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LONDON (AP) — AstraZeneca and Oxford University have acknowledged a manufacturing error that is raising questions about preliminary results of their COVID-19 vaccine.A statement Wednesday describing the error came days after the company and the university described the shots as “highly effective” and made no mention of why some participants didn’t receive as much vaccine as expected.In a surprise, the group of volunteers that got half a dose in the first of their two shots seemed to be better protected than the volunteers who got full doses. The low-dose group was smaller and younger, however, which could have skewed the results, experts say.In a statement obtained by CNN, Oxford elaborated further, saying that a “difference in the manufacturing process” had led to the error.The university said that it discussed the problem with regulators, agreed to complete the late stage trial with two groups, and the problem has since been corrected. 959

LOS ANGELES, Calif. – Actor Elliot Page came out as transgender Tuesday.The Oscar-nominated performer, known for his roles in projects like “Juno” and “The Umbrella Academy,” said his pronouns are he/they.“I want to share with you that I am trans, my pronouns are he/they and my name is Elliot,” he said in a statement posted on Twitter.In the statement, Page said he feels overwhelming gratitude for the people who have supported him along his journey to self-acceptance.“I can’t begin to express how remarkable it feels to finally love who I am enough to pursue my authentic self,” wrote page. “I’ve been endlessly inspired by so many in the trans community.”Page wrote that he hopes to offer whatever support he can and strive for a more loving and equal society. He also asked for patience as he transitions.“The truth is, despite feeling profoundly happy right now and knowing how much privilege I carry, I am also scared. I’m scared of the invasiveness, the hate, the 'jokes' and of violence,” Page wrote.In his statement, Page addressed the staggering statistics surrounding the discrimination and violence towards trans people.“In 2020 alone, it has been reported that at least 40 transgender people have been murdered, the majority of which were Black and Latinx trans women,” he wrote.He went on to accuse political leaders and others who “spew hostility” towards the trans community of having blood on their hands.“To all trans people who deal with harassment, self-loathing, abuse and the threat of violence every day: I see you, I love you and I will do everything I can to change this world for the better,” Page said at the end of the statement.pic.twitter.com/kwti60bZLw— Elliot Page (@TheElliotPage) December 1, 2020 Editor's note: A previous version of this article referenced Elliot Page’s former name, following GLAAD’s guidelines, but the name has since been removed to better respect the trans community, per style guidelines from the Trans Journalists Association. 1995

LOS ANGELES (CNS) - A member of a downtown Los Angeles street gang caught with thousands of dollars worth of methamphetamine packaged to resemble 14 foil-wrapped burritos was sentenced Monday to 15 years behind bars for federal drug and gun crimes.Ricardo ``Flaco'' Renteria, 48, of Colton, was also ordered to serve five years of supervised release following prison and pay a mandatory special assessment of 0.``He has a very long criminal history,'' Chief U.S. District Judge Virginia A. Phillips said from the bench. ``This was a large amount of methamphetamine -- and the way it was packaged, it was clearly for sale.''According to evidence presented at trial, Los Angeles police officers pulled Renteria over on Feb. 3, 2018, in the Angelino Heights neighborhood of Los Angeles after they witnessed him erratically and evasively driving a white Chevrolet Tahoe.Renteria consented to a search of the SUV and law enforcement found a black garbage bag on the floor behind the driver's seat. Inside the bag were 14 foil-wrapped, burrito-shaped packages containing 13.7 pounds of methamphetamine with a street value ranging from ,000 to ,000.A subsequent search revealed a fully loaded Smith & Wesson .38 Special handgun and more than 0 in cash, evidence showed. Renteria was arrested at the scene and indicted by a federal grand jury in March 2018.After a one-day bench trial in March, Phillips found him guilty of three felonies: possession with intent to distribute methamphetamine, being a felon in possession of a firearm, and possession of a firearm in furtherance of a drug trafficking crime.At his sentencing hearing, Renteria asked the judge to ``take into consideration (that) I have a family waiting for me -- and I apologize for the situation I find myself in.''But Phillips said that a significant prison sentence was necessary ``to protect the public from further crimes of the defendant.'' She also recommended that Renteria undergo a mental and physical health examination while behind bars. 2031

LORAIN, Ohio - A family has filed a lawsuit against the Lorain County School District in Lorain, Ohio after their daughter was wrongly accused of bringing drug-laced candy to lunch in September and suspended.Shannon Ciotti and her daughter have filed a suit naming the district, the Lorain City Board of Education, every board member, the district CEO and the Lorain Police Department.Ciotti said her daughter was suspended immediately from Southview Middle School after being accused of bringing tainted candy, before any test was ever conducted on the candy. The director of out of school suspension cited Ciotti’s daughter with a level three violation – possession of marijuana edibles.The lawsuit states a 10-day suspension turned into 21 because the police department took so long to test the candy. The box of Milk Duds was not properly tagged as evidence and sat on a shelf in the police department, “untested and abandoned,” the court filing states. It was only after the crime lab found out from Ciotti that the evidence was improperly tagged that they tested the candy.The family also contacted the Hershey Company, who tested the batch of Milk Duds for illegal substances, the suit states.Hershey came to the same conclusion that Lorain police eventually did: the candy contained no illegal substances.According to the lawsuit, the teen has been harassed and ridiculed since returning to Southview Middle School. Fellow students have called her names like “pothead,” and a teacher allegedly mocked the girl, saying, “I hope you’re not planning on exchanging candy. We’ve been down that road before.”The lawsuit seeks ,000 in compensatory damages and over ,000,000 in punitive damages for negligence, gross negligence and defamation on behalf of the school and police. 1796

LOS ANGELES (KGTV) -- Porto’s Bakery and Cafe founder Rosa Porto died Friday at the age of 89, the business confirmed in a Facebook post. The founder of the popular Southern California bakery passed away peacefully Friday with her husband by her side, the company said.According to KABC, Rosa launched Porto’s Bakery after escaping to the United States from Cuba. RELATED STORIESBakery creates Los Angeles' largest-ever 'Rosca de Reyes'Porto's Bakery in Los Angeles to ship pastries you can bake at homeThe business started out of Rosa’s kitchen and later made the move to Echo Park. Read the full statement from Porto’s below: 636