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As we're all focused on the current rollout of the COVID-19 vaccine, a technology known as thin-film freezing is getting a lot of attention. It's groundbreaking and could change the way we administer drugs or use medicine in general.You've probably heard about the need to keep the COVID-19 vaccine cold. It has to be so cold, in fact, that the shipment and transport are challenging. Well, what if that vaccine could be turned into powder?“What we’ve most recently been working on is the elimination of cold chain by storing as a powder, a dry powder where the drug is much more stable than if it was stored as a liquid or as a frozen liquid,” said co-inventor Dr. Robert Williams.Williams said it would eliminate the need for extreme cold storage and transport. The technology isn't new. He got a research grant and came up with it about 15 years ago.Williams, who is also a pharmacy professor at the University of Texas in Austin, said they were working on the technology and its multiple uses when the pandemic hit. And all of a sudden, they got a lot of attention.“We have published over 70 papers on the technology and using it for different products- it’s quite a mature process," Williams said. "We developed it because with other vaccines, the majority of the vaccine cost is in wastage because of this cold chain issue, so we published several key papers where we showed our thin-film freezing technology would protect vaccines - and you wouldn’t need cold chain storage.”Glenn Mattes, President, and CEO of TFF Pharmaceuticals added that the powders can be converted to topical preparations and they are currently working with the US Army to take some of the preparations and would then administer them directly through the eye.TFF is launching thin-film freezing into development through the FDA process. “I use the term ubiquitous because it is and disruptive because it is,” Mattes said. He added that they've explored their technology in the cannabinoid realm. But, as for the COVID vaccine, they're aiming for a second-generation usage.“To truly eradicate the pandemic, you have to have a global response," Mattes said. "The companies we’ve been speaking to certainly recognize the broad utilization of the technology but the application to the developing world, rural area, remote areas, where you can take a powder and inhale it or take the powder and reconstitute it has tremendous potential."Experts say it is only just the beginning as they launch their technology into a new world. 2511
As we head into the final days of the campaign, the environment is a major issue that perhaps does not get as much attention as others. COVID-19, the economy, and health care all are polling more important for most voters. But for some, the environment remains top of mind. "The environment is like the basis of everything," Anna Rose Mohr-Almeida, an 18-year-old voter in Arizona, said. "If we keep relying on oil, we aren’t going to make a clean transition," Mohr-Almeida said. Other voters are watching environmental policy more closely. Not because they want more reform, but because they worry about regulations that are too drastic. "We like clean air, we like clean water," Alan Olson with the Montana Petroleum Association said. "We have got a tremendous economy in the United States, primarily due to cheap fuel," Olson said. "Environmental regulations have to be realistic," Olson added. BIDEN VS TRUMPOn nearly every policy, the two presidential candidates differ, but it is especially apparent when it comes to the environment. During his administration, President Donald Trump has reversed nearly 100 environmental regulations. Trump removed the United States from the Paris Agreement, which is meant to stop rising temperatures by cutting emissions. The president is however committed to planting trees and did sign the Great American Outdoors Act, which Democrats and Republicans both believe will help protect federal lands for generations. Joe Biden, meanwhile, would immediately have the United States rejoin the Paris Agreement. Biden is committed to spending trillions to hire millions to create a "green economy."Biden wants net-zero emissions by 2050. While Biden has called the Green New Deal a framework, he has said he would not ban fracking. 1777

At a rally in Pittsburgh on Tuesday, President Donald Trump gloated about reporters who were injured and shoved to the ground while covering protests and riots earlier this summer.While sharing anecdotes about the unrest in Minneapolis following the death of George Floyd, Trump referred to an "idiot reporter from CNN with the shaved head" who "got hit on the knee with a canister of tear gas."Trump was likely referring to MSNBC anchor Ali Velshi, who was hit with a rubber bullet fired by the National Guard while covering the protests in Minneapolis.Later referred to an unidentified reporter who was thrown aside "like a bag of popcorn" as police attempted to clear out protesters.Both accounts garnered laughter and applause from the large crowd in attendance."When you see it, it's actually a beautiful sight. It's a beautiful sight," Trump said, referring to police clearing out protesters.It was the second time in less than a week that Trump has mocked Velshi's injury. On Friday, at a rally in Minnesota Trump called out Velshi by name, saying that his injury was "a beautiful thing" and the result of "law and order." 1137
At the end of summer, Christina Curfman would typically be rushing to prepare her second-grade classroom. However, it's different this year.“I started a garden,” said Curfman. “I’ve never planted vegetables my entire life, but my mom always had a garden, and I love it.” Her newfound happiness is coming with just as much heartbreak. “I submitted my retirement papers,” said the teacher of 28 years. It was a tough decision, but with COVID-19 threatening the in-person relationships she loved so much while teaching, she was forced to reconsider going back to school. “I had a student ask me, ‘Is this coronavirus going to kill us all?’ and I was like, ‘Oh my goodness. I’m not doing this anymore.’” Curfman knew her body couldn’t take the risk. “I have an autoimmune disorder. It’s similar to Rheumatoid Arthritis, so I have trouble walking," she explained. "The medications that I take kind of lowers your immune system, too.” On top of that, a few years ago, she spent weeks in the hospital for a blood clot in her lung. “I was saying goodbye to friends and family. It looked pretty dire, it looked like I wasn’t going to make it, and I wasn’t willing to test that again,” recalled Curfman. 1207
AVON PARK -- A traffic stop in Avon Park, Florida, on Sunday led to what the Highlands County Sheriff's Office calls one of the largest drug seizures in recent memory in their county. Deputies confiscated enough fentanyl to kill nearly 40,000 people, as well as over a pound of heroin and nearly a pound of cocaine.Around 7:40 p.m., Deputy Seth Abeln saw a blue Ford Focus on North Central Avenue that had a tag light out. After Abeln stopped the vehicle, Deputy Ben Jones and K-9 Gentry were called to do a free air sniff of the vehicle. According to the sheriff's office, Gentry indicated there were drugs in the car.A search of the vehicle turned up:● 554 grams of heroin● 450 grams of cocaine● 99.6 grams of fentanyl● 975 oxycodone pills● 107 Xanax pills● 90 vape pens with liquid THCThe sheriff's office says a dose of 2-3 milligrams of fentanyl is enough to be deadly, meaning there was enough of the drug to kill 40,000 people using 2.5 milligrams as a fatal dose. To put that in perspective, that would be enough to kill nearly 40 percent of the people in Highlands County.The street value of the fentanyl is ,000. Add that to the ,000 of cocaine, ,000 of oxycodone and ,000 of heroin, and the total seizure is worth 0,000 on the street, not including the value of the vape pens.There was also a loaded handgun inside the car. deputies say. The driver, 40-year-old Ruben Ramirez-Rivera, was arrested and charged with:● trafficking cocaine● trafficking heroin● trafficking oxycodone● trafficking a controlled substance● possession of opium or a derivative (fentanyl) with intent to sell/deliver● possession of a Schedule III or IV drug with intent to sell/deliver● possession of heroin with intent to sell/deliver● possession of cocaine with intent to sell/deliver● felony possession of marijuana● possession of a weapon during commission of a first-degree felony● possession of drug equipmentRivera is being held without bond at the Highlands County Jail.“I’m very proud of the work done by the deputies involved in this arrest,” Sheriff Paul Blackman said. “To take this amount of drugs off the street is a huge accomplishment, and our county is safer because of it.”This article was written by Dan Trujillo for WFTS. 2249
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