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As states across the country grapple with an increase in coronavirus cases and a huge demand for tests, many businesses are looking for other ways to get more mileage out of their supply chain.Like with anything else, supply and demand is a constant struggle. In this unprecedented era, the demand for things like coronavirus tests is so large that public health departments don't have a choice but to figure out ways to make our supplies last. Several states are examining pooled testing. California's Public Health Department says it's to "better leverage testing resources."Pooling is something that blood banks have used for decades to keep their blood supply safe. Dr. Claudia Cohn is the Chief Medical Officer of the AABB, formerly known as the American Association of Blood Banks.“If you have 100 people that need to be tested and if you test each of them, you’ll do 100 tests. If you find that your test is sensitive enough that you can pool together 20 samples at the same time, instead of having 100 tests, you can have five pools of 20,” Dr. Cohn said.Now, if one of those five pools is positive, then Dr. Cohn says, "You’ll need to break it out and test each of those separately. So, let’s say you have one positive person in a pool of 100 people, you either do 100 tests and find one positive or you do five pools of 20, four of those pools will be negative, so you’ve done 4 pools and covered 80 people."The test works by taking a tiny sample from each person who was tested.“When you take a swab from everyone’s nose, you isolate the DNA from that swab,” Dr. Cohn said about the PCR test, which is generally a nose swab. “It’s not a lot, it’s a small amount but it’s enough. Because these tests are very, very sensitive.”Those tests are so sensitive, and they have to be, that pooling can really only work if the test can handle, as in detect, multiple samples at once. The FDA mandates that.“The FDA is quite demanding as they should be in terms of making sure tests work well and are safe,” Dr. Cohn said.And Dr. Cohn says, pooling wouldn't work in an area where there's a large outbreak, which means a large number of people would test positive regardless of pooling. In the blood world, this strategy has been perfected.“You are taking 100 samples and taking a drop from each sample and putting it together,” Dr. Cohn said. “You are testing every single person who comes through. In the blood world safety is before everything."Blood banks test for HIV, Hepatitis C and B and well as COVID-19 antibodies, according to the American Red Cross. And, as this pandemic moves through our communities, Dr. Cohn says our blood supply needs to remain strong.“After that initial spike, it went down again and that was okay because elective surgery had been canceled, so the demand for blood had gone down as well so for a while we were at a good balance of demand and supply. But then elective surgeries opened up and hospitals went back to full service and we’re in a shortage again,” Dr. Cohn said. 3017

As the FBI and US law enforcement agencies turn to the catching the serial mailbomber, or mailbombers, terrorizing those who have been labeled by President Donald Trump as political enemies, it's interesting to follow in their steps and examine what we know about the now 12 packages that have been intercepted.All those we have seen were all in manila envelopes, for instance, with the same return address. They all had six forever stamps, which was enough to get some to mail sorting facilities, but another needed more postage. They all had the same return address, with a misspelled name for Debbie Wasserman "Shultz," not Schultz, a Democratic congresswoman from Florida who is the former chairwoman of the Democratic National Committee.There are images of five of the packages, one of which -- one of the packages sent to Democratic Rep. Maxine Waters of California -- was shared by both DC Police and the FBI on social media.Related: The manhunt - FBI treating serial bomber as domestic terrorism  1017

ATLANTA (AP) — The shooting death of an 8-year-old girl has prompted a ,000 reward for information as authorities in Atlanta search for at least two people who opened fire on the car she was riding in. Police identified the girl as Secoriea Turner, and say she was in a car whose driver tried to get through an illegal barricade placed near Wendy's restaurant where Rayshard Brooks was killed by a white police officer on June 12. In a news conference on Sunday, Atlanta Mayor Keisha Lance Bottoms said "enough is enough" and asked for the public's help in identifying the shooter. 592

At least three people died and 67 were injured after a tanker truck exploded on a highway in Bologna, Italy, a spokesman for Italian state police told CNN.Marco Granna, a spokesman for the local health agency in Bologna, told CNN that 55 people were taken to the hospital for treatment of first-, second- and third-degree burns.At least two of the injured are police officers, the Italian highway patrol told CNN.Footage of the incident showed an enormous fireball and plumes of thick, black smoke in the sky .The explosion ripped through the pavement, leaving huge holes in the road surface.According to police, the incident took place at Bologna Casalecchio and the junction with the A14 route from Bologna to Taranto.  734

ATLANTA — Georgia's legislature on Tuesday passed hate crimes legislation deemed essential by state leaders, sending the measure to Gov. Brian Kemp's desk.Georgia is currently one of four states in the U.S. without hate crime laws.The price Republicans exacted for moving that legislation forward was the simultaneous passage of a bill that would mandate penalties for crimes targeting police and other first responders.The action comes after Senate Republicans had added police as a protected class to the hate crimes legislation last week, but then moved those protections to a separate bill in a deal between the parties.Kemp's office said in a statement that he'd sign the hate crimes bill, pending a legal review.The bill's passage comes amid weeks-long protests against systemic racism throughout the country. The protests were sparked by the death of George Floyd, who died in police custody in Minneapolis after bystander video showed an officer kneeling on his neck for more than eight minutes.The passage also comes weeks after three arrests were made in connection with the shooting death of Ahmaud Arbery. The 25-year-old Arbery was killed in Burnswick, Georgia in February, and his case changed jurisdictions several times due to one of the suspect's connections with the local District Attorney's office. It wasn't until days after a video of the altercation leaked to the public in May that two of the men, Gregory and Travis McMichael, were arrested and charged with murder. A third man, William "Roddy" Bryan, was also charged with murder a few weeks later. 1582

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