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SAN DIEGO (KGTV) — A San Diego-based biotech company appears to be making huge strides with its experimental COVID-19 vaccine after testing it on monkeys.Inovio Pharmaceuticals is one of more than 100 companies working on a vaccine. It’s one of few to make it to human clinical trials.“We’re much closer to finding a safe and effective vaccine,” said Dr. Kate Broderick, the VP of Research and Development for Inovio. “We’re so excited and feel so confident about the results we’ve got both in animals and our human clinical trials.”Broderick said clinical trials had shown positive results regarding the safety of Inovio’s experimental vaccine.“Our phase one has been our U.S. based trial, and we’re about to start a trial in China,” she said. “We really are looking to test the vaccine all over the world. The immune responses that these people have generated after getting the vaccine, we’re so pleased with those because they’re really broad.”She said the latest positive development came from testing the vaccine on monkeys in what’s called an Animal Challenge Study.“Those monkeys received their vaccine, then just after four months later they received the virus itself, we were able to show they were protected from that,” she said. “What we were able to show in the lungs, and the nose is that those monkeys really were protected from the symptoms of COVID-19.”It will take some time to ensure all testing is done correctly, and the potential vaccine is safe before it is given to the general public.“Realistically we should be looking at a vaccine being available for certain members of the public at the end of 2021,” she said. “Most vaccines historically take 5 to 10 years to be generated and developed; this is really a short time frame.”Broderick, a busy working mom with two young kids at home, hopes the positive results will ease the minds of those anxiously waiting to get back to normal.“I do just want to let you know there is light at the end of the tunnel; there is hope out there,” she said. “Our vaccine is looking very promising there’s other vaccines out there that are looking very good.” 2123

SAN DIEGO (KGTV) - A sign advertising a block party at the home of a registered sex offender is causing concern in Rancho Bernardo.“We would like to invite you and your kids to a neighborhood get together” read the sign, which was posted outside a home on Bernardo Oaks Drive in the Seven Oaks retirement neighborhood this week.“I always keep an eye on that house because I know there’s a registered sex offender that lives there,” said Susan Sutherland.Sutherland told 10News she looked up her community on the Megan’s Law website four years ago and found a listing for a neighbor who had had been convicted of lewd acts on a child under 14, according to Sutherland“I come from a background of abuse. I can’t live with myself if I allow a child to get hurt. I can’t live with that,” Sutherland said.The sign was posted by the contractor who recently renovated the home, which is owned by the man's mother. 10News reached out to Elor Energy, which said it had no prior knowledge of the man's past. The company canceled the event and removed the sign. 1073

SAN DIEGO (KGTV) -- A teen is fighting for his life at Sharp Memorial Hospital after he was hit by a Jeep while riding his bike in Clairemont.According to CHP officers, the accident happened just before 9 p.m. on Saturday. Officers say a Jeep was getting onto the freeway at the Clairemont Mesa Boulevard on-ramp to the 805-N when he hit the teen riding his bike. The driver says he never saw the teen until it was too late. According to officers, the teen was not in a designated cross walk, but near it. The driver of the Jeep stayed on scene, his passenger jumped out to perform CPR while paramedics arrived.The teen suffered life threatening injuries. Drugs or alcohol are not suspected in the crash 712

SAN DIEGO (KGTV) — A teenager was injured after jumping from an Uber driver's vehicle on Interstate 8 in Mission Valley late Tuesday.The 13-year-old boy, who's from Yucalan, Mexico, was traveling on westbound Interstate 8 in an Uber ordered by his father at about 9:20 p.m., according to San Diego CHP officials. Due to a language barrier with the Uber driver, the teenager decided to jump from the vehicle on the transition ramp to northbound State route 163, CHP officials said.The teen was taken to Rady Children's Hospital with minor injuries, according to San Diego Police.Based on the statements taken by officers, CHP said they are not pursuing the incident as a criminal matter at this time. 707

SAN DIEGO (KGTV) — A series of shows hitting San Diego marquees this weekend are bound to make you laugh, cry, sing, and dance!San Diego Theater Week ends this weekend, bringing a variety of shows to San Diego stages throughout the weekend and showcasing works from more than 30 performance agencies.Circus Vargas returns to San Diego for another weekend, this time at Westfield Plaza Bonita, to showcase a variety of high-flying and unusual acts of strength and agility under the big top!RELATED: Things to do for free in San Diego CountyThe California Ballet Company will host Ballet & Beer in North Park, where guests can enjoy new dances and choreography produced by the company, alongside a glass of their favorite beer. And metal-heads who are looking for a slice of tranquility won't want to miss out on Metal Yoga in Kearny Mesa.Here's a look at what's happening this weekend around town:THURSDAY4th annual San Diego Theater WeekWhere: Various locations; Cost: -(Runs Thursday - Sunday) More than 30 local performing arts organizations have come together to offer a variety of special promotions and shows during San Diego Theater Week, spanning everything from drama and comedy to musicals and theater.International Guitar NightWhere: California Center for the Performing Arts, Escodido; Cost: -Italian musician Luca Stricagnoli alongside French guitarists Antoine Boyer and Samuelito and Turkish guitarist Cenk Erdogan will put their amazing skills on display during International Guitar Night in Escondido. Their performances will highlight the diversity and craft of acoustic guitar playing with awe-inspiring shows from some of the world's best.FRIDAYCircus Vargas Where: Westfield Plaza Bonita; Cost: - (Runs Thursday - Sunday) The Big Top is back for another weekend in San Diego as Circus Vargas hits Westfield Plaza Bonita! Acrobats, daredevils, and flying trapeze artists will perform to audiences' delight, recreating circus feats from the past for a new audience.Toddler Time finger paintingWhere: The New Children's Museum; Cost: Free with museum admissionTake you little ones to the New Children's Museum for Toddler Time, including finger painting, story time, and more fun for your kids allowing them to interact with others through songs, dancing, and playtime.SATURDAYBeer & BalletWhere: The Observatory; Cost: -Enjoy the compelling choreography from the California Ballet Company and get to mix and mingle with the company's dancers after the show over beer at North Park's Observatory.Randy Jones Run/Walk for Independence 5KWhere: Crown Point Park; Cost: -Hit the pavement to help benefit thousands of men, women, and children with developmental and intellectual disabilities through Home of Guiding Hands during the annual Randy Jones Run/Walk for Independence. Stick around after the run and meet the former Padres' great himself!Chocolate WalkaboutWhere: Mirilani Makers’ District, 8665 – 8680 Miralani Dr.; Cost: VariesWhat goes better with February than chocolate? Breweries and distilleries in Miramar's Mirilani Makers' District will feature chocolate in their monthly walkabout, showing off their creativity by incorporating the ingredient into drinks and eats.Engineering Day at the MallWhere: Chula Vista Center Mall; Cost: FreeAllow your kids to learn about engineering and science through hands-on experiences at Engineering Day at the Chula Vista Center Mall. Projects will be geared toward youg students and basic concepts to expose students to fun problem solving in an interactive setting. San Diego Metal YogaWhere: Societe Brewing Company; Cost: Namaste to the sounds of Sabbath, Black Breath, and other metal bands at Societe Brewing for Metal Yoga. Classes are led by a certified instructor with a taste of metal. Tickets get you a beer and yoga session built for all skill levels.Snow DayWhere: Grossmont Center; Cost: FreeEnjoy a day of snow in La Mesa without having to head to the mountains! Grossmont Center will host some snowy fun with games for the whole family, and prizes including lift tickets and ski lessons!SUNDAYHarlem GlobetrottersWhere: Pechanga Arena; Cost: -3(Friday & Sunday) This isn't your normal basketball game. The legendary Harlem Globetrotters hit the court at Pechanga Arena in a one-of-a-kind show of amazing basketball skill and entertainment. The team's new fan-powered mobile app lets guests become a part of the action more than ever before!Oscars Viewing PartyWhere: Pacifica Del Mar; Cost: VariesExperience all the glitz and glam of the Oscars in San Diego at Pacifica Del Mar's Oscars viewing party! Enjoy ocean views, a red carpet, all-night Happy Hour, and games for prizes!Paint Your PetWhere: Lovejoy Creations Studios, Liberty Station; Cost: (Runs Saturday - Sunday) Cement you love for your pet through art during Paint Your Pet classes at Liberty Station. You'll be painting off a photo of you pet, so make sure you grab a good shot, as a guided instructor helps you create your masterpiece! In certain classes, you can even bring you own champagne — orange juice will be provided in that case.Awesome '80s RunWhere: Embarcadero Marina Park South; Cost: -Everybody lace up tonight — well, Sunday morning. The Awesome '80s Run encourages run to break out your best '80s gear and hit the course at Embarcadero Marina Park for tons of music, dancing, entertainment, and running.Aziz AnsariWhere: Copley Symphony Hall; Cost: -3Comedian Aziz Ansari hits San Diego to two laugh-packed shows at Copley Symphony Hall as part of his Road To Nowhere tour! Tickets are still available to catch one of the biggest acts in comedy today. 5686