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SAN FRANCISCO, Sept. 13 (Xinhua) -- Researchers in San Francisco, U.S. have found in a latest study that bisphenol A (BPA) and methylparaben, two chemicals commonly used in consumer products, can interfere with the breast cancer drugs, local media reported on Tuesday.In the study, doctors from California Pacific Medical Center in San Francisco found that healthy breast cells from high-risk patients started to find ways to bypass breast cancer drugs after they were exposed to BPA and methylparaben in the lab.The cells exposed to the two chemicals kept growing and didn't die after they were introduced with Tamoxifen, a current standard drug therapy for female breast cancer and most common used treatment for male breast cancer, Dr. William Goodson, lead author of the study, told San Francisco Chronicle.Goodson said that BPA and methylparaben not only mimic estrogen 's ability to drive cancer, but appear to be even better than the natural hormone in bypassing the ability of drugs to treat it. The finds have been published online in the British medical journal Carcinogenesis.The research shows more evidence of safety issues of BPA, a chemical primarily used to make plastic baby bottles, food containers, household electronics and etc, as well as the less known methylparaben, a chemical preservative used in cosmetics and other personal care products.The researchers noted that the breast cancer rates have been growing by about the same amount in men as in women over the past three decades. Scientists have been looking at environmental causes for the disease and wondering where the hormones are coming from.Goodson said BPA and methylparaben are used so widely and even found in household dust, noting that it is still unknown whether the effects of exposure to the chemicals are reversible.Since 2008, several governments issued reports questioning the negative health effects of BPA, especially raising concerns regarding exposure of fetuses, infants and children. BPA use has been banned in baby bottles in a lot of countries and regions.As for methylparaben, the U.S. Food and Drug Administration said on its website that "at the present time there is no reason for consumers to be concerned about the uses of cosmetics containing parabens (including methylparaben)."
SHENZHEN, June 18 (Xinhua) -- China established its first national gene bank on Friday in south China's city of Shenzhen with the support of the Beijing Genomics Institute (BGI), officials said.With the establishment of the National Gene Bank in Shenzhen, China will be able to better protect, research and utilize its precious genetic resources, boosting the genetics industry and safeguarding the country's genetic information, said Qi Chengyuan, head of the high-tech industry department of the National Development and Reform Committee (NDRC).The gene bank, which was approved by the NDRC in January, is based on data and facilities belonging to the BGI, but will grow with the help of extensive cooperation with other biological organizations both home and abroad, Qi said.The national gene bank "aims to lead the development of international bioindustry as one of the world's largest gene banks," said Yang Huanming, the BGI's president.The BGI, the world's largest genome-mapping institute, has more than 1,000 biological analysis devices working with top-of-the-line genome-sequencing machines.Analysts say the BGI differs from conventional labs, as it can handle data in vast quantities and industrialize its research. Some believe lower wages in China have also contributed to the BGI's competitiveness.Yang Bicheng, the BGI's spokesman, said the payment and welfare packages BGI offers are competitive in China's bioindustry."A researcher with about two years of experience earns around 100,000 yuan (15,440 U.S. dollars) a year. More outstanding researchers can get more, but the gap is not too great," Yang said.Yang said greater motivation comes from better prospects for academic achievements."Our young researchers can work with the world's leading scientists, participate in global science projects and be pioneers in new fields of research. Only BGI offers these kinds of opportunities in China," Yang said.The BGI has published 18 research papers in Science Magazine and the Nature Journal since 2007. The facility has become an international center for genome research and industrialization, with advanced technology and top talent, said Ji Xiaoming, head of the international cooperation department of the Ministry of Science and Technology.China is working to make its genetic research industry into one of the country's pillar industries.A plan approved by the State Council, or China's cabinet, in October 2010 said China will boost the industry by encouraging innovation, promoting industrial application of biological research, fostering market demand and deepening international cooperation.

WASHINGTON, June 7 (Xinhua) -- Advanced hepatitis C patients with chronic liver disease may benefit from drinking coffee during treatment, according to a new study published Tuesday in Gastroenterology, the official journal of the American Gastroenterological Association Institute.The study shows that patients who received peginterferon plus ribavirin treatment and who drank three or more cups of coffee per day were two times more likely to respond to treatment than non- drinkers.Among non-drinkers, 46 percent had an early virologic response; 26 percent had no detectable serum hepatitis C virus (HCV) ribonucleic acid at week 20; 22 percent had no detectable serum at week 48; and 11 percent had a sustained virologic response. In contrast, the corresponding proportions for those who drank three or more cups of coffee per day were 73 percent, 52 percent, 49 percent and 26 percent, respectively."Coffee intake has been associated with a lower level of liver enzymes, reduced progression of chronic liver disease and reduced incidence of liver cancer," said Neal Freedman, of the National Cancer Institute and lead author of this study. "Although we observed an independent association between coffee intake and virologic response to treatment, this association needs replication in other studies."Approximately 70 to 80 percent of individuals exposed to HCV become chronically infected. Worldwide, these individuals are estimated to number between 130 and 170 million. Higher coffee consumption has been associated with slower progression of pre- existing liver disease and lower risk of liver cancer. However, the relationship with response to anti-HCV treatment had not been previously evaluated.
BEIJING, July 20 (Xinhuanet) -- Some U.S. soldiers returning from the Middle East have acquired constrictive bronchiolitis, a kind of lung damage virtually unknown in young adults, according to U.S. News & World Report."Respiratory disorders are emerging as a major consequence of service in southwest Asia," said study author Dr. Matthew S. King, an assistant professor of pulmonary and critical care at Meharry Medical College in Nashville, Tenn."In addition to our study, there have been studies showing increases in asthma, obstructive lung disease, allergic rhinitis and a general increase in reports of respiratory symptoms," he added. "Most of the patients say they can’t seem to catch their breath when exerting themselves."On the other hand, Anthony Szema, a physician and engineer at Stony Brook University in New York, has examined a soldier and found tiny complexes of titanium and iron in the man’s lungs, where metals can cause severe damage.Mined separately, the two metals could have gotten together only through a manufacturing process, Szema reported. While the metals’ origin is unclear, he presents a new case study, suspecting garbage-burning pits or exploding devices sent them airborne.While the cases in the study represent only a few dozen people of the hundreds of thousands serving in the Middle East, there is no estimate of how many more might have bronchiolitis.it is recommended that soldiers exercise caution in the field until more is known. Soldiers are now told to wear a mask when burning garbage.
WASHINGTON, Sept. 13 (Xinhua) -- The U.S. Department of Agriculture (USDA) announced Tuesday it will begin testing next year for six more kinds of E.coli bacteria in raw ground beef and tenderized steaks in order to protect the safety of the American food supply.The U.S. currently tests for one strain of E.coli O157:H7 in beef. According to the USDA, from March 5 next year, if the E. coli serogroups O26, O103, O45, O111, O121 and O145 are found in raw ground beef or its precursors, those products will be prohibited from entering commerce.Like E.coli O157:H7, these serogroups can cause severe illness and even death, and young children and the elderly are at highest risk."The Obama Administration is committed to protecting our food supply and preventing illnesses before they happen," said Agriculture Secretary Tom Vilsack in a statement. "Today's announcement does exactly that by targeting and eliminating contaminated products from the market.""Too often, we are caught reacting to a problem instead of preventing it. This new policy will help stop problems before they start," he said.About one in six Americans becomes sick from a food borne illnesses each year, an epidemic that kills about 3,000 annually and hospitalizes 128,000, according to the U.S. Centers for Disease Control and Prevention.
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