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WASHINGTON, April 11 (Xinhua) -- In the first clinical trial of gene therapy for treatment of intractable pain, U.S. researchers from the University of Michigan's Department of Neurology observed that the treatment appears to be able to provide substantial pain relief.In a study published online in the Annals of Neurology and seen on Monday, the researchers showed that the novel agent NP2 is safe and well-tolerated. In addition, measures of pain in the treated patients suggested that NP2 may provide a substantial analgesic effect.NP2 is a gene transfer vector that expresses the naturally- occurring opioid peptide enkephalin. In preclinical work in animals, David Fink, chair of the Department of Neurology, and his coworkers had demonstrated that injection of NP2 into the skin reduces pain in models of pain caused by nerve damage, inflammation or cancer.In the clinical trial, 10 patients with unrelenting pain caused by cancer were injected with the gene transfer agent in the area of skin related to the location of pain."The concept underlying this therapeutic approach is that injection of NP2 into the skin results in uptake into the nervous system and the production and release of a pain-relieving chemical in a controlled site in the pain pathway," says Fink. "In the study, patients who received the low dose of vector showed little reduction in pain; patients receiving the higher doses showed a greater than 80 percent reduction in pain over the course of four weeks following treatment."Fink's laboratory has been working on the use of modified herpes simplex virus-based vectors that are taken up by sensory nerves following skin injection to develop therapies for diseases of the nervous system for more than 20 years. Patents related to this technology have been exclusively licensed by Diamyd Medical, a publicly-traded Swedish biotechnology company that sponsored the trial, and the human-grade vector NP2 was produced by Diamyd, Inc, the U.S. subsidiary of Diamyd Medical.A phase 2 trial to compare NP2 to a placebo control has already been initiated under sponsorship from Diamyd.

MOSCOW, May 13 (Xinhua) -- The main and backup crews that will fly to the International Space Station in June have passed preflight tests and are ready for space travel, the Russian Cosmonauts Training Center said Friday.The main crew includes Russian cosmonaut Sergei Volkov, Japanese astronaut Satoshi Furukawa and American astronaut Michael Fossuma.A Russian spaceship Soyuz TMA-02M will send the crew to the space station on June 8, Interfax news agency reported.The backup crew includes members from Russia, the Netherlands and the United States.The crews were tested on the various emergency situations they could face during the flight.Next Monday, the commission will make a final choice of crewmembers for the launch.The crew will spend 161 days in orbit and conduct three space walks.

BEIJING, Jan. 21 (Xinhua) -- China's State Council, or Cabinet, Friday published the newly adopted regulations on expropriation of houses on state-owned land and compensation.The new rules, which took effect upon the issuing, took the place of the 2001 regulations on administration of the housing demolition and relocation in cities.The new rules specifically stated that neither violence or coercion may be used to force homeowners to leave. Nor could measures, such as illegally cutting water and power supplies, be used in relocation work.The new rules also banned land developers' involvement in the demolition and relocation procedures, as well as demolition by local governments without court approval.Moreover, the new regulations ensured fair prices for homeowners by providing that compensation for expropriated homes should be no lower than the sum of the market price of similar properties at the time of an expropriation.The regulations were first reviewed at a State Council executive meeting in December 2007. Later, public opinion was twice sought in 2010 after revisions had been made to the regulations.An executive meeting of the State Council Wednesday gave in-principle approval to the regulations.

LUQA, Malta, Feb. 26 (Xinhua) -- A chartered plane of China Eastern Airlines carrying 272 Chinese evacuees from Libya left Malta for Shanghai on Saturday.The Airbus A330-300 plane took off at 8:20 p.m. local time ( 1920 GMT) from the Malta International Airport, to be followed shortly by another chartered plane of China Eastern Airlines with 278 Chinese evacuees on board.The 550-strong Chinese nationals from a Chinese construction company were among a total of 2,216 people who arrived by a ship from violence-torn Libya at the Grand Harbor in Valletta, capital of Malta, on Saturday.In addition to the 2,216 Chinese nationals, the ship chartered by the Chinese embassy in Malta also carried dozens of citizens of other countries.The vessel, which was the first Maltese ship chartered by the Chinese government to evacuate Chinese nationals, left Libya's Benghazi on Friday.Maltese Deputy Prime Minister and Foreign Minister Tonio Borg, who went aboard the ship, expressed gratitude to the Chinese government for helping to evacuate some Maltese nationals from Libya.Chinese Ambassador to Malta Zhang Keyuan also thanked the Maltese government for its cooperation in the evacuation of Chinese nationals.A 19-day-old baby was among the evacuated Chinese, said a source with the Chinese embassy.China Eastern Airlines will fly four planes every day to the Mediterranean island nation from Feb. 28 to March 10, as part of all-round airborne evacuation missions aimed at taking stranded Chinese citizens back home as soon as possible, according to information from an emergency meeting of the Civil Aviation Administration of China (CAAC) in Beijing on Saturday.

SAN FRANCISCO, April 22 (Xinhua) - Amazon's web-services disruption issues have not been completely resolved Friday morning, as some websites still in slow recovery.Amazon said in an update early Friday that meaningful progress has been made and is expected to continue over the next few hours.Reddit, a social news website, said on its homepage that "we are slowly getting our capacity back," and users may be able to log in if lucky. Some sites appeared to have recovered, including location-based social networking site Foursquare and HootSuite, an online brand management and social websites monitoring service.Amazon has not released the number of companies which have been disrupted by the outage and when the web-services will fully recover.The outage highlights risks of relying on public cloud service. Security and reliability have been experts' concerns on public could web-hosting service. Many Internet startups have been relying on the service to bring their costs down.Elastic Compute Cloud (EC2) is a central part of Amazon's cloud computing platform Amazon Web Services. It allows users to rent virtual computers on which to run their own computer applications. The European Space Agency, PBS and Ericsson are all among its cloud service customers.According to Amazon's Service Health Dashboard, errors began at 1:41 a.m. PDT Thursday in its datacenter in northern Virginia, saying "instance connectivity, latency and error rates."