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WASHINGTON, July 20 (Xinhua) -- The loss of a protein that coats sperm may explain a significant proportion of infertility in men worldwide, according to a study by an international team of researchers led by University of California Davis.A paper describing the work was published Wednesday in the journal Science Translational Medicine. The research could open up new ways to screen and treat couples for infertility.The gene DEFB126 encodes a protein called Beta Defensin 126, which coats the surface of sperm and helps it penetrate cervical mucus in the female. A survey of samples from the U.S., Britain and China showed that as many as a quarter of men worldwide carry two copies of the defective gene.In the new study, researchers found that men with a muted DEFB126 lack Beta Defensin 126, making it much more difficult for sperm to swim through the mucus and eventually join with an egg.Examining 500 newly married Chinese couples, researchers found that the lack of Beta Defensin 126 in men with the DEFB126 mutation lowered fertility (even among men that did not display other deficiencies usually associated with infertility, like inadequate semen volume and low sperm motility). Wives of men with the Beta Defensin 126 variant were significantly less likely to become pregnant than were other couples, and 30 percent less likely to have a birth.This genetic variation in DEFB126 likely accounts for many unexplained cases of infertility, researchers say. They hope next to work with a major infertility program in the U.S. to further explore the role of the mutation.
VIENNA, Sept. 9 (Xinhua) -- The three-day Traditional Chinese Medicine (TCM) exhibition opened Friday in the Flower Garden Hirschstetten in Vienna, with the aim to introduce traditional Chinese medicine to the Austrians and to arouse their interest in the culture of Chinese medicine.Holding for the second time, the exhibition this year have attracted more visitors to take part in the health talks on traditional Chinese medicine, read or buy books around the theme of traditional Chinese medicine. Some visitors enthusiastically tried Chinese diet therapy prepared by the organizers.In recent years, traditional Chinese medicine has been increasingly recognized and accepted in Austria. It has already not only entered into the classroom but also into the hospital and clinic.Some private health insurance companies in Austria have started to include the treatment by traditional Chinese medicine into their insuring categories. Chinese patent drugs are already available in many pharmacies in Austria.But in general, traditional Chinese medicine still faces many limits in Austria, which hasn't been involved into the public health insurance system. Some Austrians still have doubts of Chinese medicine, in particular the medicinal herb drugs. All these have restricted the development of traditional Chinese medicine here.Currently, major clinics of traditional Chinese medicine carry out only acupuncture and moxibustion, massage and other health-care physical therapy.Richard Schmerker, a doctor of traditional Chinese medicine in Austria, told reporters that the development of traditional Chinese medicine here still faces many challenges and the biggest one is the shortage of effective propaganda and popularization.But he expressed his full confidence about the future of traditional Chinese medicine in Austria. He said, the uniqueness of finding the root cause of diseases and laying the axe to the root will make it be accepted by more and more Austrians.
WASHINGTON, Aug. 4 (Xinhua) -- Researchers have found a way to turn mouse embryonic stem cells into sperm and this finding opens up new avenues for infertility research and treatment, according to a study published Thursday in the online edition of journal Cell,A Kyoto University team coaxed mouse embryonic stem cells into sperm precursors, called primordial germ cells (PGCs), and shown that these cells can give rise to healthy sperm. The researchers say that such in vitro reconstitution of germ cell development represents one of the most fundamental challenges in biology.When transplanted into mice that were unable to produce sperm normally, the stem cell derived PGCs produced normal-looking sperm, which were then used to successfully fertilize eggs. These fertilized eggs, when transplanted into a recipient mother, produced healthy offspring that grew into fertile male and female adult mice. The same procedure could produce fertile offspring from induced pluripotent stem cells that are often derived from adult skin cells."Continued investigations aimed at in vitro reconstitution of germ cell development, including the induction of female primordial germ cell-like cells and their descendants, will be crucial for a more comprehensive understanding of germ cell biology in general, as well as for the advancement of reproductive technology and medicine," the researchers wrote.
Robots perform a dance in a competition in Mudanjiang, northeast China's Heilongjiang Province, July 24, 2011. A nationwide robot competition was kicked off in the city on Sunday, with participants from 50 colleges and universities
BEIJING, Sept. 2 (Xinhuanet) -- Insomnia costs average U.S. worker 11.3 days, or 2,280 dollars, in lost productivity each year, according to a new study published in journal Sleep.The total cost to the nation is 63.2 billion dollars annually, the study said.Researchers analyzed information about sleep habits and work performance from 7,428 workers taking part in Harvard Medical School's American Insomnia Study survey in 2008-09.As a result, 23.2 percent of the participants suffered insomnia, characterized by a hard time falling or staying asleep.Moreover, insomnia rates were 19.9 percent for those with less than a high school education and 21.5 percent for college graduates."We were shocked by the enormous impact insomnia has on the average person's life," said Ronald C. Kessler, a lead author and a psychiatric epidemiologist at Harvard Medical School."It's an underappreciated problem. Americans are not missing work because of insomnia. They are still going to their jobs but accomplishing less because they're tired," Kessler noted.Employers usually ignore the consequences of insomnia because it's not considered an illness resulting in workers' absenteeism.But the high cost of lost sleep identified in this study indicates that employers need to take it more seriously.