital city of Tallahassee. Over 1,000 people attended the hearings.The issue has become so ubiquitous that it caught the attention of the Elton John AIDS Foundation (EJAF), created by the popular entertainer of the same name.

BONN, Germany, June 17 (Xinhua) -- The latest United Nations (UN) climate talks ended here on Friday with no surprise -- some " technical issues" saw some progress, as delegates usually said, while major disagreements remained.The two-week UN climate negotiations have made "clear advances" on such issues as extending carbon trading mechanisms, climate fund management and slowing deforestation, Christiana Figueres, UN Framework Convention on Climate Change (UNFCCC) executive secretary, said at a closing press conference.Figueres said delegates from 183 countries stepped forward with a technology mechanism to boost global green technology sharing. The mechanism will include a Climate Technology Center and Network to establish a worldwide clean technology stakeholder community.As for the implementation of a comprehensive package of the Cancun summit last year, this Bonn session has "paved the way" for progress at the next UN ministerial-level climate conference, which is to be held in Durban, South Africa from Nov. 28 to Dec. 9, Figueres said."Strong convergence has emerged on how the Adaptation Committee will be governed, what its composition will be and what its specific role will be," she said. "This progress means that the Committee could be fully operationalized at Durban."The UN climate chief stressed that governments, business circles and civil society cannot solve issues related to climate change "in one meeting," and climate talks are "the most important " negotiations the world has ever seen."The Bonn meeting is practical, focusing on concrete issues. In general, the negotiating process is moving forward step by step and on the right track," Su Wei, China's chief negotiator, told Xinhua on Friday."Despite setbacks and reversals, parties are taking climate change seriously and are willing to promote the negotiations under the Bali Roadmap," he said. "In the past two weeks, contact groups are busy making informal consultations on various topics.""Admittedly, in some key areas, there is a gap among parties," Su said.During the meeting, many delegates and observers have complained that the pace of negotiation was unbearably slow, especially against the backdrop of a new warning from the International Energy Agency, which said the global energy-related carbon emissions rose to a record high in 2010 despite decade-long efforts on curbs.Experts said one of the main hurdles in current talks was still the old topic -- the fate of the Kyoto Protocol, the sole legally- binding pact on industrial countries' emission cuts set to expire at the end of 2012.The protocol, which binds 37 rich countries, has been crippled since Cancun, as Japan, Canada and Russia have clearly stated they would not extend the pact's second commitment period after 2012.The United States, which never ratified the treaty, said it would not accept any legal deal unless other major economies have similar emission constraints.The European Union (EU), the last major bloc that is open to the renewing of the Kyoto Protocol, said its supportive attitude should not be taken for granted. The EU said it would not unilaterally step up efforts on combating climate change if other nations are not willing to do the same.Meanwhile, developing countries insisted that the updating of the Kyoto Protocol remains "the very core issue" of current talks, asking rich nations to shoulder their historical responsibilities and preserve the pact as a major legally-binding instrument to tackle climate change.The Group of 77 and China, representing over 130 developing nations, have said that the renewal of the Protocol should be the priority for Durban.On Friday, Figueres said that "resolving the future of the Kyoto Protocol is an essential task this year and will require high-level political guidance.""By Durban, governments need to come forward with options that will be acceptable to all parties," she said, adding that high- level contacts are necessary to break the ice.She told reporters that environment ministers are due to meet in Berlin from July 3 to 4, known as a continuation of last year's ministerial-level informal talks held in the town of Petersburg near Bonn. Moreover, world leaders are due to discuss climate change on the sidelines of the UN General Assembly in September.Before the Durban summit, delegates have agreed to hold an additional round of climate talks in late September or early October, Figueres revealed.

BEIJING, Sept. 21 (Xinhuanet) -- China will launch an unmanned module next week, paving the way for a planned space station, a spokesman for the space program said on Tuesday.Tiangong-1, or "Heavenly Palace 1", will blast off from Jiuquan Satellite Launch Center in Gansu province between Sept 27 and 30, the spokesman said.The 8.5-ton module, and the Long March II-F rocket that will carry it skyward, were positioned onto the launch pad on Tuesday, signaling that the project has entered the final preparation stage."Scientists will conduct final tests in the next few days before injecting propellants for the launch," Cui Jijun, director of the Jiuquan Satellite Launch Center, said.The program spokesman said that Tiangong-1 will serve as "a target spacecraft" for rendezvous and docking experiments.It will also work as "a platform to test long-term unmanned and short-term manned operations", he said.Technical and medical experiments will provide crucial data ahead of the building of the space station (scheduled for 2020).Three rendezvous and docking experiments will be conducted.An unmanned Shenzhou-VIII craft will be launched later this year to dock with Tiangong-1. In 2012, Shenzhou IX and Shenzhou X will blast off to complete at least one manned docking.Jiao Weixin, a space scientist at Peking University, said that rendezvous and docking - vital maneuvers for manned programs - are hard to master."Rendezvous and docking are difficult because it is like asking two racing cars to keep a distance of 1 meter between them," he said.The mission requires two craft, traveling at speeds of 28,000 km/h, to enter the same orbit and connect with precision, he said.The China Manned Space Engineering Office rescheduled the launch of Tiangong-1 after the failed launch of an experimental orbiter last month.The spokesman said that the carrier rocket to blast off with Tiangong-1 atop has been modified.Only the United States and Russia have mastered rendezvous and docking technology, said Pang Zhihao, deputy editor-in-chief of the magazine Space International.Spacecraft developed by Europe and Japan have utilized US and Russian technology to dock with the International Space Station, he added.