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The Trump Administration pushed through a million contract to study whether the active ingredient in Pepcid is an effective treatment for Covid-19. That contract is now under scrutiny after a government whistleblower accused a senior administration official of rushing the deal through without the scientific oversight necessary for such a large federal award. The Food and Drug Administration gave the clinical trial speedy approval even as a top agency official worried that daily injections of high doses of famotidine for already sick patients pushed the levels of what was considered safe “to the limits,” internal government emails show. And the doctors who initially pushed the Pepcid idea are locked in a battle for credit and sniping over allegations of scientific misconduct.The origins of the interest in famotidine are under dispute, but there were reports out of China that patients who took the drug survived the virus, while patients who took other heartburn medications were not surviving. Initial observational studies in the U.S. were promising, however scientists urged more research was needed. Meantime, the trial itself that was part of the million contract is on pause due to a shortage of hospitalized COVID-19 patients in New York, delaying it indefinitely. A vaccine or effective treatment could be available before the study is complete. 1380

The US surgeon general issued an advisory Thursday recommending that more Americans carry the opioid overdose-reversing drug, naloxone.The drug, commonly known as Narcan, can very quickly restore normal breathing in someone suspected of overdosing on opioids, including heroin and prescription pain medications.Dr. Jerome Adams emphasized that "knowing how to use naloxone and keeping it within reach can save a life." To make his point, Adams relied on a rarely used tool: the surgeon general's advisory. The last such advisory was issued more than a decade ago and focused on drinking during pregnancy.Adams noted that the number of overdose deaths from prescription and illicit opioids doubled in recent years: from 21,089 deaths across the nation in 2010 to 42,249 in 2016.America's top doctor attributed this "steep increase" to several contributing factors, including "the rapid proliferation of illicitly made fentanyl and other highly potent synthetic opioids" and "an increasing number of individuals receiving higher doses of prescription opioids for long-term management of chronic pain.""Research shows that when naloxone and overdose education are available to community members, overdose deaths decrease in those communities," Adams said. Naloxone is used by police officers, first responders and emergency medical techs to reverse opioid overdoses. Adams added that increasing both the availability of naloxone and effective treatment is critical to ending the opioid epidemic.Speaking at the National Prescription Drug Abuse & Heroin Summit in Atlanta on Thursday morning, Adams addressed the potential "moral conflict" felt by some people who believe that providing naloxone "doesn't make a difference," since many people with drug addictions will just "go on and misuse substances again.""Well, that would be like me saying 'I'm not gonna go do surgery on this trauma patient because they're just gonna go out and speed again,' " he said.Adams noted that in most states, people who are or who know someone at risk for opioid overdose can get trained to use naloxone properly and also may receive naloxone by "standing order" -- without a prescription -- from pharmacies or some community-based programs."No mother should have to bury their child ,and especially not when there's a life-saving medication that virtually anyone can access," Adams said. "It is for this reason that I am issuing the first Surgeon General's Advisory in 13 years."The-CNN-Wire 2484

The Wisconsin State Patrol pulled a driver of a sedan on Sunday because officers deemed the car was not safely transporting a snowmobile that the driver had tied to the top.The driver was on US 63 in Polk County when police flagged them down. The state trooper managed to get a photo of the vehicle.That photo was shared with the Wisconsin Department of Transportation (DOT), who then shared it on their Facebook page."Don't try this at home," the DOT said in the post. 477

The United States Consumer Product Safety Commission (CPSC) is recalling nearly half a million Kidde smoke detectors, saying they could fail to work in the event of a fire.According to the CPSC, anyone with a Kidde smoke alarm should remove their alarm from the ceiling or wall and look for a yellow cap on the inside of the alarm (see photo above). Those who find a yellow cap should contact Kidde for a replacement, and should not try and remove the yellow cap.Those who do not find a yellow cap in their smoke alarm can continue using the device normally.The alarms were sold at Menards, The Home Depot, Walmart, Amazon and Kidde's website between September 2016 and this January.The following models are covered in the recall:PI9010 (DC/battery powered)Date code: 2016 Sep. 10 through 2017 Oct. 13PI2010 (AC/hardwired)Date code: 2016 Sep. 10 through 2017 Oct. 13If you are covered by the recall, contact Kidde toll-free at 833-551-7739 from 8:30 a.m. to 5 p.m. ET Monday through Friday, or from 9 a.m.to 3 p.m. on Saturday and Sunday. You can also visit online at www.kidde.com and click on “Product Safety Recall” for more information. 1168

The Wisconsin Division of Criminal Investigation (DCI) identified Rusten Sheskey as the officer who shot Jacob Blake seven times in the back in Kenosha, Wisconsin on Sunday.The DCI, which provided its first update on the case late Wednesday, nearly 72 hours after the shooting, said its continuing its investigation, but is not pressing charges as of now.The shooting has prompted massive unrest in Kenosha since. The unrest culminated in a shooting incident that killed two people and injured one person on Tuesday amid the late-night demonstration. A 17-year-old was arrested in connection to Tuesday's shooting.In response to Sunday’s shooting, professional athletes in multiple sports boycotted scheduled games. All three NBA Playoff games on Wednesday were postponed, and a MLB game between the Milwaukee Brewers and Cincinnati Reds was also postponed.Investigators said that Sheskey, who was placed on administrative leave, has been with the police department for seven years.The DCI gave the following description of Sunday’s incident:“During the incident, officers attempted to arrest Jacob S. Blake, age 29. Law enforcement deployed a taser to attempt to stop Mr. Blake, however the taser was not successful in stopping Mr. Blake. Mr. Blake walked around his vehicle, opened the driver’s side door, and leaned forward. While holding onto Mr. Blake’s shirt, Officer Rusten Sheskey fired his service weapon seven times. Officer Sheskey fired the weapon into Mr. Blake’s back. No other officer fired their weapon. Kenosha Police Department does not have body cameras, therefore the officers were not wearing body cameras.”Officials also said that Blake told officers he had a knife. The DCI said that officials later found a knife on the driver's side floor of the car.The only videos of the incident were take bystanders that showed Blake opening his car door before he was shot at a close distance by Sheskey.Blake’s family said on Tuesday that the 29-year-old is partially paralyzed, but was fortunate to survive from his injuries. 2048