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WASHINGTON, March 22 (Xinhua) -- A long-term study by Greek researchers has shown the effectiveness of replacing bone marrow, purposely destroyed by chemotherapy, with autologous (self) stem cells in treating people with aggressive forms of multiple sclerosis (MS).The study was published on Tuesday in Neurology, the medical journal of the American Academy of Neurology.For the treatment, chemotherapy drugs are used to kill all of the patient's blood cells, including the immune cells that are believed to be attacking the body's own central nervous system. Bone marrow stem cells removed from the patient are purified and transplanted back into the body, which saves life by replacing the blood cells and also is proposed to "reboot" the immune system.A human embryonic stem cell line derived at Stanford University is seen in this handout photo released to Reuters by the California Institute for Regenerative Medicine, March 9, 2009The study followed 35 people for an average of 11 years after transplant. The study involved people with rapidly progressive MS who had tried a number of other treatments for MS with little or no effect. All were severely disabled by the disease, with an average score of six on a scale of disease activity that ranges from zero being a normal neurological examination to 10 meaning death due to MS.A score of six means able to walk with a cane or crutch; a seven is mainly in a wheelchair. All had worsened by at least one point on the scale in the year prior to the transplant.After the transplants, the probability of participants having no worsening of their disease for 15 years was 25 percent. The probability was higher -- 44 percent -- for those who had active brain lesions, which are a sign of disease activity, at the time of the transplant.For 16 people, symptoms improved by an average of one point on the scale after the transplant, and the improvements lasted for an average of two years. The participants also had a reduction in the number and size of lesions in their brains. Two people (six percent) died from complications related to the transplant at two months and 2-1/2 years post-transplant.Study author Vasilios Kimiskidis, of Aristotle University in Thessaloniki, Greece, noted that more research is needed on this treatment, including studies that compare people receiving the treatment to a control group that does not receive the treatment."Keeping that in mind, our feeling is that stem cell transplants may benefit people with rapidly progressive MS," he said. "This is not a therapy for the general population of people with MS but should be reserved for aggressive cases that are still in the inflammatory phase of the disease."

WASHINGTON, May 25 (Xinhua) -- Two U.S. astronauts conducted the third of four scheduled spacewalks for space shuttle Endeavour 's STS-134 mission on Wednesday morning, the U.S. National Aeronautics and Space Administration (NASA) announced.Endeavour's mission specialists Drew Feustel and Mike Fincke completed a six-hour-54-minute spacewalk at 8:37 a.m. EDT (1437 GMT). They completed all planned tasks, installing cables to increase redundancy for the power system on the Russian segment of the station, completing the external wireless antenna system work Feustel and Greg Chamitoff began during the first spacewalk, and installing a power and data grapple fixture to Zarya. The fixture will allow the station's robotic arm to "walk" to the Russian segment, extending its reach by using that grapple fixture as a base.It was the 247th spacewalk conducted by U.S. astronauts, and the 158th in support of space station assembly and maintenance, totaling 995 hours and 13 minutes. If everything goes as planned, the 1,000th hour of space station assembly and maintenance will be logged on Friday.Endeavour lifted off on May 16 from the Kennedy Space Center in Florida, to deliver to the International Space Station a 2-billion- dollar, multinational particle detector known as the Alpha Magnetic Spectrometer (AMS).AMS, a particle physics detector, is designed to search for various types of unusual matter by measuring cosmic rays. Its experiments are designed to help researchers study the formation of the universe and search for evidence of dark matter, strange matter and antimatter.NASA's 30-year-old shuttle program is ending due to high operating costs. The Obama administration wants to spur private companies to get into the space taxi business, freeing NASA to focus on deep space exploration and new technology development.There were initially five space shuttles in the fleet -- Challenger exploded shortly after liftoff in 1986 and Columbia disintegrated on its way back to Earth in 2003. Discovery retired earlier this year, while Endeavour is currently on its final mission. A last mission for Atlantis is scheduled for July, though funding for Atlantis remains in question.The sixth shuttle, Enterprise, did test flights in the atmosphere but was never flown into space. It is already on display at a museum outside Washington.When the U.S. space shuttle program officially ends later this year, the Russian space program's Soyuz capsule will be the only method for transporting astronauts to and from the station.

WASHINGTON, May 17 (Xinhua) -- A variation in a gene involved in regulating cholesterol in the bloodstream also appears to affect progesterone production in women, making it a likely culprit in a substantial number of cases of their infertility, a new study from Johns Hopkins University researchers suggests.The Hopkins group has also developed a simple blood test for this variation of the scavenger receptor class B type 1 gene ( SCARB1) but emphasized there is no approved therapy yet to address the problem in infertile women.Following up studies in female mice that first linked a deficiency in these receptors for HDL -- the so-called "good" or " healthy" cholesterol -- and infertility, researchers report finding the same link in studies of women with a history of infertility.The findings has been published on-line this week in the journal Human Reproduction.If the new study's findings hold up on further investigation, the John Hopkins team says they not only will offer clues into a genetic cause of some infertility, but could also lead to a treatment already shown to work in mice."Infertility is fairly common and a lot of the reasons for it are still unknown," warns endocrinologist Annabelle Rodriguez, an associate professor of medicine at the Johns Hopkins University School of Medicine and the lead author. "Right now, the benefit of this research is in knowing that there might be a genetic reason for why some women have difficulty getting pregnant. In the future, we hope this knowledge can be translated into a cure for this type of infertility."

MOSCOW, Jan. 21 (Xinhua) -- Russian and Chinese companies started construction of an iron ore dressing plant Friday in the Evreyskaya Autonomous Oblast to provide high-grade iron ore to the Asia Pacific region, including China.Yury Makarov, chief executive officer of IRC Ltd., told Xinhua the plant would reach its designed capacity in 2013 at 10 million tons of iron ore and 3.2 million tons of iron ore concentrates, which contain up to 65 percent iron.Makarov said that 20 percent of the iron ore concentrates, which are natural iron ore processed through crushing, grinding and dressing, would be used to meet demands of Russia's far east and the rest would go to the Asia-Pacific market. Currently, China imports large amounts of concentrates from Brazil, Australia and India."We are very open to interaction with various countries of the Asia-Pacific region, especially China. The volume of processed iron ore has been increasing every year. We will be happy to deliver iron ore to your companies as well as any other consumers who are willing to purchase our products," he said.The plant will draw its resources from the Kimkanskoye and Sutarskoye deposits and send its products through the Khabarovsk Krai and the Suifenhe port to China.The plant is only 7 km from the Trans-Siberian Railway. A railway bridge is being planned between Evreyskaya Oblast and Heilongjiang to further shorten the supply route.Total investment in the plant is 400 million U.S. dollars, with 340 million in loans from the ICBC (Industrial and Commercial Bank of China) in China. Interest under the facility will be charged at 2.8 percent above LIBOR per annum. The China National Electric Engineering Co, Ltd is tasked with the construction of the plant.Makarov said he was very optimistic about the future of the plant and the development of relations between the Russia's far east and China's northeastern region.IRC Ltd. is a metal unit of Russian gold miner Petropavlovsk PLC. It became the second Russian company to be listed on the HK stock exchange, when it started trading on Oct. 21.

SYDNEY, May 27 (Xinhua) -- A toddler and a policeman have become the latest victims of a rare and potentially deadly mosquito-borne disease in Western Australia (WA), local media reported on Friday.The two-year-old child contracted Murray Valley encephalitis (MVE) in the Kimberley of WA and is now in Royal Darwin Hospital in a stable condition, according to Australian Associated Press (AAP).The 29-year-old police officer, who was recently contracted the disease at an Aboriginal community of WA, has emerged from a coma in a Perth hospital but is still unable to communicate.It is not known if the victims from WA's far north will fully recover.In April 2011, a man who had been traveling in WA's northwest became the first person in the state to die from the disease in three years.A 19-year-old Canadian tourist also died after contracting MVE while traveling through the Northern Territory earlier in May.A WA Health Department spokeswoman said nine West Australians had contracted MVE so far in 2011. Several people remain very ill in hospital, she said.