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BEIJING, July 26 (Xinhuanet) -- Seven of the 20 top selling American prescription drugs will lose their patents by the end of next year, making way for less expensive generic versions, according to media reports.It's a shift that could save consumers billions of dollars -- assuming those big-ticket medications are willing to give up a trusted brand name for an off-label replacement.The prices of medications such as cholesterol-fighting Lipitor and blood thinner Plavix are expected to go down significantly, according to the U.S. Food and Drug Administration (FDA).Lipitor will lose its patent in November. When that patent expires, people are advised to buy atorvastatin, the generic equivalent. Other brand names include the anti-psychotic Zyprexa and the rheumatoid arthritis and psoriasis drug Enbrel, of which the patent will expire in October and October of next year, respectively.Over the next 10 years, an estimated 120 more brand-name prescription drugs will lose their patents in the U.S.
CHENGDU, Sept. 3 (Xinhua) -- A list of this year's top 500 Chinese enterprises was unveiled in the city of Chengdu in southwest China's Sichuan Province on Saturday.The Sinopec Group was ranked first, with last year's revenues reaching 1.97 trillion yuan (307.81 billion U.S. dollars), followed by the China National Petroleum Corp. and State Grid Corp., whose revenues hit 1.72 trillion yuan and 1.53 trillion yuan last year, respectively.The rest of the top 10 was rounded out by the Industrial and Commercial Bank of China, China Mobile, China Railway Group, China Railway Construction Corp., China Construction Bank, China Life Insurance Co. and Agricultural Bank of China.The list is the 10th of its kind to be jointly released by the China Enterprise Confederation and the China Enterprise Directors Association. The threshold for entering the list was raised to 14.2 billion yuan in revenues, an increase over the 11.08-billion-yuan threshold used during the previous year.Revenues for China's top 500 companies rose 31.6 percent year-on-year to 36.31 trillion yuan in 2010, while their total assets increased by 18.4 percent to 108.1 trillion yuan, the two organizations said.The companies reported profits of 2.08 trillion yuan for last year, a rise of 38.67 percent from one year earlier.They paid 2.73 trillion yuan in taxes in 2010, accounting for 37.3 percent of the country's total tax revenues.

SINGAPORE, Sept. 7 (Xinhua) -- Singapore scientists have found possible new ways to treat a type of aggressive breast cancer that is unresponsive to current forms of treatment, local broadcaster Channel NewsAsia reported on Wednesday.The team of scientists at the Genome Institute of Singapore ( GIS) and National University of Singapore (NUS), led by GIS senior group leader Qiang Yu, found that the enzyme EZH2 acts by inhibiting genes that stop the growth of tumors in the body.The insights could open the door to developing more effective treatment for fast spreading breast cancers, especially the estrogen receptor-negative breast cancer that is common all over the world.It was also found that through EZH2, cancer is promoted in the body by activating specific genes that impact breast cancer progression and cancer stem cell self-renewal.Yu said the new understanding on how EZH2 works as a cancer- causing gene in breast cancer has important therapeutic implication."The results suggest that small molecule drugs that block enzyme activity of EZH2 may not work for cancers caused by EZH2's activation genes," Yu said.Currently pharmaceutical companies have been developing drugs only to the block EZH2 enzyme activity so that tumor suppressers can perform their protective role in blocking cancer growth.Researchers said the next step would be to develop biomarkers to identify tumors with EZH2.This step would enable better treatment methods, with one of options being the development of therapies that shut down EZH2 completely and not just inhibit its enzymatic function.The findings have been published on the journal Molecular Cell.
CANBERRA, June 10 (Xinhua) -- Going to work when you are feeling sick can make you sicker in the long run, an expert told Australia's media on Friday.New Zealand sociologist Professor Kevin Dew from the Victoria University in Wellington, has assessed more than 40 papers about " presenteeism".He defined presenteeism as: "People that are turning up at work when they feel that they should be at home sick.""People feel compelled to go to work because someone else would have to take up the workload (and they have a) feeling of responsibility for not being able to care properly for patients (if they don't show up)," he told the Australia Associated Press on Friday.He said that evidence suggested people who go to work when they are sick can have long term negative effects on health and productivity.Evidence shows that presenteeism increases illness, including musculoskeletal pain, fatigue, depression, and serious coronary events. It also leads to exhaustion which, in turn, leads to more presenteeism.Prof. Dew said certain medical conditions like depression and migraine are also linked with presenteeism because they are not seen as legitimate reasons for absence.He has written an editorial in the latest issue of the British Medical Journal about his findings.
OTTAWA, Sept. 29 (Xinhua) -- Climate change could cost Canada billions of dollars a year by the end of this decade, a government funded study group announced Thursday.The National Round Table on the Environment and the Economy said the cost of climate change for Canada could start at roughly 5 billion Canadian dollars per year in 2020 and increase to between 21 billion and 43 billion per year by 2050. Those costs would come from shoreline damage, public health problems, and disruptions to the economy.It also predicted a slight increase in deaths in major cities from heat and air pollution.The round table researchers estimated the cost of climate change is expected to be roughly 0.8 percent to 1.0 percent of GDP -- or 43 billion Canadian dollars a year -- by 2050, if the problem is allowed to worsen.But the report did not address possible benefits, such as reduced demand for hea
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