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Bulked-up, mutant “mighty mice” held onto their muscle during a monthlong stay at the International Space Station, returning to Earth with ripped bodybuilder physiques, scientists reported Monday.The findings hold promise for preventing muscle and bone loss in astronauts on prolonged space trips like Mars missions, as well as people on Earth who are confined to bed or need wheelchairs.A research team led by Dr. Se-Jin Lee of the Jackson Laboratory in Connecticut sent 40 young female black mice to the space station in December, launching aboard a SpaceX rocket.In a paper published in the Proceedings of the National Academy of Sciences, Lee said the 24 regular untreated mice lost considerable muscle and bone mass in weightlessness as expected — up to 18%.But the eight genetically engineered “mighty mice” launched with double the muscle maintained their bulk. Their muscles appeared to be comparable to similar “mighty mice” that stayed behind at NASA’s Kennedy Space Center.In addition, eight normal mice that received “mighty mouse” treatment in space returned to Earth with dramatically bigger muscles. The treatment involves blocking a pair of proteins that typically limit muscle mass.A SpaceX capsule brought all 40 mice back in good condition, parachuting into the Pacific off the California coast in January. Some of the ordinary mice were injected with the “mighty mice” drug after returning and quickly built up more muscle than their untreated companions, Lee said.The scientists completed the experiment just as the coronavirus was hitting the U.S.“The only silver lining of COVID is that we had time to write it up very intensively” and submit the results for publication, said Dr. Emily Germain-Lee of Connecticut Children’s Medical Center, Lee’s wife who also took part in the study. Both are affiliated with the University of Connecticut.While encouraged by their findings, the couple said much more work needs to be done before testing the drug on people to build up muscle and bone, without serious side effects.“We’re years away. But that’s how everything is when you go from mouse to human studies,” Germain-Lee said.Lee said the experiment pointed out other molecules and signaling pathways worth investigating — “an embarrassment of riches ... so many things we’d like to pursue.” His next step: possibly sending more “mighty mice” to the space station for an even longer stay.Three NASA astronauts looked after the space mice, performing body scans and injections: Christina Koch and Jessica Meir, who performed the first all-female spacewalk last fall, and Andrew Morgan. They are listed as co-authors.___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. 2835

CANARSIE, Brooklyn — This past weekend has been excruciating for a Brooklyn woman who was the victim of a heartless robbery.Anaika Forbes' 13-year-old shih tzu pekingese was swiped from her parked car. The brazen theft happened Saturday at about 3:45 p.m. on Avenue N near Canarsie Road in Canarsie, where the vehicle was parked.Forbes, who lives in a basement apartment on Avenue N, was overwhelmed that day dealing with flooding in her unit due to afternoon showers.“I was just going back and forth to the car bringing my stuff out, it was raining and just so much was happening,” she told PIX11.Her dog, Taffy, was placed in the unlocked car during the shuffle.When Forbes stepped back into her home to grab a few more things, an unknown woman snatched Taffy, Forbes said.In surveillance footage obtained by Forbes taken from across the street, a woman is seen opening the passenger car door of Forbes' dark-colored car, grabbing the dog and nonchalantly walking away with her by the leash.“She’s not a barking dog. She’s super sweet; she would go with anyone,” a tearful Forbes said. “I just want her back.”Forbes, who canvassed the neighborhood all day and night on Saturday and for a good part of Sunday, has launched an online campaign to get Taffy back, even offering a 0 reward for her return.“Please return Taffy, no questions asked,” she said in a plea to the unidentified woman. “She is my everything, I’ve had her since she was 3 months old.” 1466

CALEXICO, Calif. (KGTV) — U.S. Customs and Border Protection officers seized more than million worth of narcotics in a single vehicle stop this week.CBP says officers stopped a 55-year-old driver at about 4 a.m. at the Calexico Port of Entry and referred the driver to a secondary inspection, where an x-ray imaging system identified anomalies in the vehicle.A search of the vehicle turned up 20 packages of fentanyl weighing 48 pounds, and 121 packages of methamphetamine weighing 517 pounds hidden in the floor, gas tank, seats, and spare tire.The driver was arrested and turned over to Homeland Security officials. 628

CARLSBAD, Calif. (KGTV) - A company in Carlsbad is doing its part to help the animals injured by wildfires in Australia.Oska Wellness has donated ten of its patented Oska Pulse devices to animal hospitals in New South Wales."I have a cat and a dog, my daughter has a snake, we're animal lovers," says Dr. Jeff Marksberry. "So anything you can do personally or as an organization, we're going to do."The device uses electromagnetic pulses to help realign the ionic charges within damaged cells. "All of your cells in your body have a plus/minus. They work with electronic properties," says Dr. Marksberry. "When someone's injured, when they have pain, when there's inflammation, those things all change, those properties..."We use the pulsed electromagnetic field to realign those charges to heal the cells."The Oska Pulse has been used on humans since 2015, but Dr. Marksberry says they know for a fact that it works on koalas as well."There was a koala during the 2015 wildfires that made the news for not responding to any pain treatments," he explains. "Our founder donated one of the prototypes to the vets there. The koala had a great response. The koala's name was Oska, so we actually adopted that as our name for the US device."Dr. Marksberry says the ten devices they sent can help treat dozens of patients, since multiple animals can use it at once, and treatment only takes a few hours each day."As long as it's next to the animal, they can still get pain relief from the device and go ahead and get normal rehabilitation treatments they've been getting," he says.For more information about the Oska Pulse or Oska Wellness, visit www.oskawellness.com. 1670

CHARLOTTE, N.C. (AP) — JPMorgan Chase says it will extend billions in loans to Black and Latino homebuyers and small business owners in an expanded effort toward fixing what the bank calls “systemic racism” in the country’s economic system. The bank said it is committing billion over the next five years toward programs that include earmarking more money for getting Black and Latino families into homeownership and providing additional financing to build affordable rental housing units. The bank said it expects the billion to help finance 40,000 additional mortgages for Black and Latino households, another 20,000 loans that will refinance mortgages and help construct 100,000 affordable rental units. 722