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Juul Labs will immediately stop online sales of mint Juulpods and will stop accepting orders for them from retailers, Juul Labs' CEO K.C. Crosthwaite 162
It is a truth universally acknowledged that middle seats on airplanes are the worst.Being awkwardly sandwiched in between two people while fighting for elbow room is the bane of most passengers. Now a new design might actually make people want the middle seat -- or at least make the 296

It’s hard to regard Ellie as a menace.When Greg Manteufel is frustrated or feeling down, she sits by him. At night, she sleeps under his covers. At dinner, she’s there next to him, knowing he’ll throw something her way. She belies the stereotype of the vicious pit bull.“We love her like she’s our daughter,” he said of the dog.And yet, Ellie may be the reason Manteufel nearly died.Gravely ill, he lost parts of his arms and legs, as well as the skin of his nose and part of his upper lip. The cause was capnocytophaga (cap-noh-seye-TOE’-fah-gah), a germ from Ellie’s mouth or from another dog he encountered.Capnocytophaga is commonly found in the saliva of cats and dogs and almost never leads to people getting sick, unless the person has a compromised immune system. But Manteufel was perfectly healthy. In fact, he doesn’t think he’d ever used his health insurance before he fell ill.The case is extremely rare and doctors at his hospital, Froedtert & the Medical College of Wisconsin, had no explanation for why he got so sick. But over the last 10 years there have been at least five other healthy people who have had severe reactions to the germ. A team of researchers connected with Harvard Medical School has developed a theory on why — a gene change in all the victims.And their finding means doctors can’t rule out the capnocytophaga bacteria could strike Manteufel and other victims again.___Greg Manteufel thought he was getting the flu in June of 2018. He had a fever, vomiting and diarrhea. But when he started getting confused, his family took him to the hospital.Doctors did blood cultures and found capnocytophaga, which caused sepsis, a severe blood infection that led to his blood pressure dropping and many of his organs shutting down.“Do what you have to,” he told the doctors.He had so much to live for — foremost, his wife of 16 years, Dawn, and 26-year-old son, Mike. He was just starting to get really good at his day job, painting houses. He cherished his Harley Davidson Electric Glide. He was in the middle of fixing up his ’66 El Camino. And of course there was Ellie, the pup.And so he persisted, through more than 20 surgeries, including amputations of his left and right arms just below the elbow, and legs through the middle of the knee.His wife and son stayed optimistic, because he was.“Greg said he didn’t come this far to lay down and let this beat him,” Dawn Manteufel said.He was out of the in-patient rehab unit in about two weeks, learning to move from his wheelchair to the bed, toilet and car. The usual stay is three to four weeks, said Dr. David Del Toro, medical director for the inpatient rehab unit at Froedtert.Manteufel made similar quick advances using his arm prosthetics and leg prosthetics.“He does not seem like any other patient I’ve met before,” Del Toro said. “He’s just, you know, full speed ahead.”Meanwhile, researchers at Brigham and Women’s Hospital in Boston, connected to Harvard Medical School, as well as Dana-Farber Cancer Institute and Beth Israel Deaconess Medical Center had been investigating cases like his.The team has done genetic testing on five otherwise healthy people who suffered capnocytophaga infections to see if they could find anything in common. They discovered all had a gene connected to the immune system that was working differently — a genetic variant.“It was a really thrilling moment,” said Elizabeth Fieg, a genetic counselor at Brigham and Women’s Hospital. “The stakes are so high with these cases and the patients have gone through so much.”They believe it makes those people more susceptible to developing severe medical problems from capnocytophaga. But they are also trying to determine if there are other risk factors.Of the five in the study, three survived with amputations and two did not. Fieg hopes their research can determine why some did not survive.She also hopes if their theory is confirmed, it will help diagnose cases faster, and perhaps save lives and limbs.That’s why Greg Manteufel jumped at the chance to take part when he was approached in August.Researchers need to gather more evidence, but hope to publish their study in the next year to 18 months.___Manteufel’s life now includes frequent occupational therapy appointments to perfect his use of arm prosthetics — the kind with metal moveable hooks at the end. He’s using a fork regularly and he’s now working on picking up the TV remote, opening doorknobs, cutting vegetables and doing the dishes.He’s using shortened leg prosthetics, called stubbies, to get his body conditioned to eventually use to full-sized ones. Those are expected to arrive any day.Plastic surgeons plan another surgery to perfect his nose. They’ve already moved skin from his forehead there. It looks oversized now, but it will eventually fit in with the rest of his face.He plans to get his car revamped so he can drive with prosthetics. He wants to get a special pole so he can go fishing again. He is even considering going back to work painting.He’s also become less quiet and a lot more outgoing. “Now everybody I see wants to hear something or talk to me. I tell them a 15-minute story about what happened. They probably want me to leave, you know,” he said, chuckling.Ellie’s often by his side.“She loves kids. She loves puppies. Other dogs,” Manteufel said.As harmless as she seems, she may have capnocytophaga germ.The results of Manteufel’s genetic tests are expected in three to four months. Fieg said people with the gene variant are at increased risk for recurrent capnocytophaga or other infections in the future.While Manteufel doesn’t like the sound of that, he said Ellie’s accidentally scratched him since he’s been home and even licked his mouth. He’s been fine.And even if he does have the gene variant, he said, it changes nothing.“We didn’t even bother testing her,” said Manteufel. “We weren’t going to get rid of her if it was her that caused it anyway.”“We just love her to death.” 5972
It’s a morning routine unlike any other.With every inhale and exhale Brother Sage starts feeling the flow.Once this spiritual healer centers his chi, he then decides to drink his own pee.“So, this is the water of life,” Brother Sage said while holding a bottle of his urine. “Some people know it as the water of auspiciousness.”Brother Sage is a believer in urine therapy and has practiced this technique for decades, using urine to wash his eyes, clean his feet and clear out his sinuses.He calls urine therapy a cleansing for the mind, body and spirit. Now he’s sharing this ideology with others.About once a week at the Boulder Public Library the Urine Therapy Group of Colorado meets up, with members discussing how drinking their pee has cured them from all sorts of ailments.“It is beneficial in any situation,” said Indira Bhatt Gupta. “If you have stomachache, drink that — it goes away. So many benefits.” For some, the benefits aren't just physical, they’re mental, too.“I feel like it cured my depression,” Dylan Flora said.When asked how long it took to feel the change, Flora replied, “instantly.”Urine therapy has been practiced in ancient Eastern cultures for thousands of years and now Western doctors are trying to clear up any misconceptions about believed medicinal benefits from ingesting urine.“It is entirely possible to get chlamydia or gonorrhea of the mouth from drinking someone’s urine if they have those diseases,” said Dr. James Wilk of UCHealth in Colorado.Wilk claims drinking urine can be dangerous, saying pee belongs in a toilet and not in your mouth.“Actual scientific studies failed to show any kind of benefit,” Wilk said. “There’s nothing, except for exercise, that is a panacea that works for so many diseases.”Brother Sage, however, is questioning modern science. “If you have a bee sting, a wasp sting, you stepped on something that's going to start bleeding," he said, "(urine) switches the pH to alkaline so the body starts to heal faster." 1995
Jefferson County Judge Jeff Branick confirmed that thousands of his county's residents remain evacuated on Thursday following a fire and explosion at an industrial plant Port Neches, Texas. The fire remained active on Thursday, one day after a pair of explosions at the plant rocked the town of Port Neches. The explosions could be felt from up to 30 miles away, and blew out windows near the plant. Branick said that the situation was improving on Thursday, but that "doesn't mean we shouldn't exercise great caution."A 4-mile radius was evacuated from the plant amid fears of further explosions. Branick told reporters on Thursday that officials plan to visit the site of the plant on Friday as residents spent a second night forced from their homes. Branick said that the fire at the plant wasn't being controlled, but officials were working to contain the inferno. "The firefighters are doing an incredible job for their community," Branick told reporters. Despite the size and scope of the explosions, only three people suffered injuries, and no fatalities were reported.Officials continue to monitor the air quality near the plant. The real-time air monitoring results continue to show no actionable levels above state and federal regulatory guidelines, officials said. TPC Group operates the manufacturing plant. The plant processes C4 hydrocarbons, producing butadiene and raffinate and stores MTBE. The incident began at a tank with finished butadiene. Butadiene is used in the production of synthetic rubber used for tires and automobile hoses.The plant employs 175 people, and roughly 30 were on site at the time of the first explosion. The plant makes products for chemical and petroleum companies.All personnel are fully accounted for, TPC Group said. 1776
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