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Dr. Anthony Fauci delivered more good news regarding a potential coronavirus vaccine, indicating some Americans could begin getting vaccinated by the end of this month.During an interview with CNN’s Wolf Blitzer, Fauci, the director of the National Institute of Allergy and Infectious Diseases National Institute of Allergy and Infectious Diseases, said it’s possible a vaccine could begin reaching some Americans by the end of the month, but was confident some would begin getting vaccinated by the end of the year.Fauci’s declaration came on the same day Pfizer said that its Phase 3 vaccine candidate was showing an effectiveness of over 90%. Fauci said the announcement was promising, but a few more questions need to be addressed before it is given approval. Fauci said that things like the vaccine’s durability and effect on the elderly are among concerns that still need to be tackled.“We may have doses that we’re able to give to people by the end of November, beginning of December,” Fauci told CNN’s Blitzer. “Now you have to go through the hoops of making sure all of the I’s are dotted and the T’s are crossed about the safety and regulatory aspects of it, but we would be giving vaccine, very likely, by the end of this year. That is good news.”Last month, the FDA put into place guidelines on approving a vaccine, which was more restrictive than what the White House had hoped for. The FDA noted that a vaccine candidate must be at least 50% effective. Vaccine candidates should include a median follow-up duration of at least two months after completion of the full vaccination regimen to help provide adequate information to assess a vaccine’s risk-benefit.“In addition to outlining our expectations for vaccine sponsors, we also hope the agency's guidance on COVID-19 vaccines helps the public understand our science-based decision-making process that assures vaccine quality, safety and efficacy for any vaccine that is authorized or approved,” Peter Marks, M.D., Ph.D., director of the FDA's Center for Biologics Evaluation and Research, said.While it is possible some will begin getting vaccinated in the coming weeks or months, questions remain on how soon a majority of the country will have the opportunity to become vaccinated. The first Americans slated to become vaccinated will be health care workers and people with a high risk of coronavirus complications, such as the elderly and those living in assisted living facilities, according to an NPR report.Given that Pfizer’s vaccine candidate is showing a high level of effectiveness, Fauci called the development “extraordinary.”"We know there's light at the end of the tunnel, but that doesn't mean that we're going to give up the important public health measures that we continually still have to do every single day,” Fauci said.While there is urgency for both public health and economic reasons for a vaccine, some experts have expressed concern over the speed of a vaccine and whether the expedited timeline is long enough to demonstrate efficacy.Even though a vaccine could be ready by year’s end, trials will be expected to continue for over a year to monitor for possible side effects.According to the FDA, a typical Phase 3 trial would take one to three years.“NIH is committed to supporting several Phase 3 vaccine trials to increase the odds that one or more will be effective in preventing COVID-19 and put us on the road to recovery from this devastating pandemic,” said NIH Director Francis S. Collins, M.D., Ph.D. “We also know that preventing this disease could require multiple vaccines and we’re investing in those that we believe have the greatest potential for success.”Pfizer said based on current projections, it expects to produce globally up to 50 million vaccine doses in 2020 and up to 1.3 billion doses in 2021. 3823

During an interview on Fox News on Tuesday, President Donald Trump called on Attorney General William Barr to open a corruption investigation into Joe Biden's alleged ties to Ukraine based on information contained in emails reportedly taken from a laptop that may or may not have belonged to Biden's son."We've got to get the Attorney General to act. He's got to act and he's got to act fast. He's got to appoint someone," Trump said Tuesday during an interview on Fox & Friends. "This is major corruption, and this has to be known about before the election."Trump was referring to a report first published in the New York Post last week that was based on emails allegedly recovered from a laptop left at a Delaware computer repair shop. The Post claimed the emails were taken from a laptop belonging to Biden's son, Hunter, and showed that the younger Biden was contacted by the adviser to the board of a Ukrainian energy company, Burisma. In the emails, allegedly, the Ukrainian official thanked Hunter Biden for giving him an opportunity to meet his father.Some Republicans have seized on the story, calling it a "smoking gun." They claim that such a meeting would be a conflict of interest, given Joe Biden's political influence and Hunter Biden's position on Burisma's board.However, the Post's story left several questions about the authenticity of the emails unanswered. The owner of the repair shop, where the laptop was recovered, was unable to identify the computer's owner. The shop owner did say a Beau Biden Foundation sticker was attached to the computer. There's also no evidence that Hunter Biden responded to the email from the Ukranian energy advisor. The Biden campaign says the former Vice President's schedule shows no meetings with that advisor. Finally, the Post said it obtained materials and information for the story from Rudy Giuliani, one of Trump's personal lawyers.Citing sources, The New York Times reported Monday that one of the Post journalists who wrote the story asked that his name not be attached to the article "because he had concerns over the article's credibility."Despite Trump's claim that the emails show Joe Biden has an inclination to use his political office for personal enrichment, Trump and his family have an extensive history of dubious business practices. The New York Times reports that Trump has leveraged the office of the presidency to drive business to his resorts and hotels.Trump's call to action to Barr is just his latest call for the neutral agency to delve into cases that would be politically advantageous to the president. Earlier this month, Trump said he was "disappointed" in Barr for his inaction on voter fraud investigations and his inability to recover emails deleted by Hillary Clinton prior to the 2016 election.Weeks ago, 1,600 former Department of Justice lawyers signed an open letter that claimed Barr was abusing the power of his office to help Trump win reelection. 2959

Dr. Anthony Fauci, the nation's top infectious disease expert, called for the U.S. to "double down" on what he called "common-sense" public health measures on Monday as the country faces a critical juncture amid the COVID-19 pandemic.After enormous surges in cases in the spring and summer, the U.S. was able to flatten the curve a bit in early September. According to Johns Hopkins, the U.S. dropped to a low point of about 34,000 new daily cases of COVID-19, down from a high of about 70,000 new cases in July.However, case rates have increased gradually in recent weeks, and Fauci warned that Americans need to take public health measures seriously as cold weather forces many indoors, adding that the country is "not in a good place" ahead of winter."(Some states) are starting to show upticks in cases and even some increase in hospitalizations in some states," Fauci said Monday during an appearance on ABC's Good Morning America. "You don't want to be in a position like that as the weather starts getting cold."Fauci added that despite the increase in cases, he did not believe the U.S. needed to go into another total lockdown similar to the one that took place in March and April."I would really like to not go there because it causes so many collateral issues and problems," Fauci said. "...obviously, if things really explode, you'd have to consider that. But we want to do everything we possibly can to avoid an absolute shutdown. In other words, get the cases under control by the common-sense types of things that we've been talking about all along, those public health measures."However, Fauci said he was "concerned" by Florida's decision to reopen bars and restaurants. On Friday, Florida Gov. Ron DeSantis moved the state into "Phase 3" of its reopening plan, meaning that restaurants, bars and hotels can operate at full capacity. Local governments are also unable to restrict a business' operating capacity unless granted permission by the state.Fauci said he was specifically troubled by the state's reopening of bars."That is very concerning to me," Fauci said. "We have always said that — myself and Dr. Deborah Birx, who is the coordinator of the task force — that that is something that we really need to be careful about, because when you're dealing with community spread, and you have the type of congregate setting where people get together, particularly without masks, you're really asking for trouble."In the past, Fauci has advocated for five common-sense public health measures that all Americans should take amid the pandemic: Wearing masks, avoiding crowds, keeping six feet apart from others, constant hand washing and opting for outdoor activities over indoor activities. He says if the U.S. continues to follow those guidelines, the country can continue to open up the economy."If you (open the economy) in a prudent way — in a prudent way means focus on things that are important — you can open businesses, you can do things like that," Fauci said. "But when you start opening up bars without masks or congregate settings where people are indoors without masks, that's asking for trouble." 3136

During a stop for his book tour in Missoula, Montana, Monday night, former Vice President Joe Biden discussed his 2020 prospects, saying he believes that he is the "most qualified person" to be president, noting a decision is coming in the next two months, and acknowledging he's a "gaffe machine.""I'll be as straight with you as I can. I think I'm the most qualified person in the country to be president," Biden said to applause at the University of Montana. "The issues that we face as a country today are the issues that have been in my wheelhouse, that I've worked on my whole life.""No one should run for the job unless they believe that they would be qualified doing the job. I've been doing this my whole adult life, and the issues that are the most consequential relating to the plight of the middle class and our foreign policy are things that I have -- even my critics would acknowledge, I may not be right but I know a great deal about it," he added.Biden said his family must now decide as a "unit" whether or not they're prepared for a run -- setting a decision time frame of the next six weeks to two months."I have two young grandchildren my son left who love me and adore me and want me around. I want to be there to take care of them, so we've got to figure out whether or not this is something we can all do as a family," he said. "We're going to make that decision in the next six weeks to two months, and that's the basis of the decision."The moderator, Bruce Feiler, pointed out some of the potential liabilities of a Biden campaign, saying "He's too old. He signed, he cosponsored the crime bill. He was the chairman of the judiciary committee during the Anita Hill hearings, and he's out of touch in the era of Me Too. .5 million ain't gonna cut it anymore, you need 0 million. Who wants to wake up at 6 a.m. for the next two years and get insults from the President of the United States?...You're a gaffe machine. I could go on. Which of these scares you the most?""None of them," Biden said before moving on to defend some of those potential liabilities."I am a gaffe machine, but my God what a wonderful thing compared to a guy who can't tell the truth," he said. "I'm ready to litigate all those things, the question is what kind of nation are we becoming? What are we going to do? Who are we?""Whether or not I run, whoever runs, I'm going to break my neck to make sure they win," he said. "We can't have four more years."Earlier in the night, Biden discussed some of the missteps of his 1988 presidential campaign, including accusations of plagiarism while he was in high school."It all came out in the wash -- I never did plagiarize, I never did -- and it all was proven that that never happened," Biden said.However, in 1987, Biden acknowledged that he had plagiarized part of a law school paper.The-CNN-Wire 2854

EL CAJON (CNS) - A young woman who allegedly stabbed her grandmother in El Cajon, leaving the victim hospitalized with serious injuries, was charged Friday with attempted murder, dissuading a witness and resisting arrest.Elektra Zaya Del Sol, 20, of El Cajon, faces a potential life sentence if found guilty of the stabbing attack that occurred shortly before 10:30 a.m. Wednesday in the 1200 block of North Mollison Avenue.READ: Woman arrested for reportedly stabbing grandmother in El CajonParamedics took the victim, whose name and age were not released, to a hospital for treatment of life-threatening injuries, El Cajon Police Department Sgt. Will Guerin said. After questioning her granddaughter, detectives arrested Del Sol on suspicion of carrying out the assault.Police did not disclose a motive for the assault, though the 911 caller who reported it said it occurred during a burglary, according to Guerin.Police did not disclose a motive for the assault, though the 911 caller who reported it said it occurred during a burglary, according to Guerin.Del Sol, who also faces allegations of using a weapon in the attempted slaying and inflicting great bodily injury on an elder, pleaded not guilty and was being held without bail. She is set to return to court April 17 for a readiness conference. 1313

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