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President Donald Trump’s physical Dr. Sean Conley confirmed Friday that the president is taking an experimental antibody treatment to help him fight the coronavirus following his diagnosis this morning.Dr. Conley said Friday afternoon that Trump is "fatigued."Trump is taking the Regeneron antibody cocktail, which is currently in a clinical trial. Conley said that Trump has been treated with a single 8 gram dose, which Conley said was infused "without incident."Trump is also said to be taking Vitamin D, zinc, famotidine, melatonin and daily aspirin. The Regeneron trial has only been tried on 275 patients as of this week, but the company said earlier this week that it has showed promising results.Regeneron confirmed that Trump was given the treatment under a "compassionate use request.""In the USA, this type of compassionate use program is also known as an Expanded Access Program (EAP) and is intended for patients with serious or life-threatening conditions, who do not have any viable or available treatment options, and are unable to participate in ongoing clinical trials," Regeneron said in a statement. The plan is to enroll 2,000 patients in early studies of the treatment."After months of incredibly hard work by our talented team, we are extremely gratified to see that Regeneron's antibody cocktail REGN-COV2 rapidly reduced viral load and associated symptoms in infected COVID-19 patients," said George D. Yancopoulos, M.D., Ph.D., President and Chief Scientific Officer of Regeneron. "The greatest treatment benefit was in patients who had not mounted their own effective immune response, suggesting that REGN-COV2 could provide a therapeutic substitute for the naturally-occurring immune response. These patients were less likely to clear the virus on their own, and were at greater risk for prolonged symptoms.The treatment is a combination of two monoclonal and was designed specifically to block infectivity of SARS-CoV-2, the virus that causes COVID-19, the company said.“The two potent, virus-neutralizing antibodies that form REGN-COV2 bind non-competitively to the critical receptor binding domain of the virus's spike protein, which diminishes the ability of mutant viruses to escape treatment and protects against spike variants that have arisen in the human population, as detailed in Science.” Regeneron said in a statement. “Preclinical studies have shown that REGN-COV2 reduced the amount of virus and associated damage in the lungs of non-human primates.”According to Regeneron, the treatment has been tried on hospitalized and non-hospitalized patients and as a preventative for those who have had close contact with coronavirus patients. So far, the drug has been particularly promising for non-hospitalized patients.Regeneron said the treatment reduces the viral load from the coronavirus, and boosts the body’s immune response to the virus. 2890
President Donald Trump’s plan to offer a stripped-down boost in unemployment benefits to millions of Americans amid the coronavirus outbreak has found little traction among the states, which would have to pay a quarter of the cost to deliver the maximum benefit.An Associated Press survey finds that as of Monday, 18 states have said they will take the federal grants allowing them to increase unemployment checks by 0 or 0 a week. The AP tally shows that 30 states have said they’re still evaluating the offer or have not said whether they plan to accept the president’s slimmed-down benefits. Two have said no.The uncertainty is putting some families’ finances in peril.Tiana Chase, who runs a community game room and store in Maynard, Massachusetts, said the extra 0 she and her partner had been receiving under the previous federal benefit helped keep them afloat after the pandemic caused many businesses to shutter.For the past few weeks, she’s been getting less than 0 in unemployment. If that’s boosted by another 0, “it’s going to be a lot tighter, but at least I can vaguely manage,” she said. “I can cover my home expenses.”Many governors say the costs to states to receive the bigger boost offered by Trump is more than their battered budgets can bear. They also say the federal government’s guidelines on how it will work are too murky. Pennsylvania Gov. Tom Wolf, a Democrat, called it a “convoluted, temporary, half-baked concept (that) has left many states, including Pennsylvania, with more questions.”New Mexico was the first state to apply for the aid last week and one of the first to be announced as a recipient by the Federal Emergency Management Agency. But Bill McCamley, secretary of the state’s Department of Workforce Solutions, said it’s not clear when the money will start going out, largely because the state needs to reprogram benefit distribution systems to make it work.“People need help and they need it right now,” McCamley said. “These dollars are so important, not only to the claimants, but because the claimants turn that money around, sometimes immediately to pay for things like rent, child care, utilities.”In March, Congress approved a series of emergency changes to the nation’s unemployment insurance system, which is run by state governments.People who were out of work got an extra federally funded 0 a week, largely because the abrupt recession made finding another job so difficult. The boost expired at the end of July, and recipients have now gone without it for up to three weeks.With Democrats, Republicans and Trump so far unable to agree to a broader new coronavirus relief plan, the president signed an executive order Aug. 8 to extend the added weekly benefit, but cut it to 0 or 0 a week, depending on which plan governors choose. States are required to chip in 0 per claimant to be able to send out the higher amount, something few have agreed to do, according to the AP tally.Trump’s executive order keeps the program in place until late December, though it will be scrapped if Congress comes up with a different program. It also will end early if the money for the program is depleted, which is likely to happen within a few months.Governors from both parties have been pushing for Congress to make a deal, even after previous talks for a sweeping new coronavirus relief bill, including an unemployment boost, broke off earlier this month.When Congress finally reaches an agreement, “I have every reason to believe ... there will be a more robust deal that is struck,” said Texas Gov. Greg Abbott, a Republican who has been noncommittal about accepting Trump’s plan.One reason for the states’ hesitancy is that they fear they will go through the complex steps required to adopt Trump’s plan, only to have it usurped by one from Congress, according to a spokeswoman for Republican Wyoming Gov. Mark Gordon.So far, most states that have said they are taking Trump up on his offer have chosen the 0 version. Some have not decided which plan to take. In North Carolina, for instance, Democratic Gov. Roy Cooper has pushed for the 0 plan, but Republican lawmakers have not committed to kick in a share of state money for that.Mississippi’s Republican Gov. Tate Reeves has spurned the deal altogether, saying it’s too expensive.State leaders who say they can’t afford to chip in point to the widespread closure of businesses, which has hammered government tax revenue. But they also acknowledge that they need the help, as a record number of claims have left their unemployment trust funds in rough shape.Most states expect to exhaust their funds and need federal loans to keep paying benefits during the recession. So far, 10 states plus the U.S. Virgin Islands have done so, including California, which has borrowed .6 billion. Another eight states have received authorization for loans but had not used them as of last week.California Gov. Gavin Newsom, a Democrat, is among governors who are critical of Trump’s approach but decided to take the deal anyway. “As I say, don’t look a gift horse in the mouth,” Newsom said last week.The federal Department of Labor reported last week that 963,000 people applied for unemployment benefits for the first time. It was the first time since March that the number dropped below 1 million. The government says more than 28 million people are receiving some kind of unemployment benefit, although that figure includes some double counting as it combines counts from multiple programs.State unemployment benefits on their own generally fall far short of replacing a laid off worker’s previous income.Chris Wade, who lives in the Chicago suburb of Schaumburg, is a server at a high-end restaurant. He was laid off in March when dine-in restaurants were closed in the state. While he’s since returned, he’s working only a few shifts a week and his unemployment checks are reduced by the amount he’s paid.The now-expired 0 weekly unemployment supplement came out to about the same as his family’s rent, he said. When his first check came in April, he was eight days behind on rent, but with the help, he’s been able to keep paying since then.“The extra money, no matter what they give me, is all going to rent anyway, or other bills,” said Wade, 45. “Every dollar actually counts.”___Follow AP reporter Geoff Mulvihill at http://www.twitter.com/geoffmulvihill.___AP statehouse reporters across the U.S. contributed to this report. 6470
Receiving a wedding invitation should be exciting, not dreadful. But if it’s not the first one this season, or if you’re keeping a wary eye on your budget, getting that embossed white card in the mail could bring mixed emotions — and the search for a tactful way to decline. One-third of Americans have skipped or considered skipping a wedding because they couldn’t afford to attend, according to a recent survey from NerdWallet, conducted online by The Harris Poll. Their reluctance to attend is understandable, considering that the average reported budget for a close friend’s wedding gift was 8, according to the survey. “Many wedding guests look at a friend’s bridal registry and start doing the math,” says Courtney Jespersen, NerdWallet consumer saving expert. “But thankfully, the 0 coffee maker and 0 vacuum aren’t your only gift options.”Here are several budget-friendly wedding gifts that cost far less, or even nothing at all.Go in on a gift with a group. Other guests may be in the same boat, and if the wedding registry has gifts at various price points, there’s an opportunity for you to pool your gift budgets and choose something the couple really have their eyes on. Check with friends you know are on the guest list and choose an amount to spend that fits everyone’s budgets.Shop off-registry. You don’t have to stick to the wish list the couple put together, particularly if there’s nothing on there within your budget. “It’s perfectly fine for a guest to go off-registry,” says Diane Gottsman, national etiquette expert and founder of The Protocol School of Texas. “A registry is a useful guide that makes sure the bride and groom get what they need. However, a guest can also feel free to write a check or purchase something else they know the bride and groom will enjoy.”? MORE: 3 tips for the ideal wedding guestGive an experience. If the happy couple are millennials, there’s a good chance they’d love an experience more than a material gift anyway. Offer to plan and prepare a romantic picnic or help them build a garden in their backyard, Gottsman suggests.Contribute to a larger cause. If it’s good enough for Prince Harry and Meghan Markle, this may work for your friends, too. More than 4 in 10 (43%) millennials say they’d prefer to donate to charity in a couple’s name than buy them a registry gift, according to the NerdWallet survey. This is an appropriate gift if the couple has requested charitable contributions in their name or if you know they feel strongly about a certain cause or organization. Most charities don’t have a donation minimum, so you can spend as much or as little as you want.Help fund a honeymoon (or home). Honeymoon and even down payment funds are increasingly popular choices for couples with pending nuptials. If your friends have set up such a registry, it’s a good option for guests with fixed budgets. ? MORE: How to cut wedding guest costsGet creative. Personalized gifts often mean the most. If you’re artistic, write the couple a meaningful poem or paint them a picture. You could also pay for someone else’s creativity — getting a relatively inexpensive photo frame personalized with the wedding date or couple’s last name, for example, makes a unique gift that may come in well under the average gift budget. “A gift doesn’t have to be expensive to be significant,” Gottsman says. “The most important thing is to let the bride and groom know you’re happy for them and wishing them a lifetime of happy memories.”More From NerdWallet 3626
Prisons across the country have suddenly become ground zero for the coronavirus.In California’s oldest jail, San Quentin State Prison near San Francisco, the number of cases has ballooned from less than 100 to more than 1,000 in two weeks.Attorneys in the area say the outbreak came from a transfer of inmates from the California Institute for Men to San Quentin.In the closed system that is a prison, it can make social distancing a challenge as there is only so much space to house inmates, particularly at a distance.Prison reform advocates say to solve the problem correctional facilities nationwide have turned to solitary confinement."The reports that I’m getting back now is not ‘Hey they put me in solitary for COVID-19.’ It’s, ‘They’re keeping me in solitary because of COVID-19,’” said Johnny Perez.Perez was formerly incarcerated at Riker’s Island in New York City for an armed robbery he committed when he was 21. He served 13 years for the crime, 3 of which were spent in solitary confinement, he says.“[It gave me] thoughts of suicide, volatility in my emotions,” said Perez. “I still need to sleep with the door open at night.”Perez says the experience in solitary can be similar for most people he knows, and thinks it is a dangerous way to combat COVID-19.“[The corrections system] treating you like an animal for the rest of your life says more about our system than it does about our individuals,” he said. “It is creating and lowering this standard of what it means to be put in solitary that is so low that it reverses all the work that we’ve done so far.”Perez is the director of the U.S. Prisons Program for the National Religious Campaign Against Torture, a group that works closely with the ACLU to form Unlock the Box, a national advocacy group fighting to end solitary confinement. Unlock the Box estimates the number of people currently in solitary confinement in U.S. prisons is 300,000; a large jump from the 60,000 it says was in solitary confinement in February.“There is a perpetuation and it is a really terrible cycle,” said Jessica Sandoval, campaign strategist for Unlock the Box. “[Inmates] are not going to report that they feel bad if that’s what the prison is going to do anyway so it’s pretty dangerous.”In an emailed response the Federal Bureau of Prisons did not respond to questions about solitary confinement in response to COVID-19, but it did say other measures it was taking to reduce the spread of the virus in the prison system through universal distribution of PPE, limited visits to those incarcerated, and no inmate transfers between facilities.Sandoval says medical isolation is a better practice, which does not strip inmates of many of their privileges. She also advocates early release for inmates nearing the end of their sentences or in the process of seeking parole."I think there needs to be a reckoning among corrections leaders and governors to say we’re going to do what’s right,” said Sandoval. "We’re going to save lives."According to the National Institute of Corrections it costs ,000 to house someone in solitary confinement for a year, as opposed to ,000 to house someone in the general prison population for a year. 3201
President-elect Joe Biden has marked the 48th anniversary of the accident that killed his first wife and baby daughter by attending Mass at the church where they are buried.Neilia Biden and the couple’s 13-month old daughter, Naomi, were killed when their car was struck by a tractor-trailer as she took the kids to pick out a Christmas tree.Sons Hunter and Beau were seriously injured. They were a year and a day apart in age, at 3 and 4.Joe Biden had just been elected to the Senate and was in Washington setting up his new office at the time of the accident.Biden and his wife, Jill Biden, attended the Friday morning service in Delaware at St. Joseph on the Brandywine, a Roman Catholic church. The campus of the church contains a large parish cemetery. After Mass, the Bidens walked to the gravesite markers to pay their respects. 843