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WASHINGTON, May 20 (Xinhua) -- Two U.S. astronauts conducted the first of four spacewalks for space shuttle Endeavour's STS-134 mission on Friday morning, the U.S. National Aeronautics and Space Administration (NASA) said.According to the U.S. space agency, Endeavour's mission specialists Andrew Feustel and Greg Chamitoff completed the six-hour, 19-minute spacewalk at 9:29 a.m. EDT (1329 GMT). They successfully installed antennas for the External Wireless Communication system, routing cables, setting up the antenna, installing handrails, and connecting power cables.Because of a carbon dioxide sensor failure in Chamitoff's spacesuit, flight controllers limited his spacewalk time to about six hours 20 minutes, 10 minutes less than the planned six hours and 30 minutes. There was no indication his suit's carbon dioxide levels would rise. However, they deferred tasks to remove a micrometeoroid debris shield to access and attach some of the connection points.This was the 245th spacewalk conducted by U.S. astronauts. It was Feustel's fourth spacewalk for a total time of 27 hours and 17 minutes, and Chamitoff's first.Endeavour lifted off on Monday morning from Kennedy Space Center in Florida, to deliver to the International Space Station a 2-billion-dollar, multinational particle detector known as the Alpha Magnetic Spectrometer (AMS).AMS, a particle physics detector, is designed to search for various types of unusual matter by measuring cosmic rays. Its experiments are designed to help researchers study the formation of the universe and search for evidence of dark matter, strange matter and antimatter.
WASHINGTON, April 6 (Xinhua) -- A study led by researchers at the University of Michigan (U-M) showed in animal studies that new cancer drug compounds they developed shrank tumors, with few side effects.The study, done in two mouse models of human cancer, looked at two compounds designed to activate a protein that kills cancer cells. The protein, p53, is inactivated in a significant number of human cancers. In some cases, it is because another protein, MDM2, binds to p53 and blocks its tumor suppresser function. This allows the tumor to grow unchecked. The new compounds block MDM2 from binding to p53, consequently activating p53."For the first time, we showed that activation of p53 by our highly potent and optimized MDM2 inhibitors can achieve complete tumor regression in a mouse model of human cancer," says lead study author Shaomeng Wang, director of the Cancer Drug Discovery Program at the U-M Comprehensive Cancer Center.Wang presented the study Wednesday at the American Association for Cancer Research 102nd annual meeting.Many traditional cancer drugs also activate p53 but they do so by causing DNA damage in both tumor cells and normal cells, causing side effects. These new MDM2 inhibitors activate p53 while avoiding the DNA damage common with other drugs. In this study, which was done in collaboration with Ascenta Therapeutics and Sanonfi-Aventis, researchers showed that these new drugs shrank tumors without significant side effects.Because p53 is involved in all types of human cancer, the new drug has potential to be used in multiple types of cancer. Further, the researchers also identified certain markers in tumors that predict which ones will be particularly sensitive to the MDM2 inhibitor, which would allow physicians to target the drug only to patients most likely to benefit.

SAN FRANCISCO, March 29 (Xinhua) -- Amazon.com Inc. on Tuesday announced the launch of an on-line music storage service,which enables users to store digital music in the cloud and access it from computers and devices running Google's Android operating system.The new service, called "Cloud Drive," offered customers five gigabytes of free storage on Amazon Web servers for all kinds of digital files, including music, photos, videos and documents. For paid plans, users can purchase storage space starting at 20 U.S. dollars a year for 20 gigabytes.The on-line retailer also launched "Cloud Player for Web" and " Cloud Player for Android." The former allows users to get the media files they stored on Amazon's servers from a Web browser on a Mac or PC. The latter lets users play music they have uploaded on Cloud Drive, computers or a smartphone that runs Android operating system.Analysts said Amazon is stepping up its rivalries with Apple and Google. Both companies are also working on similar services, allowing users to store their music on-line and access it from any compatible device.Media reports said that Apple was pushing hard to launch a digital music locker service in April. Google was also reported to be testing its own digital locker service but it still needs to make agreements with major music labels.
BEIJING, May 4 (Xinhuanet) -- Children with autism have slightly bigger brains than children without the condition, a study suggests.The research published in the May issue of Archives of General Psychiatry noted the difference in the brain size appears related to increased rates of brain growth before age 2.The researchers from the University of North Carolina also pointed out that though the enlargement continues, the increased growth does not.In 2005, the researchers studied a group of 2-year-old children, and found out the ones with autism had brains that were 5% to 10% larger than children without it.Now the researchers assessed the same group of children at age 5, the psychiatrists re-scanned the brains of 38 children with autism and 21 without the condition. The autistic children still had slightly larger brains, but they had grown at the same rate as the comparison group.This finding could lead to a better understanding of the genes that drive autism, which, in turn, could lead to earlier identification and treatment of the disorder, said study researcher Joseph Piven, MD, according to media report.
来源:资阳报