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SAN DIEGO (KGTV) - Many of us have faced battles in 2020 we never imagined we would meet. But few have had to endure the hurdles of Bryce Olson."I started to come to terms with my own mortality," said Olson in November of 2018. "I didn't even think I would see my kid get out of elementary school, and I started losing hope."We have been following Bryce Olson's story for over two years. We profiled the Oregon man because he had been traveling to San Diego for research and precision therapies for his Stage 4 Metastatic Prostate Cancer. And then the pandemic hit."It makes me feel that I'm a sitting duck," added Olson back in March.Our Michael Chen revisited Olson nine months ago at the beginning of the pandemic. COVID-19 cases were on the rise, and Olson had to weigh the risk of traveling with a weak immune system or slowly dying without his treatment."It was kind of this Sophie's Choice issue of, you know I might die of cancer in the long term, but gosh COVID could kill me in the short term," said Olson just last week.But instead, something remarkable happened when Olson's story started spreading."And then your piece aired, and an amazing individual, super generous, kind individual saw that, and he had access to private transportation," said Olson with a smile.That good Samaritan was co-founder and former CEO of Sprouts, Shon Boney. He provided a private plane so Bryce could fly into San Diego for his treatments until he was healthy enough to fly commercially."He got me out of my shell," added Olson. "He got me back into San Diego, comfortable going into the hospital with my N95 mask and he increased my confidence in being able to do this."The timing was perfect. Olson couldn't spare another missed treatment. The cancer had spread to his spine, and within weeks he would have been unable to walk. But that was just the beginning of his renewed hope. WIRED then picked up Olson's story, which has led to even more attention, a consortium of his case study and the potential for revolutionary experimental therapies through Research to the People benefiting not just Olson but millions of other cancer patients."What's happened post WIRED is I've got all these researchers, scientists, and medical professionals that want to help me take this amazing set of data," added Olson. "And they'll use that and compare it with data that they have, and then make inferences if you will or hypothesize what I should do next."All of this has left Olson grateful in this Season of Hope. Grateful for Ashley, his girlfriend here in San Diego, and newfound love. Grateful for his daughter, who will get more time with her father than was first expected. And, of course, the medical community."I'm grateful for the amazing medical professionals, and scientists, and researchers that have helped me and get me as far as I am today," says Olson. "And who I know will help me live decades into the future. I'm grateful for that." 2945

SAN DIEGO (KGTV) — In the race for a coronavirus vaccine, scientists often say we need more than one winner.That’s in part because different vaccines use different strategies to provoke the immune system, and each strategy has different strengths.Take the inactivated virus vaccine, an approach currently used in the vaccine against the poliovirus. In this approach, scientists take a live virus, kill it with chemicals or heat, and then introduce that viral corpse into a person.There are three groups in the final phase of human trials using inactivated coronavirus, primarily in China, according to a tracker from the Milken Institute.“The immune system can tell the difference between something that's a real threat and something that's not a threat, and so if you get injected with a dead virus your immune system has the tendency to not pay a lot of attention to that,” said Dr. Shane Crotty of the La Jolla Institute for Immunology.The downside of the inactivated virus approach is that it only elicits two out of the three of the parts of the immune system, Dr. Crotty said. It’s capable of producing antibodies and helper T-cells, but not killer T-cells.The modern take on the inactivated virus approach is called a viral vector vaccine.In this strategy, scientists combine elements of the coronavirus with a common cold virus called an adenovirus that won’t make you sick. Since the virus is alive, it can elicit all three kinds of immune responses, Dr. Crotty said.“There are no licensed vaccines right now that use that strategy, but there are all kinds of vaccine trials that have been done around the world with those types [of vaccines] showing that they're straightforward to manufacture. They're very safe,” he said.The University of Oxford is testing a viral vector vaccine for COVID-19 in a Phase 3 clinical trial.Then there are subunit vaccines. These include just a section -- or subunit -- of the virus’ protein.UC San Diego is working on a coronavirus candidate vaccine using this approach.There are subunit vaccines currently on the market for tetanus and other viruses.“Working with proteins is more challenging, just from a laboratory and manufacturing perspective,” Dr. Crotty said.Enter the next phase of vaccine development. Instead of using the virus itself or fragments of it, Inovio Pharmaceuticals is working on a vaccine strategy using just the virus’ genetic information.DNA-based vaccines simply introduce a genetically engineered blueprint of the virus into a person, and the cells do the rest.“Some people get confused about this. They think it’s a genetic vaccine that changes their DNA and becomes part of them, and that’s definitely not the case.” Dr. Crotty said. “They don’t become part of you. Your body chews them up.”Researchers have been working on DNA-based vaccines for about 20 years, Crotty said, but none are currently licensed for use.San Diego-based Arcturus Therapeutics is using an RNA-based approach, along with other companies like Pfizer and Moderna that have entered Phase 3 trials.Messenger RNA reads the DNA instructions and helps translate them into proteins.Dr. Crotty said the DNA and RNA approaches have similar drawbacks and benefits: they’ve never been approved for us, but both can be developed rapidly because they don’t require access to the physical virus.Around the world, there are more than 200 coronavirus vaccines currently in development, according to the Milken Institute. 3459

SAN DIEGO (KGTV) — Local law enforcement made the holidays a little brighter for hundreds of deserving kids. The 26th annual "Shop with a Cop" event brought 300 kids out to go on a shopping spree with local officers, from San Diego Police to California Highway Patrol to San Diego County Sheriff's deputies.The shopping spree was just the tip of the iceberg for kids Saturday morning. Their day started at SeaWorld San Diego, where they had breakfast with officers and enjoyed a Christmas-themed dolphin show. RELATED:East County family's Santa treehouse helps families in needMAP: San Diego's best holiday light displays to see this yearMore than 300 officers then escorted the kids to the Sports Arena Target location via police motorcade, where the holiday fun began.Each child was given 0 for their own shopping spree, which they spent of everything from board games to action figures to even gifts back to officers.The goal is to not only provide kids with a happier holiday season, but to encourage positive interaction with law enforcement. 1059

SAN DIEGO (KGTV) — Local health officials said Thursday a new case of vaping-related lung injury has been reported, as county leaders prepare to consider new vaping regulations.So far in San Diego, there have been 43 confirmed cases of vaping-associated lung injury with three cases under investigation. There haven't been any local deaths, but all patients have had to be hospitalized. Those affected range in age from 17 to 70 years old, according to the county.The CDC has said that vitamin E acetate and tetrahydrocannabinol (THC) are closely linked with e-cigarette, or vaping, associated lung injury. CDC recommends people avoid using THC-containing e-cigarettes or vaping products.RELATED: San Diego woman hospitalized with vaping illness warns others“Vaping-related lung injuries continue to be reported in the region and that’s concerning,” said Wilma Wooten, county public health officer.As of Jan. 7, the CDC has reported 2,602 hospitalizations or deaths from sudden and severe lung injuries associated with vaping.The San Diego County Board of Supervisors is set to discuss several potential local actions on regulating e-cigarette devices during a Jan. 14 meeting. Those ordinances include a ban on flavored tobacco sale and distribution, device moratorium, and restricting e-cigarette smoking to outdoor areas at restaurant. The ordinances would apply to unincorporated parts of the county.“As stewards of public health; we have a responsibility to raise awareness and act in the best interest of the public to protect them,” said Supervisor Fletcher. “Right now we simply do not know enough about the chemicals being consumed and their impacts. We are acting in a similar fashion to other jurisdictions in California, we are acting with an abundance of caution.” A second meeting on the ordinances will be held on Jan. 28. If the ordinances pass, they will go into effect July 1. 1902

SAN DIEGO (KGTV) -- Hundreds showed up for a prayer vigil Wednesday night, organized by the Broadway Heights Community Council. The Prayer Vigil for Love, Peace and Justice was outdoors on Martin Luther King Jr. Way. A dozen faith leaders participated, each taking a moment to speak to the crowd and then share prayer with the crowd. Organizers say they put this together in response to the racial injustice around the country, mentioning the death of George Floyd and the arrest of Amaurie Johnson at the trolley station in La Mesa. The vigil was peaceful and organizers say that was the goal. Families that attended the event and faith leaders say they are hopeful that coming together will lead to meaningful change and healing. 740