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Detroit has one of the highest violent crime rates in America, according to the FBI.The challenges here have opened the door for a growing industry: private security. “The landscape is growing, because there is a greater need for protection than ever before,” says Dale Brown. “Our mission is to protect that person’s business from a violent encounter."Brown is the founder of the 394

Depression. Exhaustion. Burnout. Stress. Those are just some of the words people are using to describe their experiences as caregivers. Helping care for a family member or loved one can be hard work. People don't often talk about the emotional toll it can take on the actual caregiver. Now the 307

Jumping back into the dating scene after 15 years of marriage was daunting for Lori. "I've done it all. I've done eharmony, Match.com and all the apps," she says. But nothing worked. "I was trying too hard to be someone I wasn't,” Lori says. She decided to enlist the help of relationship expert Hilary Silver. "They just don't know what they are doing; they don't know how to date, present themselves,” Silver says of older adults getting back into the dating game. “They don't know the new rules or dating in the modern world." Silver says Lori’s problem was how she was presenting herself, because it was a turn off.Silver describes the top three personality turn-offs.There's the pleaser. Silver says that’s the category Lori falls in. She says pleasers do anything and everything to be liked. There are the pushers. They're more guarded and have a chip on their shoulder, which causes them to push people away. Then, there are the perfectionists, who feel they need to be perfect to be loved. Lori had to learn how to be herself, to reconnect with the things that make her happy, Silver says.Her hard work payed off. Lori went on a blind date and found a connection. 1192

INDIANAPOLIS — The U.S. Food and Drug Administration on Monday granted emergency use authorization to Eli Lilly and Company's experimental COVID-19 antibody treatment bamlanivimab.According to a statement from the company, the drug is authorized for the treatment of mild to moderate COVID-19 in adults and pediatric patients 12 years and older with a positive COVID-19 test who are at high risk for progressing to severe COVID-19 and/or hospitalization. Lilly said in a statement the drug should be administered as soon as possible after a positive COVID-19 test and within 10 days of symptom onset. The authorization allows for the distribution and emergency use of bamlanivimab, which is administered via a single intravenous infusion."This emergency authorization allows us to make bamlanivimab available as a COVID-19 treatment for recently diagnosed, high-risk patients — adding a valuable tool for doctors fighting the now-increasing burden of this global pandemic," David A. Ricks, Lilly's chairman and CEO, said. "The rapid development and availability of bamlanivimab could not have been achieved without the relentless work of our Lilly team, collaboration across the industry and the urgent work being done by the government to ensure appropriate allocation to patients who need it the most."The emergency use authorization is based on data from BLAZE-1, a randomized, double-blind, placebo-controlled Phase 2 study in patients with recently diagnosed mild to moderate COVID-19 in the outpatient setting. Patients treated with the drug showed reduced viral load and rates of symptoms and hospitalization, Lilly said in the statement. Infusion reactions and other allergic hypersensitivity events have been reported, Lilly said. The emergency use authorization includes a warning for hypersensitivity including anaphylaxis and infusion-related reactions.Lilly said the drug is not authorized for use in patients who are hospitalized due to COVID-19 or who require oxygen therapy due to COVID-19 or who require an increase in baseline oxygen flow rate due to COVID-19 in those on chronic oxygen therapy due to underlying non-COVID-19 related comorbidity."The BLAZE-1 data show bamlanivimab, when given early in the disease course, may help patients clear the virus and reduce COVID-related hospitalizations, supporting our belief that neutralizing antibodies can be an important therapeutic option for patients fighting this virus," Daniel Skovronsky, M.D., Ph.D., Lilly's chief scientific officer and president of Lilly Research Laboratories, said. "We're proud of the speed with which we have been able to bring patients this therapy specifically designed to treat COVID-19. We thank those who have contributed to this medical advancement, particularly the clinical trial investigators and participants around the country." This article was written by Bob Blake for WRTV. 2906

AURORA, Colo. -- Just as hundreds of restaurants are being forced to close down indoor dining, yet again, In-N-Out Burger made its debut in Colorado on Friday.Hundreds waited in line for hours to get a burger from the California-based fast-food chain.“It’s just a journey today,” said Charly, who came to relieve her dad who waited for three hours, but then had to go to work without making it to the front of the line.“Three or four hours wasn’t unexpected,” said Bob Fischer. “So, it’s definitely worth the wait.”Whether it was worth the wait depends on who you asked.But is it worth it? “No,” said Charly. “I don’t even eat beef. I’m just here for (my sister) and my dad.”In-N-Out’s arrival in Colorado comes at the most ill-timed or opportune moment, depending on your perspective.“I ordered about five cheeseburgers and five animal fries,” said one In-N-Out fan who did not wish to be identified. “It’s all about the uniqueness of the secret menu,” Fischer said.“I grew up in California, so we were always eating it,” said Maddie Duncan.Just around the corner, at the mom-and-pop NGL Burgers, owner Jesus Pulido is preparing to close to indoor dining yet again.“Tomorrow it’s back to take-out only or I can put some tables outside,” Pulido said.After 16 years in business in Aurora, Pulido, who’s also from California, certainly has his fans, too.“The food speaks for itself,” said an NGL regular named Zeke.“I grew up in L.A. There’s char-broiled burger places everywhere,” said Juan Lopez. “And this is exactly the same way.”Lopez says Pulido’s prices are right on the money.“If you’re going to let me pick for lunch, I’m going to come here because this is a better deal,” Lopez said.The question is – what kind of dent will In-N-Out, coupled with another COVID-19 shutdown put in Pulido’s business.He, for one, believes he will survive.“In-N-Out, that’s going to hurt me a little bit, you know? But I have my own customers,” Pulido said. “They want to go over there, whatever.”“To me – it’s important to keep these guys going,” Lopez said. “They know me so when I come here, you get the feeling of family and community.”This article was written by Russell Haythorn for KMGH. 2202