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BEIJING, Aug. 22 (Xinhuanet) -- Researchers have discovered how a human egg captures an incoming sperm for fertilization, paving the way to help couples suffering from infertility, according to media reports on Monday.An international team of researchers found that a sugar chain known as the sialyl-lewis-x sequence (SLeX) makes the outer coat of the egg “sticky,” which has proven to be helpful in binding the egg and the sperm.As a result, this observation has filled in a huge gap in the understanding of fertility and provides hope for ultimately helping couples who currently cannot conceive.Scientists and doctors know that a sperm identifies an egg when proteins on the head of the sperm match and bind to a series of specific sugars in the egg’s outer coating. With a successful match of proteins, the outside surfaces of the sperm and egg then bind together before merging, which is then followed by delivery of sperm’s DNA into egg.To identify this molecules, the researchers used ultra-sensitive mass-spectrometric imaging technology to observe and identify which molecules are most likely to be key in the binding process.They experimented with a range of synthesised sugars in the laboratory and found that it is SLeX that specifically binds sperm to an egg.According to the World Health Organisation, infertility affects about 15 percent of reproductive-aged couples around the world and almost one in every seven couples in Britain has problems conceiving a child for various reasons.

BEIJING, Aug. 12 (Xinhuanet) -- Engineers at the University of Illinois have unveiled novel, skin-mounted electronics whose circuitry bends, wrinkles, and even stretches with skin, according to media reports quoting the Science Friday.The device platform includes electronic components, medical diagnostics, communications, and human-machine interfacing on a patch so thin and durable that it can be mounted to skin much like a temporary tattoo, the jounral described.What's more, the engineers demonstrated the invention across a wider range of components, including LEDs, transistors, wireless antennas, sensors, and conductive coils and solar cells for power."We threw everything in our bag of tricks onto that platform, and then added a few other new ideas on top of those to show that we could make it work," said engineering professor John A. Rogers in a news release.
WASHINGTON, July 20 (Xinhua) -- The loss of a protein that coats sperm may explain a significant proportion of infertility in men worldwide, according to a study by an international team of researchers led by University of California Davis.A paper describing the work was published Wednesday in the journal Science Translational Medicine. The research could open up new ways to screen and treat couples for infertility.The gene DEFB126 encodes a protein called Beta Defensin 126, which coats the surface of sperm and helps it penetrate cervical mucus in the female. A survey of samples from the U.S., Britain and China showed that as many as a quarter of men worldwide carry two copies of the defective gene.In the new study, researchers found that men with a muted DEFB126 lack Beta Defensin 126, making it much more difficult for sperm to swim through the mucus and eventually join with an egg.Examining 500 newly married Chinese couples, researchers found that the lack of Beta Defensin 126 in men with the DEFB126 mutation lowered fertility (even among men that did not display other deficiencies usually associated with infertility, like inadequate semen volume and low sperm motility). Wives of men with the Beta Defensin 126 variant were significantly less likely to become pregnant than were other couples, and 30 percent less likely to have a birth.This genetic variation in DEFB126 likely accounts for many unexplained cases of infertility, researchers say. They hope next to work with a major infertility program in the U.S. to further explore the role of the mutation.
WASHINGTON, Sept. 15 (Xinhua) -- A team of researchers has discovered a planet that orbits around a pair of stars, the U.S. space agency NASA announced Thursday.This is the first instance of astronomers finding direct evidence of a so-called circumbinary planet. A few other planets have been suspected of orbiting around both members of a dual-star system, but the transits of the circumbinary planet have never been detected previously.The team, led by Laurance Doyle of the SETI Institute in California, used photometric data from the NASA Kepler space telescope, which monitors the brightness of 155,000 stars.NASA's Kepler mission has discovered a world where two suns set over the horizon instead of just one. The planet, called Kepler-16b, is the most "Tatooine-like" planet yet found in our galaxy. Tatooine is the name of Luke Skywalker's home world in the science fiction movie Star Wars. In this case, the planet it not thought to be habitable. It is a cold world, with a gaseous surface, but like Tatooine, it circles two stars.They found the binary star system by detecting a system where the stars eclipsed each other from the perspective of the Kepler spacecraft. These stars have two eclipses: A primary eclipse when the larger star is partially blocked by the smaller star and a secondary eclipse where the smaller star is fully blocked by the larger star.But the researchers also noticed other times when the brightness of the two stars dropped, even when they were not in an eclipse position. This pattern suggested that there was likely a third object involved. The fact that these so-called tertiary and quaternary eclipses recurred after varying intervals of time, and were of different depths, indicated that the stars were in different positions in their orbit at each instance. This result showed that the tertiary and quaternary eclipses were being caused by something circling both stars, and not an object circling one or the other star.Measurements of the variations in the timing of all four types of eclipses, resulting from the mutual gravitational interactions of the two stars and the third body, demonstrated that the third object was, indeed, a planet. Their work indicates that the planet is less massive than Jupiter, possibly comparable in mass to Saturn, and that the larger of the two binary stars is smaller than our Sun.Their findings will be published Friday in Science."This discovery confirms a new class of planetary systems that could harbor life," Kepler principal investigator William Borucki said in a statement. "Given that most stars in our galaxy are part of a binary system, this means the opportunities for life are much broader than if planets form only around single stars. This milestone discovery confirms a theory that scientists have had for decades but could not prove until now."
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