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SAN DIEGO (KGTV) — At least six companies are working on COVID-19 vaccine candidates in San Diego, all within a 1.5-mile radius of where the I-5 and I-805 split.Locally, the farthest along appears to be Inovio Pharmaceuticals, which plans to launch a Phase 2 trial next month, potentially with a simultaneous Phase 3 trial. A Phase 3 trial is the final step in vaccine testing, with thousands of participants.The company is developing the vaccine using a DNA technique that isn’t used in any other vaccines on the market, although some are in the final stages of testing, said Dr. Kate Broderick, who leads Inovio’s vaccine program.To ensure the DNA enters a person’s cells, the company uses a proprietary device about the size of a toothbrush to deliver doses into the skin rather than a needle and syringe. The company announced Tuesday it secured a million grant from the Department of Defense to speed up production of the devices.Just down the street, TriLink Biotechnologies is working with researchers in London on a vaccine candidate that replicates itself in the body. It just started a Phase 1 trial this month.Nearby, Sorrento Therapeutics is working on both a COVID-19 vaccine and a treatment, but it hasn’t advanced yet to human trials. 10News previously featured the company’s efforts, which are based on techniques developed to fight cancer.On the other side of the 805, Arcturus Therapeutics is working with Duke University on a vaccine based on RNA, which acts as a messenger for DNA. There are no vaccines approved for humans that use this RNA approach. Trials are expected to begin in August, according to a tracker by the Milken Institute.UC San Diego is developing a vaccine using plant virus nanotechnology, leveraging an approach that’s used in vaccines against Hepatitis B and shingles. The university is also taking part in research on a COVID treatment.A spokeswoman for San Francisco-based Vir Biotechnology says the company is using its San Diego satellite office to help crunch data for the work on its vaccine, which is a collaboration with GlaxoSmithKline (GSK).GSK, Janssen, and Pfizer each have vaccine candidates of their own and offices near the 5-805 split, but 10News was not able to immediately confirm if any of those companies were conducting COVID research locally. 2318

SAN DIEGO (KGTV) - Bringing the entire family out for a day at the fair can get expensive. That's why the San Diego County Fair has set up some sweet deals for families.The biggest deal offered is the fair's season pass, which gives guests admission on all 26 days for . Which means the savings start of day two for adults and day three for children and seniors.One discount many locals expect every year is right at the checkout line. Albertsons and Vons grocery stores will sell discounted tickets at for adults and for seniors and children. Customers must have a minimum purchase of .RELATED: What to know about 2018's San Diego County FairThe grocery stores are also selling tickets for fair days, which are held on June 1, June 2, and June 6. The Passport to Savings book also includes a free return ticket to the fair. The coupon books sell for ahead of time and regularly, and include an array of coupons to use inside and outside the fair.And of course, the fair's Pay One Price Ride Days returns, offering unlimited rides for a flat rate on June 6-7, 13-14, 20-21, and 27-28.There are a number of other ways to save on tickets: 1187

SAN DIEGO (KGTV) - Cold temperatures and strong winds across San Diego County Monday prompted several weather advisories for the region. 144

SAN DIEGO (KGTV) - Another storm arrived San Diego County Wednesday, putting fire-ravaged communities at risk of flooding. Cal Fire and county officials made free sandbags available to protect homes and property.Residents should check their homes to make sure drainage areas are clear of debris. Rain can also cause erosion in areas stripped of landscaping.Anyone who needs sandbags should check the list of locations provided by County Newscenter and call ahead for availability. County officials also say you should bring a shovel to fill your own bags with sand.Sand and BagsBonita/Sunnyside: 4900 Bonita Road, Bonita, CA 91902 P: 619-479-2346Boulevard: 40080 Ribbonwood Road, Boulevard, CA 91905 P: 619-390-2020De Luz: 39524 Daily Road, Fallbrook, CA 92028 P: 760-728-3140 *(Not staffed 24/7)De Luz: 39431 De Luz Road, Fallbrook, CA 92028 P: 760-728-2422Fallbrook: 4375 Pala Mesa Drive, Fallbrook, CA 92028 P: 760-723-2024Lakeside River Park Conservancy:12108 Industry Road, Lakeside CA 92040 P: 619-443-4770 *(Closed over the weekend)Palomar Mountain: 21610 Crestline Road, Palomar Mtn., CA 92060 P: 760-742-3701Ramona: 3410 Dye Road, Ramona, CA 92065 P: 760-789-0107Ramona: 24462 San Vicente Road, Ramona, CA 92065 P: 760-789-9465Rincon: 16971 Highway 76, Pauma Valley, CA 92061 P: 760-742-3243Valley Center: 28205 N. Lake Wohlford Road, Valley Center, CA 92082 P: 760-751-7605Warner Springs: 35227 Highway 79, Warner Springs, CA 92086 P: 760-782-9113Bags OnlyAlpine: 1364 Tavern Road, Alpine, CA 91901 P: 619-445-2635Deer Springs: 1321 Deer Springs Road, San Marcos, CA 92069 P: 760-741-5512Campo: 31577 Highway 94, Campo, CA 91906 P: 619-478-5516Campo (Lake Morena): 29690 Oak Drive, Campo, CA 91906 P: 619-478-5960Deer Springs: 8709 Circle R Drive, Escondido, CA 92026 P: 760-749-8001Deer Springs: 10308 Meadow Glen Way East, Escondido, CA 92026 P: 760-751-0820De Luz: 39431 De Luz Road, Fallbrook, CA. 92028 P: 760-728-2422Descanso: 24592 Viejas Grade Road, Descanso, CA 91916 P: 619-445-7508 (currently out of bags)Dulzura: 17304 Highway 94, Dulzura, CA 91917 P: 619-468-3391El Cajon: 551 Harbison Canyon Rd, El Cajon, CA 92019 P: 619-445-5001Escondido: 9127 W. Lilac Road, Escondido, CA 91916 P: 619-445-7508Jacumba: 1255 Jacumba St., Jacumba, CA 91934 P: 619-766-4535Jamul (Deerhorn): 2383 Honeysprings Road, Jamul, CA 91935 P: 619-468-3030Jamul: 14024 Peaceful Valley Ranch Rd, Jamul, CA 91935 P: 619-669-6580Julian: (Shelter Valley) 72160 Great Southern Overland, Julian, CA 92036 760-765-0155Mount Laguna: 10385 Sunrise Highway, Mt Laguna, CA 91948 P: 619-473-8281Ocotillo Wells: 5841 Highway 78, Borrego Springs, CA 92004 P: 760-767-7430Pine Valley: 28850 Old Highway 80, Pine Valley, CA 91962 P: 619-473-8445Portrero: 25130 Highway 94, Potrero, CA 91963 P: 619-478-5544Ramona: 829 San Vicente Road, Ramona, CA 92065 P: 760-789-8914Ramona: (Intermountain) 25858 A Highway 78, Ramona, CA 92065 P: 760-789-3710Ramona: (Mount Woodson) 16310 Highway 67, Ramona, CA 92065 P: 760-789-1150Ranchita: 37370 Montezuma Valley Road, Ranchita, CA 92066 P: 760-782-3467 *(Not staffed 24/7)San Pasqual: 17701 San Pasqual Valley Rd, Escondido, CA 92025 P: 858-573-1322Warner Springs: 31049 Highway 79, Warner Springs, CA 92086 P: 760-782-3560 3251

SAN DIEGO (KGTV) -- Authorities eradicated a massive illegal marijuana grow operation discovered near a popular trail in the Rancho Pe?asquitos area.According to Drug Enforcement Administration officials, San Diego police officers were called out to an area of the Del Mar Mesa Preserve on Tuesday regarding a homeless encampment. That’s when they discovered more than 2,000 marijuana plants.The plants were 5- to 7-feet tall and were ready to be harvested. The street value of the crop is estimated to cost as much as .5 million, the DEA said.The plants were hidden below the canopy of the natural vegetation.“The way that it was set up, it was obvious people were living on that property, would lead us to believe, if we had to make a guess, it was most likely cartel-related,” DEA officials said.They called it a sophisticated operation, adding it was rare to see an illegal grow of its size growing in a city so close to homes.“In this case, we think it's more likely they found a fire hydrant or some sort of a city water source that they were able to tap into,” DEA officials said. “We couldn’t find that in this case, but we think that’s the most likely scenario.”Authorities said there was also an extreme fire danger associated with the grow. They found trash in the vicinity, as well as two propane tanks and open flame burners for cooking in an area with tall, dry vegetation.Authorities have not found anyone connected to the illegal operation. They are asking the community with any information to come forward. 1534

来源：资阳报