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While scientists work to come up with a safe and effective COVID-19 vaccine, doctors across the country are watching closely. Many are helping guide their patients in making an informed decision about getting a vaccine."This was indeed a surprise to see that there would vaccines available by the 1st of November. It’s clearly an aspirational goal, because we all would like to see a safe and effective COVID-19 vaccine as soon as possible, but I think testing vaccines to make sure they’re safe and effective is of paramount importance," said Dr. Bali Pulendran, a microbiology and immunology professor at Stanford University.Dr. Pulendran says the process of developing a vaccine involves numerous steps, and scientists are getting closer to the end. Still, it's hard to put an end date on the third and final phase of a vaccine trial. This last phase determines whether the vaccine actually works."The way in which you can assess whether a vaccine works is to see how many of these people acquire the disease or become infected with COVID at some period of time," explained Dr. Pulendran.Phase three divides the trial participants into two groups. One group is given the vaccine, and the other is given a placebo."And then, you calculate the efficacy based on those numbers. So, if there were 200 people affected in the placebo group but there were only 100 people who were infected in the vaccinated group, then the efficacy is 50 percent" said Dr. Pulendran.The third phase is hard to time, as it depends on how quickly some of the trial participants become infected. If they live in areas where COVID-19 infection rates are higher, the phase will be completed faster.But there are some other ways to speed up the vaccine trial.Dr. Darria Long, an emergency room physician and clinical assistant professor at the University of Tennessee-Erlanger, says one way is by doing two of the phases at the same time. Another way is if officials prepare for the manufacturing and logistics side of producing the vaccine during the third phase of the trial."This is what we see the CDC saying is to get ready on the manufacturing and logistics side because even if you come up with the perfect target drug, making sure you can manufacture hundreds of millions and that you have the little glass vials that can keep it at the right temperature, those are all things that can be hang-ups,” said Dr. Long. “So, they're wanting to expedite that process, because the last thing you want is to say is we have the vaccine, but we can’t get it to people.”Dr. Long is already answering her patients' questions as news of a possible COVID-19 vaccine continues to be publicized."I do think a lot of people are wondering about this vaccine and it runs the gamut. There are those that say they really want the vaccine because they see it as this gateway to getting back to life as we know it," said Dr. Long.There are also those who are really concerned about the efficacy and safety of a COVID-19 vaccine. Doctors say a key piece in evaluating a vaccine when it does come out is the data surrounding it."The data that comes out in the public domain: is a particular vaccine efficacious? How effective is it what is the efficacy data? Is a particular vaccine safe? What are the side reactions? And they should talk with their physicians to ask each question. Ask doctors, ‘Could you tell me what the safety part of this vaccine is?" recommended Dr. Pulendran.And above all, doctors and scientists hope politics will stay out of the development of a COVID-19 vaccine in order to ease any concerns or hopes for a vaccine to be available as soon as possible. 3644

Will Smith will be back sitting on his throne as the Prince of Bel-Air when HBO Max streams the "Fresh Prince of Bel-Air" cast-reunion special on Thursday, Nov. 19.The trailer shows the former castmembers reminiscing about their time on the hit 1990s NBC comedy series at their time and the cultural impact it has had.There was also a tribute to the late actor James Avery, who played Uncle Phil, who died in 2014 due to open-heart surgery complications. 462

When adult film star Jessica Drake accused Donald Trump of sexual misconduct a month before the Presidential election, Trump said through a spokesperson that he didn't know the woman and had "no interest in ever knowing her."Less than a week later, a woman named Angel Ryan was listed in a secret settlement agreement negotiated by Trump's personal attorney as having "confidential information" about the then-Republican nominee.The two occurrences may appear unrelated. But there is a connection: Drake, the woman who accused Trump, and Ryan, the woman named in the non-disparagement agreement, are the same person, according to interviews and documents reviewed by CNN.The connection raises new questions about the circumstances surrounding the controversial agreement in which Trump attorney Michael Cohen sought to protect his longtime client and friend.The Wall Street Journal was first to report the news that Cohen paid adult film star Stephanie Clifford 0,000 to keep quiet about an alleged affair with Trump.Earlier this week, Clifford, who performs under the name Stormy Daniels, sued the President in Los Angeles Superior Court seeking to void the agreement, which she attached to her complaint.In a section dealing with "prior disclosures" of "confidential information," the agreement cites four people with whom Clifford had already shared such information.One of them was Angel Ryan.Online records reviewed by CNN show that Ryan obtained a trademark registration for the name Jessica Drake.Gloria Allred, Ryan's attorney, confirmed the link for CNN."Jessica Drake is still my client. She is Angel Ryan and the one whose name is in the settlement agreement," Allred told CNN. She said her client was never contacted about Clifford's settlement agreement.Allred would not comment on Ryan's relationship with Clifford, or the timing of her 2016 disclosure being so close to the drafting of Clifford's agreement.Both Clifford and Ryan worked for Wicked Entertainment and both said they attended a 2006 golf outing in Lake Tahoe, also attended by Trump.Clifford said in this week's court filing that she began "an intimate relationship" with Trump that summer, which continued into 2007.At the press conference in October 2016, Ryan, joined by Allred, said she was subjected to unwanted sexual advances by Trump at the golf tournament. She said he kissed her without asking and offered to pay her for sex.Trump campaign officials denied the allegations and said the candidate did not know his accuser.Six days later, Drake's real name appeared in the agreement related to Clifford.Cohen has publicly acknowledged using his own money to facilitate the payment to Clifford in the weeks before the presidential election. He said Trump had no knowledge that he was planning do so or had done so. He said Trump "vehemently denies" Clifford's allegations.The agreement specified three other people with whom Clifford had shared "confidential information." They are an ex-husband, a business manager, and a photographer.All three either declined comment or could not be reached. 3121

WEST PALM BEACH, Fla. — There were plenty of Palm Beach County residents opposed to a mask mandate. Now some of them are suing to stop it.A lawsuit filed Tuesday in Palm Beach County court seeks injunctive relief to overturn the county's order.Attorneys representing Palm Beach County residents Rachel Eade, Carl Holme, Josie Machovic and Robert Spreitzer claim the new order requiring that masks be worn in public places infringes upon the constitutional rights of the plaintiffs.The 37-page lawsuit, filed by the Coconut Creek-based Florida Civil Rights Coalition, argues that the plaintiffs and other residents are having their "well-settled constitutionally protected freedoms" violated, including their "constitutional and human right to privacy and bodily autonomy."The lawsuit goes on to say that the county, having no authority to do so under Florida law, "has recklessly required countless American citizens and Florida residents," including the plaintiffs, "to submit to dangerous medical treatments with well-known risks and potential for serious injuries and death, including being forced to wear harmful medical devices like masks."Palm Beach County commissioners unanimously voted last week in favor of the mask mandate to help prevent the spread of the coronavirus amid a recent surge in cases throughout the county and state.The lawsuit takes aim at the "ridiculously vague" language of the order, which attorneys for the plaintiffs claim forces residents and visitors "to guess at the meanings and be subjected to punishment and criminal consequence."It also chastises the order's exemptions "because it arbitrarily and absurdly discriminates against anyone over the age of 2 years old, and countless citizens" who don't meet the "unlawful order's vague and ambiguous exceptions."The lawsuit berates county leaders for not clearly defining terms like "businesses or establishments" and "persons" as it is written in the order."Are non-citizens included?" attorneys wrote. "One is only left to guess, which is why the unlawful order is void for vagueness."Attorneys for the plaintiffs argue that a permanent injunction "will serve the public interest.""Millions of Palm Beach County residents and visitors are burdened by the over-reach of their local government in a fashion not before seen in the history of Florida," they wrote, adding that residents are "unduly burdened" by this violation of their rights. "The public has a strong interest in protecting their rights and ability to control their own bodies in the workplace and in public."Palm Beach County State Attorney Dave Aronberg said during a news conference Friday that commissioners do, in fact, have the constitutional authority to mandate masks."Obviously, those individuals who claim that they know the First Amendment have obviously never read the First Amendment," Aronberg said. "Because it is within the authority of the County Commission to put forward a mask ordinance. They have the authority under state law. They have the authority under the Constitution."The lawsuit seeks expedited consideration because the order is currently in effect. A written response by the county is required within 20 days of the filing.Several studies show that a mask or facial covering limits the wearer from spreading airborne droplets when speaking, sneezing or coughing. The coronavirus can live outside the body in these droplets for several hours and, in turn, infect other people — even before the person who spread the droplets has exhibited symptoms of COVID-19.Earlier this year, the Centers for Disease Control and Prevention (CDC) issued guidance that strongly recommended all Americans over the age of 2 wear masks in public, particularly in situations that would make social distancing impossible.This story was originally published by Peter Burke on WPTV in Palm Beach, Florida. 3872

When Sgt. Brian Maynard pulled over Laura and Jimmy Baker, he was preparing to deliver a ticket. Instead, the state trooper summoned an EMS team, which delivered the couple's baby girl on the side of North Carolina's US 64 highway.It all began Saturday night in suburban Raleigh when Laura Baker got in a minivan with her husband for a visit to the hospital to check on some contractions she'd been having. Then, 10 minutes into their drive, she suddenly went to labor."I said, 'I cannot control this, we're not going to make it there,'" Baker said.So when her husband spotted Maynard's patrol car, he did everything he could to get the officer's attention, speeding and flicking his lights."As soon as we pulled over, my water broke," Baker said. "And my husband jumped out with his arms up, saying, 'My wife's in labor and I really need help.'"All three knew they didn't have time to get to a hospital. Maynard called the EMS team in nearby Wendell but was prepared to do the job himself."I said, 'OK, well, we're going to do this right here, me and you,'" he told CNN affiliate WSOC.So Baker's husband and Maynard held the mother's hands and urged her to wait for the EMS team."My husband and the trooper were nervous, because they certainly weren't prepared," she said. And when the EMS team arrived, everyone realized they couldn't get Baker on a stretcher. So she delivered in the front seat of the van.It was this team -- as well as the trooper's assistance -- that Baker said she's most thankful for."Without them, I don't know how successful it would have been," she said. "It was maybe a five-minute experience, but a vital five-minute experience. [The EMS team] did everything to make sure it was sanitary and healthy."Baker was taking her baby, Halyn, home Monday and was planning on paying a visit to the EMS team that helped keep her infant daughter healthy throughout the delivery. She doesn't know much about the EMS crew, but she'll be looking for Charlie and Danny, who held her hands throughout the birth and walked her through every step."She was born outside in 40-degree weather, but she's a perfect, healthy little girl," she said. "They did everything perfect." 2198

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