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While Election Day is still 19 days away, voters were already forced to make a decision on Thursday: Donald Trump or Joe Biden.While the decision will not show up on an official ballot or election, the choice Americans were forced to make was on which presidential town hall to watch. While having debates on competing networks might have made things challenging for swing voters, there are not many undecided voters left, according to polls. In a national poll released by "The Hill" yesterday, the survey found that 7% of voters remain undecided. On one network, Joe Biden calmy responded to questions from a socially-distanced audience in Pennsylvania. Meanwhile, President Donald Trump sparred with NBC News host Savannah Guthrie in a competing town hall there.The dueling town halls were held in lieu of a traditional town hall debate. The debate was scrapped after the Commission on Presidential Debates said that tonight’s debate would be held virtually. Trump opted out of a virtual debate, prompting Biden to schedule a forum on ABC News. Yesterday, Trump announced he too would hold a network-televised debate, this time on the NBC family of networks.Trump and Biden plan on debating next week in person for the final time. Biden said he would like to see Trump tested for the coronavirus at the next debate.“Yeah," Biden said when asked if Trump should be tested. "By the way, before I came up here, I took another test, I've been taking it every day, the deep test, you know, the one, they go in both [noses]. Because I wanted to be able to — if I had not passed that test, I didn't want to come here and not expose anybody."White House press secretary Kayleigh McEnany originally stated that Trump was tested multiple times a day. But Trump has acknowledged that he wasn’t tested every day, and said during Thursday’s town hall he was unsure when his last negative test was before announced he was infected with the coronavirus on Oct. 2.“I don't know, I don't even remember,” Trump said. “I test all the time. I can tell you this. After the debate, like, I guess, a day or so, I think it was Thursday evening, maybe even late Thursday evening, I tested positive. That's when I first found out,While Biden answered questions on tax policy, Trump responded to a New York Times story on his personal taxes, and was pressed on details that he reportedly owes 0 million in taxes in the coming years. "I'm treated very badly by the IRS,” Trump said. “They treat me very, very badly. You have people in there from previous administrations. They treat me very badly. But we're under audit. It's very routine in many ways. But we're under audit. They like to change the game, change the rules, do everything,"Biden was pushed on whether he would raise taxes amid a pandemic and higher unemployment.“When I said the Trump tax cuts, about .3 trillion of the trillion in his tax cuts went to the top one tenth of 1%,” Biden said. “That’s what I’m talking about eliminating. Not all the tax cuts that are out there.” 3033
With a coronavirus vaccine still months off, companies are rushing to test what may be the next best thing: drugs that deliver antibodies to fight the virus right away, without having to train the immune system to make them.Antibodies are proteins the body makes when an infection occurs; they attach to a virus and help it be eliminated. Vaccines work by tricking the body into thinking there’s an infection so it makes antibodies and remembers how to do that if the real bug turns up.But it can take a month or two after vaccination or infection for the most effective antibodies to form. The experimental drugs shortcut that process by giving concentrated versions of specific ones that worked best against the coronavirus in lab and animal tests.“A vaccine takes time to work, to force the development of antibodies. But when you give an antibody, you get immediate protection,” said University of North Carolina virologist Dr. Myron Cohen. “If we can generate them in large concentrations, in big vats in an antibody factory ... we can kind of bypass the immune system.”These drugs are believed to last for a month or more and could give quick, temporary immunity to people at high risk of infection, such as health workers and housemates of someone with COVID-19. If they proved effective and if a vaccine doesn’t materialize or protect as hoped, the drugs might eventually be considered for wider use, perhaps for teachers or other groups.They’re also being tested as treatments, to help the immune system and prevent severe symptoms or death.“The hope there is to target people who are in the first week of their illness and that we can treat them with the antibody and prevent them from getting sick,” said Dr. Marshall Lyon, an infectious disease specialist helping to test one such drug at Emory University in Atlanta.Having such a tool “would be a really momentous thing in our fight against COVID,” Cohen said.Vaccines are seen as a key to controlling the virus, which has been confirmed to have infected more than 20 million people worldwide and killed more than 738,000. Several companies are racing to develop vaccines, but the results of the large final tests needed to evaluate them are months away.The antibody drugs are “very promising” and, in contrast, could be available “fairly soon,” said Dr. Janet Woodcock, a U.S. Food and Drug Administration official who is leading government efforts to speed COVID-19 therapies. Key studies are underway and some answers should come by early fall.One company, Eli Lilly, has already started manufacturing its antibody drug, betting that studies now underway will give positive results.“Our goal is to get something out as soon as possible” and to have hundreds of thousands of doses ready by fall, said Lilly’s chief scientific officer, Dr. Daniel Skovronsky.Another company that developed an antibody drug cocktail against Ebola — Regeneron Pharmaceuticals Inc. — now is testing one for coronavirus.“The success with our Ebola program gives us some confidence that we can potentially do this again,” said Christos Kyratsous, a Regeneron microbiologist who helped lead that work.Regeneron’s drug uses two antibodies to enhance chances the drug will work even if the virus evolves to evade action by one.Lilly is testing two different, single-antibody drugs — one with the Canadian company AbCellera and another with a Chinese company, Junshi Biosciences. In July, Junshi said no safety concerns emerged in 40 healthy people who tried it and that larger studies were getting underway.Others working on antibody drugs include Amgen and Adaptive Biotechnologies. The Singapore biotech company Tychan Pte Ltd. also is testing an antibody drug and has similar products in development for Zika virus and yellow fever.“I’m cautiously optimistic” about the drugs, said the nation’s top infectious diseases expert, Dr. Anthony Fauci. “I’m heartened by the experience that we had with Ebola,” where the drugs proved effective.What could go wrong?— The antibodies may not reach all of the places in the body where they need to act, such as deep in the lungs. All the antibody drugs are given through an IV and must make their way through the bloodstream to wherever they’re needed.— The virus might mutate to avoid the antibody — the reason Regeneron is testing a two-antibody combo that binds to the virus in different places to help prevent its escape.Skovronsky said Lilly stuck with one antibody because manufacturing capacity would essentially be cut in half to make two, and “you will have less doses available.” If a single antibody works, “we can treat twice as many people,” he said.— The antibodies might not last long enough. If they fade within a month, it’s still OK for treatment since COVID-19 illness usually resolves in that time. But for prevention, it may not be practical to give infusions more often than every month or two.A San Francisco company, Vir Biotechnology Inc., says it has engineered antibodies to last longer than they usually do to avoid this problem. GlaxoSmithKline has invested 0 million in Vir to test them.Giving a higher dose also may help. If half of antibodies disappear after a month, “if you give twice as much, you will have two months’ protection,” Lilly’s Skovronsky said.— The big fear: Antibodies may do the opposite of what’s hoped and actually enhance the virus’s ability to get into cells or stimulate the immune system in a way that makes people sicker. It’s a theoretical concern that hasn’t been seen in testing so far, but large, definitive experiments are needed to prove safety.“As best as we can tell, the antibodies are helpful,” Lyon said.___Marilynn Marchione can be followed on Twitter: @MMarchioneAP___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. 5919

When Dr. Harold Bornstein described in hyperbolic prose then-candidate Donald Trump's health in 2015, the language he used was eerily similar to the style preferred by his patient.It turns out the patient himself wrote it, according to Bornstein."He dictated that whole letter. I didn't write that letter," Bornstein told CNN on Tuesday. "I just made it up as I went along."The admission is an about face from his answer more than two years when the letter was released and answers one of the lingering questions about the last presidential election. The letter thrust the eccentric Bornstein, with his shoulder-length hair and round eyeglasses, into public view."His physical strength and stamina are extraordinary," he crowed in the letter, which was released by Trump's campaign in December 2015. "If elected, Mr. Trump, I can state unequivocally, will be the healthiest individual ever elected to the presidency."The missive didn't offer much medical evidence for those claims beyond citing a blood pressure of 110/65, described by Bornstein as "astonishingly excellent." It claimed Trump had lost 15 pounds over the preceding year. And it described his cardiovascular health as "excellent."The White House didn't respond to a request for comment about Bornstein's claim.Later, as questions mounted over the health both of Trump and his rival Hillary Clinton, Bornstein offered a more businesslike assessment, listing things such as Trump's height, weight and prescription medications.He later told CNN's Drew Griffin he'd dashed off the first letter as he was seeing patients."I was just rushed for time," he said in September 2016. "I had people to see."He insisted then that the words were his own."Did I really write that letter? Yeah," he said.Now, as Bornstein re-enters the spotlight claiming Trump's ex-bodyguard Keith Schiller robbed his office when Schiller retrieved Trump's medical records, the story behind the letter is becoming clearer."That's black humor, that letter. That's my sense of humor," he said. "It's like the movie 'Fargo': It takes the truth and moves it in a different direction."He said Trump read out the language as Bornstein and his wife were driving across Central Park."(Trump) dictated the letter and I would tell him what he couldn't put in there," he said. "They came to pick up their letter at 4 o'clock or something." 2369
When Sen. Bernie Sanders did this in 2013, he did it alone.On Wednesday, nearly four years later, Sanders introduced a new "Medicare for all" health care bill with a third of the Senate Democratic caucus by his side.Flanked at first by New York Sen. Kirsten Gillibrand and Connecticut Sen. Richard Blumenthal, Sanders called the costs of the current system "insane and unaffordable," promising that the average family would benefit financially under his plan "because you will no longer be writing checks to private insurance companies."For those whose taxes would go up, he added, "that expense will be more than offset by the money are you are saving with the elimination of private insurance costs." 710
When a Minnesota teacher learned that her school's custodian was in dire need of a new kidney, she didn't hesitate to step up to the plate.According to the Minneapolis Star Tribune and CNN, teacher Erin Durga and custodian Part Mertens have been co-workers at Kimball Elementary School in Kimball, Minnesota, for nine years.The two were well acquainted — they often exchanged pleasantries in the hall, and Durga's children attended a daycare ran by Merten's wife.Recently, Mertens had been leaving school early three days a week to attend dialysis treatments. Earlier this year, the school organized a "Hats for Pat" fundraiser to help pay for his treatments. But school officials didn't realize how dire Mertens' situation was until his daughter posted a plea for help on Facebook.According to Mertens' daughter, Kayla Matten, none of her fathers' relatives was a match for a kidney transplant."We are now in the process of trying to find someone with an O blood type and someone who is willing to donate their kidney," she wrote, according to CNN.When Durga saw the post, she didn't hesitate. She knew she wanted to donate her kidney to a co-worker in need."Why wouldn't you [do it]?" she told the Star Tribune.In late spring, Durga and Mertens found out they were a match."It brought a few tears to my eyes," Mertens told the Star Tribune. "I'm not much for expressing myself."Despite the COVID-19 pandemic, the two underwent the transplant surgery on July 3. Months later, Mertens is doing well, and the Star Tribune reports that he is no longer "tethered" to dialysis treatments."I can live again," Mertens told the Star Tribune. 1642
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