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LINKSFIND YOUR POLLING PLACE TRACK YOUR BALLOT ELECTION GUIDESAN DIEGO (KGTV) -- In the March primary election, election officials in California had to disqualify 102,428 mail-in ballots, or about 1.5 percent.So how do you ensure your vote gets counted?The very first step is to make sure you are registered to vote. Voters in San Diego County can do so at sdvote.com. Californians in other counties should visit vote.ca.gov.The deadline to register is October 19.The second thing you want to do is make a plan for how you will vote, either by mail or in-person.“Our recommendation, particularly with the pandemic, is to vote by mail in this upcoming election,” said San Diego County Registrar of Voters Michael Vu.Because of the pandemic, election officials are sending mail-in ballots to every active, registered voter in California for the first time in state history. As long as you’re registered by October 19, you’ll get one, Vu said.When you’re making your selections, “clearly mark that ballot, similar to when you’re going to a polling place with an ink pen. Black or blue is preferred,” Vu said.Once filled out, seal the ballot in the pre-paid return envelope and sign the back. Seriously. Don’t forget.Missing or mismatched signatures, meaning the signature on the ballot doesn’t match the one on file, are the second most common reason mail ballots get disqualified.The number one reason is that they’re sent back too late. Ballots must be postmarked on or before Election Day, November 3.“Fill it out at your leisure. But send it back with plenty of time just to make sure that it's postmarked on or before Election Day in order to count,” said California Secretary of State Alex Padilla.You can return the ballot to the post office or a mail-ballot drop-off location. There are 126 drop-off locations in San Diego County. You can also drop it off at a polling place.If mail ballots aren’t your thing, you can still vote in-person at the polls. Every polling location will open up to three days early, on October 31.Voters can also cast an in-person ballot at the San Diego County Registrar of Voters office as of October 5. The office is open from 8 a.m. until 5 p.m. Monday through Friday.“If you choose to vote in person. Don't wait for the last day. Go the very first day that voting locations are open,” Secretary Padilla said.If you’re going to the polls in person, make sure to double check the location. Your assigned polling place has probably changed from previous elections.In San Diego County, they’ve gone from 1,548 locations last cycle to just 235, but election workers are bringing in larger venues, like Viejas Arena and the Convention Center.“They’re strategically located. No less than 2,000 square feet in the majority of these locations to allow for physical distancing,” Vu said.Vu said by shrinking the number of polling locations, they’re able to have the polls open for four days rather than one, which he hopes will help spread out voters and mitigate the risk of the virus.For the first time statewide, you can sign up to track your ballot through a new tool called Where’s My Ballot? The system will send text alerts and emails when your ballot is mailed, when election officials receive it, when it’s been counted, and if there are any issues with your ballot that can be corrected, such as a missing signature.“Do a little bit of homework, know the process. Decide how you're going to vote and do it early,” Padilla said.A record 72 percent of California ballots were cast by mail in the March primary, so election officials are used to the process. But they’re still urging voters to have patience for a long count. Registrar Vu said he plans to take the full 30 days to certify the results. 3743

Less parental warmth and a more harsh work environment affect how aggressive children become and whether they lack empathy and a moral compass, according to a new study.Researchers at the University of Michigan, University of Pennsylvania and Michigan State University studied 227 pairs of identical twins. They analyzed differences in the parenting that each twin experienced to determine whether the differences predicted the emergence of antisocial behaviors.The study found that the twin who experienced harsher treatment and less emotional warmth had a greater chance of showing aggression and a lack of empathy and moral compass.These characteristics are known as callous-unemotional traits."The study convincingly shows that parenting—and not just genes—contributes to the development of risky callous-unemotional traits," said Luke Hyde, U-M associate professor of psychology. "Because identical twins have the same DNA, we can be more sure that the differences in parenting the twins received affects the development of these traits."Parents of the twins completed a 50-item questionnaire about the home environment, establishing their harshness and warmth levels.The work, published in the Journal of the American Academy of Child and Adolescent Psychiatry, is the latest in a series of studies from Penn's Rebecca Waller, assistant professor of psychology, and colleagues using observation to assess a variety of aspects of parenting. "Some of the early work on callous-unemotional traits focused on their biological bases, like genetics and the brain, making the argument that these traits develop regardless of what is happening in a child's environment, that parenting doesn't matter," said Waller, lead author of the current study. "We felt there must be something we could change in the environment that might prevent a susceptible child from going down the pathway to more severe antisocial behavior."Waller says a potential next step to turn these findings into interventions for families trying to prevent a child from developing these traits or to improve troubling behaviors. "From a real-world standpoint, creating interventions that work practically and are actually able to change behaviors in different types of families is complicated," she said. "But these results show that small differences in how parents care for their children matters. Our focus now is on adapting already-successful parenting programs to include specific interventions focused on callous-unemotional traits as well."For more information, click here. 2577

LA JOLLA, Calif. (KGTV) — La Jolla's Children's Pool has closed for the season to make way for seal pupping season on the beach's shore.The annual closure went into effect Sunday and will extend until May 15, 2020. During the closure, visitors will not be permitted to use the sheltered beach and, much like the rest of the year, be discouraged from getting too close to the seals.The closure is meant to give harbor seals a safe area to birth and wean their young for the season. Park rangers and lifeguards will monitor the beach to make sure both the public and seals are kept safe.RELATED:Coastal Commission approves permit to protect seals during pupping seasonChildren's Pool sea wall could be deteriorating faster, historical architect saysCity officials began closing the beach for pupping season in 2014, after environmental activists voiced concerns over the safety of young seals born and cared for at the Children's Pool. For years afterward, the city was tied up in litigation over the beach and ability to close it to the public. Critics argued the closures violated the state Coastal Act and the federal Marine Mammal Protection Act.In June 2018, a state appeals court ruled in favor of the city and the ability to close the beach for the season. A year later, the California Coastal Commission renewed a 10-year permit to close the Children's Pool to human access during pupping season.Critics have threatened to take the matter to the state Supreme Court, but the matter hasn't moved that far as of yet.The Children's Pool was opened in 1932 as a space for inexperienced swimmers to enjoy the water safely behind a seawall. Seals started convening on the beach in the 1990s and have since used it for pupping season.The California Coastal Commission has said they believe the water is unsafe due to bacteria levels from the seals and their excrement and encourage visitors to find somewhere else to swim.Officials have also been forced to post signs warning visitors to keep their distance from seals year-round, as the animals could feel threatened if humans come to close to them or their young. 2122

LEMON GROVE, Calif. (KGTV) — A local favorite among beer fans, Amplified Ale Works is expanding its brews eastward.The brewery announced plans to open a production facility in Lemon Grove, inside the historic Sonka Brothers general store building at 3308 Main St., most recently occupied by Lemon Grove Bakery.“We’re looking to open up to our fans, the craft beer community, local music supporters, and Lemon Grove residents the opportunity to have a true investment in a business they can also have an emotional investment in,” Alex Pierson, owner of Amplified Ale Works, said in a release.RELATED: Craft beer scene brewing in Chula VistaAmplified says the facility will have the capacity to brew up to 10,000 barrels annually, which about five times its current production level. The brewery hopes the facility fulfills needs of future Amplified beer gardens and canning.The location, Amplified's third beer garden, will also host live music and food trucks.To help fund the new location, the brewery is asking for crowdfunding, similar to a GoFundMe or Kickstarter campaign. “We wanted to offer a real way for our fans and community to be a part of what they have helped create over the past decade and be an integral part of our future as well,” said Pierson.RELATED: San Diego craft beer study shows craft brewery, economic impact growthPierson added that the brewery intends to institute an Employee Stock Ownership Plan, which offers equity and shares of the business to long-term employees. The investment term may sound familiar to some. In 2017, San Diego brewery Modern Times became the first employee-owned brewery in California after it adopted an ESO model.Amplified Ale Works has locations in Miramar, Pacific Beach, and East Village. 1757

Last year's seasonal flu vaccine effectiveness was just 42%, the US Centers for Disease Control and Prevention estimated. Even if vaccinated, then, people had inadequate protection against the flu.This limited effectiveness was due to a mutation that occurred in the influenza A (H3N2) vaccine strain, according to a new study published Monday in the journal Proceedings of the National Academy of Sciences. This vaccine mutation resulted from an egg-based manufacturing process commonly used today.This year's flu vaccine may also be imperfect, said Scott Hensley, author of the new study and an associate professor at the University of Pennsylvania. Add to that, he said, "this could end up being a pretty bad flu season."Still, he said, "our best protection" against severe illness is getting vaccinated with the flu shot we have today.Finding answersEach year before flu season begins, a vaccine is made based on whichever virus strains are expected to circulate. The selected seed strains are distributed to vaccine manufacturers which then produce their formulations and make them available to health care professionals before the season begins.During the 2015-16 season, vaccine effectiveness was 47%, while for the previous 2014-15 season, effectiveness was just 19%, according to the CDC. While the overall effectiveness of last season's vaccine was 42%, it was only 34% effective against the H3N2 viruses that dominated the season.Vaccine effectiveness varies based on how well it matches the circulating virus strains. Sometimes, a vaccine corresponds to the predominant virus yet its effectiveness is still not what scientists would expect. Trying to understand which element of the vaccine failed is difficult.Hensley and his team began their investigation of last year's vaccine by looking at the seed strains that had been distributed to vaccine manufacturers. These seed strains had been propagated in chicken eggs, the common method used today."The sequences of these viruses are available and when we did an alignment to see what the sequence of these vaccines were compared to the viruses that were circulating, it became very obvious that there was this mutation," said Hensley.To see the effects of the mutation, the team next looked at how the immune systems of both animals and humans who'd been inoculated with an egg-based flu vaccine responded to the actual circulating viruses.The antibodies -- immune system proteins that fight invading pathogens -- elicited in both animals and humans failed to bind to and neutralize the flu viruses, Hensley and his colleagues found.While most vaccines in the United States are made in chicken eggs, a small fraction are produced in insects or mammalian cells, Hensley explained. (These are given to people with egg allergies.) He and his team compared immune responses in animals and humans who had received a cell-based vaccine -- in this case, Flublok made by Protein Sciences Corporation."And we found both animals and humans receiving that (cell-based) vaccine had superior antibody responses that could bind and neutralize these circulating H3N2 strains," said Hensley.Making a better vaccine"Most of the infrastructure to produce vaccines in the US is based on chicken eggs," said Hensley. There are good reasons for this, including the fact that egg-based propagation allows manufacturers to quickly produce large quantities of vaccine.While egg adaptations have always been a problem, beginning last year it had become a "huge problem," said Hensley. "As soon as you try to grow this virus in eggs, within a few hours, the virus will acquire this kind of mutation."This is not an easy problem to fix, he said. To produce vaccines in cells means "a very expensive process for companies to just change their overall manufacturing process," Hensley explained. "You can't really do that on the drop of a dime."Meanwhile, the same seed strains used last year are being used this year to make the current vaccine, said Hensley."This year may be especially difficult because, in addition to this egg adaptive mutation which was present last year, there's indication that the H3N2 viruses are actually evolving," said Hensley.Not only will the vaccine be a mismatch with the actual circulating viruses due to egg adaptation but the vaccine could also be a mismatch due to unexpected viral evolution.What kind of flu season is ahead?It's too early to speculate which viruses will become dominant in the United States over the course of the coming flu season, said Hensley, "but it's starting to look like it will be H3 viruses." H3 viruses are influenza A viruses."There are the A group of viruses and the B groups," said Dr. William Schaffner, an infectious disease specialist at Vanderbilt University. "The A groups are the ones that usually are responsible for large epidemics ... whereas the B flu strains usually smolder along. They always cause illness -- it can be just as severe as the A strains -- but they don't produce large outbreaks."Though last year's vaccine was mostly ineffective in thwarting the flu, it still prevented nearly 30% of hospitalizations that might have resulted, according to CDC calculations. For older adults, that rate was even higher, at 37%. Plus, the vaccine reduced outpatient visits by 42% last season.The CDC advises everyone 6 months and older to get a flu shot, as only injectable flu vaccines are recommended. More than 130 million doses of flu vaccine have been distributed so far this year and flu activity is still low across the nation.It's still early days, but experts believe we may be facing a tough season, and not only because of vaccine concerns.The reason?Australia had a tough flu season this year, with a total of 215,280 laboratory-confirmed cases and 504 flu-associated deaths reported to its National Notifiable Diseases Surveillance System as of October 13, government data show. According to a surveillance system report, adults over the age of 80 and children between 5 and 9 years old have been most affected."In general, we get in our season what the Southern Hemisphere got in the season immediately preceding us," Dr. Anthony Fauci, director of the United States' National Institute of Allergy and Infectious Diseases, said in an interview last month.An "intelligent guess," therefore, is that the Northern Hemisphere, like the Southern Hemisphere, will likely battle more cases of the viral infection, he said, though "with influenza, it is never 100%.""If H3N2 viruses dominate the US flu season again this year, vaccine effectiveness will likely be moderate to low again," said Hensley.Still, he said, everyone should get their annual flu shot."The other components of the vaccine, like H1N1 and influenza B, will likely provide excellent protection," said Hensley. "The vaccine will also likely prevent severe disease and death caused by H3N2 viruses, even though this component of the vaccine is mismatched."  6969

来源：资阳报