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HONG KONG, July 19 (Xinhua) -- A gene controlled by male hormone was critical for the growth of liver tumor, leading to a higher incidence of the disease in men than in women, according to the Chinese University of Hong Kong which made the results public on Tuesday.There is a significant gender bias in liver cancer incidence. In Hong Kong, men are three times more likely to develop liver cancer than women. Such phenomenon prompted researchers from the university to carry out a genomic location analysis in liver cancer cells starting from 2008.The researchers discovered, out of 17,000 human genes, that a gene called Cell Cycle-Related Kinase (CCRK) was directly controlled by androgen receptor. They further found that CCRK was critical for the induction of signaling pathway leading to abnormal liver cell growth and tumor formation.The results also reveal that 70 percent of patients with liver cancer were found to produce high levels of CCRK. More importantly, these patients were more likely to have late-stage cancers and lived shorter than those with low CCRK level.Using mouse models, the researchers found that either lowering the level or blocking the signaling pathway of CCRK in liver cancer cells could significantly reduce the tumor growth rate.The study has validated that CCRK is an important gene that has potential to cause liver cancer and the gene can be tested as a new targeted therapy in future.Vice-Chancellor of the university Joseph Sung, who is also team leader of the research project, said the results explained why men have a higher risk of liver cancer than women and helped push ahead with the development of a novel treatment of the disease.The above study results were published online in July in Journal of Clinical Investigation.

MOSCOW, Sept. 16 (Xinhua) -- A Russian Soyuz space capsule carrying three astronauts returned to the Earth Friday, the Mission Control Center outside Moscow confirmed.The three astronauts, two Russians and one American from the International Space Station (ISS), who were flown back by a Soyuz TMA-21 spacecraft, were in good condition, search and rescue teams on the ground in Kazakhstan said.Russian TV images showed the three ISS crew members being taken out of the space capsule and seated in armchairs with blankets to re-adapt to the Earth's gravity.According to the Cosmonaut Training Center, the astronauts underwent physical examinations immediately after the landing, which included examinations of hearts, lungs and adrenal glands.Seventeen helicopters and planes had waited for the capsule's landing.Helicopters will carry the astronauts from the landing site to the Kazakh city of Karaganda, from where the two Russian cosmonauts Alexander Samokutyayev and Andrei Borisenko will fly back to Moscow later Friday, while NASA astronaut Ronald Garan will leave directly for the United States for post-mission rehabilitation, the Itar-Tass news agency reported.The return of the three crew members was originally scheduled for Sept. 8, but was postponed by a failed launch of the Progress cargo ship on Aug. 24.The three crew members remaining on board the ISS are scheduled to return in mid-November.

WASHINGTON, Aug. 24 (Xinhua) -- Online search engine Google Inc. has agreed to pay 500 million U.S. dollars to settle claims that it allowed online Canadian pharmacies to place advertisements targeting consumers in the United States, U.S. Justice Department announced Wednesday.The settlement, one of the largest ever in the United States, represents the gross revenue received by Google as a result of Canadian pharmacies advertising through Google's AdWords program, plus gross revenue made by Canadian pharmacies from their sales to U.S. consumers.The advertisements led to illegal imports of prescription drugs into the country, the Justice Department said.The shipment of prescription drugs from pharmacies outside the United States to customers in the United States typically violates the Federal Food, Drug and Cosmetic Act and in the case of controlled prescription drugs, the Controlled Substances Act.Google was aware as early as 2003, that generally, it was illegal for pharmacies to ship controlled and non-controlled prescription drugs into the United States from Canada."The Department of Justice will continue to hold accountable companies who in their bid for profits violate federal law and put at risk the health and safety of American consumers," Deputy Attorney General James Cole said in a statement."This settlement ensures that Google will reform its improper advertising practices with regard to these pharmacies while paying one of the largest financial forfeiture penalties in history," he said.Google had previously set aside that amount for a possible settlement over its advertising practices, according to a regulatory filing in May.

LOS ANGELES, June 7 (Xinhua) -- Salmonella, not E. coli, poses the greatest health threat to Americans, the U.S. Centers for Disease Control and Prevention (CDC) announced on Tuesday.Salmonella infections have risen 10 percent over the past 15 years, while several types of foodborne illness have been falling, the agency said in a report.Infections from Shiga toxin-producing E. coli O157 (the strain of most concern in the United States) have dropped almost in half and the rates of six other foodborne infections have been cut 23 percent, the CDC said.The agency issued the report as a deadly new strain of E.coli is spreading in several European countries."There are about 50 million people each year who become sick from food in the U.S.. That's about one in six Americans," CDC director Dr. Thomas R. Frieden said.The CDC attributed the reduction in infections from E. coli O157 to better detection and investigation of outbreaks, cleaner slaughterhouse methods, better testing of ground beef for E. coli, improved inspections of ground beef processing plants, regulations prohibiting E. coli O157 in ground beef and increased awareness of the importance of properly cooking beef.Other foodborne illnesses that fell in incidence over the same time period include those caused by the campylobacter, listeria, vibrio and yersinia pathogens.To reduce their risk of foodborne illness, people should assume that raw chicken and other meat have bacteria that can make you sick, the CDC said.In the kitchen, raw meats should not allow to contaminate counter tops or cutting boards and should be kept away from other foods, such as fruits and vegetables, the CDC advised.The agency also called on people to thoroughly cook meat, poultry, eggs and shellfish, while refraining from consuming unpasteurized milk, juice or soft cheese.

BEIJING, Aug. 16 (Xinhuanet) -- It is widely accepted that obesity leads to an increased risk of health complications, but new studies quoted by media Tuesday challenge the conventional notion.“Our studies challenge the idea that all obese individuals need to lose weight,” said Dr. Jennifer Kuk, assistant professor in York University’s School of Kinesiology & Health Science in Toronto.  One of the studies used data from the Aerobics Center Longitudinal Study consisting of 29,533 individuals and assessed their mortality in 16 years.It found no difference in death risks between normal-weight individuals and obese ones. "Since the obese people did not have greater risk of dying than normal weight individuals, they don’t need to lose weight," said Dr. Kuk.But the finding did not give obese individuals a “free license” to gain weight, Dr. Kuk added. Maintaining weight, eating right and exercising may be better than trying to lose weight in the long run, said Dr. Kuk.

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