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WASHINGTON, April 3 (Xinhua) -- In the largest study of its kind, researchers from a consortium led by the University of Pennsylvania School of Medicine, the University of Miami, and the Boston University School of Medicine, identified four new genes linked to Alzheimer's disease. The findings appeared Sunday in the current issue of Nature Genetics.Each gene individually adds to the risk of having this common form of dementia later in life. These new genes offer a portal into what causes Alzheimer's disease and is a major advance in the field.The study, conducted by the Alzheimer's Disease Genetics Consortium, reports genetic analysis of more than 11,000 people with Alzheimer's disease and a nearly equal number of elderly people who have no symptoms of dementia. Three other consortia contributed confirming data from additional people, bringing the total number of people analyzed to over 54,000. The consortium also contributed to the identification of a fifth gene reported by other groups of investigators from the United States, the United Kingdom, France, and other European countries.The study is the result of a large collaborative effort with investigators from 44 universities and research institutions in the United States, led by Gerard Schellenberg at University of Pennsylvania."This is the culmination of years of work on Alzheimer's disease by a large number of scientists, yet it is just the beginning in defining how genes influence memory and intellectual function as we age. We are all tremendously excited by our progress so far, but much remains to be done, both in understanding the genetics and in defining how these genes influence the disease process," Schellenberg said.Until recently, only four genes associated with late-onset Alzheimer's have been confirmed, with the gene for apolipoprotein E-e4, APOE-e4, having the largest effect on risk. The Nature Genetics studies add another four -- MS4A, CD2AP, CD33, and EPHA1 -- and contribute to identifying and confirming two other genes, BIN1 and ABCA7, thereby doubling the number of genes known to contribute Alzheimer's disease.

WASHINGTON, May 17 (Xinhua) -- The U.S. National Aeronautics and Space Administration (NASA) announced Tuesday that the international Aquarius/SAC-D observatory will be launched on June 9, to study interactions between ocean circulation, the water cycle and climate by measuring ocean surface salinity.Engineers at Vandenberg Air Force Base in California are performing final tests before mating the satellite to its Delta II rocket. The mission is a collaboration between NASA and Argentina' s space agency, with participation from Brazil, Canada, France and Italy.In addition to Aquarius, the primary instrument, the observatory carries seven other instruments that will collect environmental data for a wide range of applications, including studies of natural hazards, air quality, land processes and epidemiology.The mission will make NASA's first space observations of the concentration of dissolved salt at the ocean surface. Aquarius' observations will reveal how salinity variations influence ocean circulation, trace the path of freshwater around our planet, and help drive Earth's climate. The ocean surface constantly exchanges water and heat with Earth's atmosphere. Approximately 80 percent of the global water cycle that moves freshwater from the ocean to the atmosphere to the land and back to the ocean happens over the ocean.Salinity plays a key role in these exchanges. By tracking changes in ocean surface salinity, Aquarius will monitor variations in the water cycle caused by evaporation and precipitation over the ocean, river runoff, the freezing and melting of sea ice. Salinity also makes seawater denser, causing it to sink, where it becomes part of deep, interconnected ocean currents. This deep ocean "conveyor belt" moves water masses and heat from the tropics to the polar regions, helping to regulate Earth's climate."Salinity is the glue that bonds two major components of Earth' s complex climate system: ocean circulation and the global water cycle," said Aquarius Principal Investigator Gary Lagerloef of Earth & Space Research in Seattle in a statement. "Aquarius will map global variations in salinity in unprecedented detail, leading to new discoveries that will improve our ability to predict future climate."Aquarius will measure salinity by sensing microwave emissions from the water's surface with a radiometer instrument. These emissions can be used to indicate the saltiness of the surface water, after accounting for other environmental factors. Salinity levels in the open ocean vary by only about five parts per thousand, and small changes are important. Aquarius uses advanced technologies to detect changes in salinity as small as about two parts per 10,000, equivalent to a pinch (about one-eighth of a teaspoon) of salt in a gallon of water.Aquarius will map the entire open ocean every seven days for at least three years from 408 miles (657 kilometers) above Earth. Its measurements will produce monthly estimates of ocean surface salinity with a spatial resolution of 93 miles (150 kilometers). The data will reveal how salinity changes over time and from one part of the ocean to another.

SAN FRANCISCO, May 10 (Xinhua) -- Google on Tuesday launched its long-awaited cloud-based music service Music Beta without any label licenses it originally wanted.The search giant introduced the digital music locker service at its annual I/O developer conference in San Francisco. So far, only U.S. users can access the service by requesting an invitation from Google while priorities will be given to those with the Verizon version of the Motorola Xoom tablet and attendees of the I/O conference.Since Google failed to come to a license agreement with major music labels, Music Beta is essentially a massive cloud hard drive. Users cannot share their Music Beta by Google tunes or purchase new songs. It allows users to upload 20,000 songs into the cloud, compared with Amazon Cloud Drive's 2,000 songs and 5 GB limit for free accounts.Any web-connected devices with a browser or supporting Flash can stream music from the digital locker, but the service is only for Android-powered devices.Music Beta also gets Instant Mix, a similar intelligent feature to Apple's Genius playlist creator, which creates new playlists based on a single song by analyzing its characteristics.Before unveiling the service, Google told U.S. media Monday night that the current Music Beta is not the service Google had wanted to offer and it will continue to seek licenses with major music labels.

LOS ANGELES, May 29 (Xinhua) -- Nineteen percent of

HOUSTON, April 15 (Xinhua) -- A major contractor for the U.S. space shuttle on Friday announced plans to lay off about 50 percent of its employees this summer after NASA retires the orbiter fleet.The contractor, Houston-based United Space Alliance, said it will cut 2,600 to 2,800 jobs, including 1,850 to 1,950 employees in Florida, 750 to 800 employees in Texas, and 30 to 40 employees in Alabama, "due to the completion of tasks related to day-to-day operations of the Shuttle fleet."The cuts will be made in late July and early August after NASA completes the final flight of Endeavour, scheduled for April 29, and the flight of Atlantis on June 28."The accomplishments of this team are unmatched in human spaceflight," Virginia Barnes, the company's president, said in a news release. "It will be difficult to say goodbye to such tremendously talented and dedicated teammates, and we are committed to making this transition as smooth as possible for them."United Space Alliance has approximately 5,600 employees working at sites in Texas, Florida and Alabama, according to the the news release.

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