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LA JOLLA (KGTV): Researchers at the UC San Diego Moores Cancer Center and the La Jolla Institute of Allergy and Immunology have teamed up to find a new way to fight cancer.They've created a vaccine that can help teach the immune system how to attack only cancer cells and leave the rest of the body alone."Patients will be able to tolerate their therapy much better than they have so far on conventional approaches," says Dr. Stephen Schoenberger from the La Jolla Institute.Each vaccine is highly personalized to the patient. According to a release from UC San Diego, the vaccines "defines the neoantigens – foreign protein fragments recognized by the immune system – in a patient’s cancer. With neoantigens identified, the team can identify peptides – strings of amino acids – that can be used to create a vaccine to stimulate a protective immune system response."Simply put, the new vaccine takes information from a patient's immune system and the tumor and uses it to help white blood cells to fight it."We're giving them life and giving them hope," says Dr. Schoenberger.The first patient in the clinical trial is Tamara Strauss. She was diagnosed with pancreatic cancer in 2015 and went through chemotherapy and surgery."It was brutal," says Strauss. "It's been three and a half years of hell."Strauss' parents helped fund the clinical trial with a million donation. She says she feels fortunate they could do that, but also hopeful that it helps others down the road."I really pray that this vaccine and personalized form of treatment really does change the paradigm of cancer treatment," says Strauss.During the trial, ten patients will get three doses of the vaccine. They'll also be on Keytruda, an immune system boosting drug for up to two years. Their health will be monitored for five years to determine the vaccine's effectiveness. 1871
KANSAS CITY, Mo. — It's the happiest a Kansas City widower said he has been in three years."That's when our whole journey started," said Jim Purcell, who lost his 29-year-old wife Christy last year.Christy was diagnosed with brain cancer two months after their son, Jameson, was born.Scripps station KSHB in Kansas City reported earlier in April that Purcell's wedding rings had been stolen."It’s been a brutal journey. Every day was hard. When that ring was stolen, it was just another stab to the heart," said Purcell.Purcell shared the story on social media, explaining it was a devastating loss for him and his son."This was the one legacy item I wanted to pass on to him," said Purcell.Purcell's wallet was also stolen. The thieves used his credit card at the Walmart at 133rd and State Line; its surveillance video captured the alleged thieves’ faces.KCPD shared those images and together enough tips were gathered that detectives found the rings at a jewelry store in Raymore."They were honestly shocked," said Purcell.KCPD property crimes said it’s best to carefully photograph and document your items as extra insurance. Things like that can help them when trying to locate items. "The police never gave up," explained Purcell, who said he was incredibly grateful people stepped forward with information. "A few of them actually put their own personal risk on the line."The group Stolen KC promotes people speaking up about theft daily."We’ve had people identified within five or 10 minutes," explained Todd Howerton, who is on the Facebook group's administration team.Members post photos of missing items with the idea that someone knows something. The group would like to grow to a strength of 200,000. "The massive amount of people can facilitate finding things," said Howerton, who said they can take tips anonymously.That way, the things that are irreplaceable can be found."To have that, it gave me a lot of faith, a lot of hope, and a lot of thankfulness to people in the community who stepped up," said Purcell.Detectives told KSHB they are looking for three suspects in connection with the theft. They are wanted for possession of stolen property, burglary, and fraudulent use of credit. 2236
Just after Secretary of State Rex Tillerson's sudden firing Tuesday morning, American diplomats at posts spanning the globe were then increasingly surprised -- and in some cases disturbed -- to receive guidance from Washington telling them not to post or retweet the statement from Undersecretary of State Steve Goldstein on how Tillerson was fired by President Donald Trump, according to multiple diplomats who spoke to CNN about the guidance.Goldstein, part of Tillerson's tight inner circle of aides, had released a statement to the press and then tweeted words that he says came from Tillerson himself on his firing: "The secretary did not speak to the President this morning and is unaware of the reason, but he is grateful for the opportunity to serve, and still believes strongly that public service is a noble calling and not to be regretted." 859
JULIAN, Calif. (KGTV) - Headed to the snow this week? The San Diego County Sheriff’s Department wants to make sure you’re prepared for crowds.Snow fell in higher-elevations East County communities Wednesday, leading to the possibility of more families from low-lying areas traveling to the mountains.Deputies recommend you have a full tank of gas, water and food in case you’re stranded in traffic. Some areas may also require snow chains.CHECK WEATHER / CHECK TRAFFICAnyone who wants to play in the snow should respect private property fences and signs, deputies say.Parking in the mountains is limited. Violations will be enforced and citations issued by the Sheriff’s department. 695
JAMUL, Calif. (KGTV) - In Jamul, community members are banding together to help a family-owned farm decimated by the Valley Fire.Cheryl Skidmore, the owner of Hidden Haven Ranch, was on the phone with workers on site."Very, very smoky fire. Hit the ridge and then came down very fast," said Skidmore.Some animals were evacuated, but the damage was heavy at the 16-year-old farm known for sustainable farming.All 125 chickens were killed. Most of the crops were destroyed: half of the orchards, from apples to apricots, and all of the industrial hemp fields. The flames also burned a trailer and much of the farm equipment."Everything is just devastated. We have to start over," said Skidmore.Skidmore says she tried to get wildfire insurance but was denied, partly because she’s in a fire-prone area. The total loss was about 0,000. Shutting down the farm became very possible."It's overwhelming," said Skidmore.The word 'overwhelming' could also be used to describe the outpouring of support."The community has been donating hens. Hopefully, we will be doing egg production next month," said Skidmore.The farm asked for help and the community responded with dozens of volunteers at three cleanup efforts, including one on this day. Volunteers have done everything, from raking ash and trimming trees, to moving dirt and cleaning horse stalls. Jordyn Brewer is one of those volunteers."When I saw the pictures of the devastation, it made me upset. If I were in that situation, I would want people to help me," said Skidmore.Skidmore says that help will mean the difference between shutting down and keeping the farm going."No way I could have done this myself ... Just to see people so willing to help others, just makes me feel so good," said Skidmore.A lot of cleanup remains at the 52-acre farm. Skidmore says she’s planning at least seven more cleanups.A Gofundme campaign has been set up to help with the with the rebuild. 1938