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For the first time in more than a decade, a new treatment to improve brain function for Alzheimer’s disease has been submitted to the Food and Drug Administration (FDA) for review.This was after the drug trial was stopped and then a second look revealed some promising results.The Waterhouse family has seen the impact of Alzheimer’s firsthand.Gina and Steve Waterhouse have been a team most of their lives. They’ve been married for 43 years and ran several businesses together. Then in 2016, things started to change. Gina didn’t notice anything but employees at the family's businesses did.“I wasn't remembering some of the stuff I was supposed to be doing,” said Gina.Gina was diagnosed with early Alzheimer's disease that year.“They said, 'well you can come back in a year. We will check and see how you're doing, or we have a drug trial if you're interested,'” said Gina.Gina and Steve spent the next two and a half years at the Mayo Clinic, where Gina eventually got high doses of the drug aducanumab.Steve started to notice Gina was remembering more things and reported it back to doctors.“He just smiled and said, 'let me tell you what we're seeing. We're seeing cognitive improvement. And it’s the first time in my career.' These doctors said in their career that we've ever seen it,” said Steve.“He was so excited,” said Gina.Then in 2019, the drug trial suddenly ended. Gina says she felt like she’s gone downhill a little since it did.Rebecca Edelmeyer, PhD, with the Alzheimer’s Association, says the trial stopped early based on a futility analysis.“It was a statistical analysis that was done by the Biogen team, predicting that the trial would not actually be successful,” said Edelmeyer.Edelmeyer says then upon a second look at the trial data, they found that those people on the highest dose of the drug were seeing improvement in their brain function. She called it a very important moment for the Alzheimer’s research community.Now, the government will determine whether or not the drug is safe and effective enough to use.Steve mentioned there were some possible side effects like bleeding of the brain, but Gina did not experience any.Meanwhile, Gina can no longer take the drug. She and Steve have decided to retire.“We just decided tomorrow has to come today and we're having a great time. We're loving life,” said Gina.You can learn more about aducanumab here. 2394
First lady Melania Trump underwent kidney surgery Monday at Walter Reed National Military Medical Center near Washington, DC, according to a statement from her office.Trump had been experiencing an issue with her kidney that her office described as benign, but requiring medical attention.Trump, who turned 48 last month, entered Walter Reed in nearby Bethesda, Maryland, on Monday morning and is expected to remain hospitalized for several days following the operation, according to the statement from her communications director, Stephanie Grisham.She is the first US first lady to undergo such a serious medical procedure while in the White House since Nancy Reagan had a mastectomy in October 1987. Rosalynn Carter underwent surgery to remove a benign lump from her breast in April 1977. Weeks after Betty Ford became first lady, she was diagnosed with breast cancer and underwent a mastectomy in September 1974.President Donald Trump remained in the White House during Melania Trump's surgery.On May 7, Trump, a relatively private first lady by comparison to her most recent predecessors, was once again front and center, this time to unveil her formal platform, Be Best. She kicked off the initiative with a Rose Garden speech lasting 11 minutes, the longest public speaking engagement during her 16-month tenure as first lady.Be Best is a three-pronged platform with a focus on opioid addiction and families, general physical and emotional well-being of children, and kindness and safety for kids using social media. The latter caused a firestorm of controversy because it encompasses cyberbullying, a tactic that Melania Trump's husband, the President, has often been accused of fueling.In March, the first lady addressed the criticism she has faced by taking up the issue during opening remarks to a meeting she convened at the White House for tech industry leaders from Google, Snap, Twitter, Facebook, Amazon and others."I am well-aware that people are skeptical of me discussing this topic," she said. "I have been criticized for my commitment to tackling this issue, and I know that will continue. But it will not stop me from doing what I know is right."Melania Trump has also appeared with her husband several times in recent weeks. He was seated in the front row during her Be Best speech, after which he made remarks praising her commitment to helping children, and he was again second to speak, after his wife, during the Military Mothers and Spouses Ceremony on Friday in the White House East Room."She's become a very, very popular first lady. I'm reading that ... They love Melania," the President said. A new CNN poll released May 7 had the first lady's favorable rating up 10 points since January to 57 percent. 2757
Former Trump campaign adviser Rick Gates is finalizing a plea deal with special counsel Robert Mueller's office, indicating he's poised to cooperate in the investigation, according to sources familiar with the case.Gates has already spoken to Mueller's team about his case and has been in plea negotiations for about a month. He's had what criminal lawyers call a "Queen for a Day" interview, in which a defendant answers any questions from the prosecutors' team, including about his own case and other potential criminal activity he witnessed.Gates' cooperation could be another building block for Mueller in a possible case against President Donald Trump or key members of his team. 698
For more than three decades, the Catholic Church has been rocked by sex abuse scandals spanning the globe.And for decades, the church has been accused of protecting itself rather than the victims of child sexual abuse.Here are some major scandals and revelations involving the Catholic Church and allegations of abuse. 326
FRESNO, Calif. -- A Fresno firefighter is mourning the loss of his wife after she died shortly after giving birth to twins.Nick Reeder says his wife Amanda gave birth to two healthy twins last Monday when things took a turn for the worst, according to ABC30.After meeting her newborn twins, Amanda passed out. Doctors say an aneurysm quickly took her life.Reeder says he wants to share his story to let people know it could happen to anyone, even healthy mothers, and to share his story about the woman he calls the love of his life.As of Monday afternoon, a GoFundMe set up to help support the family has surpassed its ,000 goal. 641