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CHARLOTTESVILLE, Va. - At the ripe age of 74, scientist Wladek Minor, PhD. is not slowing down anytime soon, especially when it comes to his research to better understand COVID-19.“This is the biggest danger I’ve seen in my lifetime,” said Minor. “This is a real danger, and we shouldn’t underestimate it.”Minor, who is also a professor at UVA’s Department of Molecular Physiology and Biological Physics, recently made a new discovery in the fight against coronavirus.As the lead researcher, Minor and his team of scientists recently discovered a link between a coronavirus treatment and people with diabetes.They found the drug dexamethasone, which is used to lower the risk of death in patients with a severe case of the virus, might be less effective for treating patients with diabetes.“We were trying to explain why the action of dexamethasone is somewhat erratic,” Minor said. “It means it works for some people and [does] not necessarily work for other people.”Minor and his team analyzed data from 373 COVID-19 patients at a hospital from Wuhan, China.Their research determined how a type of protein in our blood, called serum albumin, picks up dexamethasone and carries it through the body.The scientists found that patients who died had lower levels of that protein than those who survived.Those who died also had higher levels of blood sugar, suggesting diabetes may make it difficult for patients to get the benefits of the drug.“We are trying to make as much impact on human life as possible,” said Minor.Dexamethasone has been shown to cut deaths by about 30% for COVID-19 patients who were on ventilators.The steroid was used to help treat President Donald Trump’s bout with the virus, along with other treatments and drugs including remdesivir, which was just approved by the FDA to use on all hospitalized patients.“COVID is now our enemy, and really, it’s the biggest enemy,” Minor said.Scientists said more research is needed to determine the best treatment for COVID-19 patients, especially for those who have diabetes.For more information on Minor’s research, click here.This story was first reported by Antoinette DelBel at WTKR in Norfolk, Virginia. 2180

CAPE CANAVERAL, Fla. (AP) — The spacecraft team that brought us close-ups of Pluto will ring in the new year by exploring an even more distant and mysterious world.NASA's New Horizons spacecraft will zip past the scrawny, icy object nicknamed Ultima Thule (TOO-lee) soon after the stroke of midnight.One billion miles beyond Pluto and an astounding 4 billion miles from Earth (1.6 billion kilometers and 6.4 billion kilometers), Ultima Thule will be the farthest world ever explored by humankind. That's what makes this deep-freeze target so enticing; it's a preserved relic dating all the way back to our solar system's origin 4.5 billion years ago. No spacecraft has visited anything so primitive."What could be more exciting than that?" said project scientist Hal Weaver of Johns Hopkins University, part of the New Horizons team.Lead scientist Alan Stern of Southwest Research Institute in Boulder, Colorado, expects the New Year's encounter to be riskier and more difficult than the rendezvous with Pluto: The spacecraft is older, the target is smaller, the flyby is closer and the distance from us is greater.NEW HORIZONSNASA launched the spacecraft in 2006; it's about the size of a baby grand piano. It flew past Pluto in 2015, providing the first close-up views of the dwarf planet. With the wildly successful flyby behind them, mission planners won an extension from NASA and set their sights on a destination deep inside the Kuiper Belt. As distant as it is, Pluto is barely in the Kuiper Belt, the so-called Twilight Zone stretching beyond Neptune. Ultima Thule is in the Twilight Zone's heart.ULTIMA THULEThis Kuiper Belt object was discovered by the Hubble Space Telescope in 2014. Officially known as 2014 MU69, it got the nickname Ultima Thule in an online vote. In classic and medieval literature, Thule was the most distant, northernmost place beyond the known world. When New Horizons first glimpsed the rocky iceball in August it was just a dot. Good close-up pictures should be available the day after the flyby.ARE WE THERE YET?New Horizons will make its closest approach in the wee hours of Jan. 1 — 12:33 a.m. EST. The spacecraft will zoom within 2,200 miles (3,500 kilometers) of Ultima Thule, its seven science instruments going full blast. The coast should be clear: Scientists have yet to find any rings or moons around it that could batter the spacecraft. New Horizons hurtles through space at 31,500 mph (50,700 kph), and even something as minuscule as a grain of rice could demolish it. "There's some danger and some suspense," Stern said at a fall meeting of astronomers. It will take about 10 hours to get confirmation that the spacecraft completed — and survived — the encounter.POSSIBLY TWINSScientists speculate Ultima Thule could be two objects closely orbiting one another. If a solo act, it's likely 20 miles (32 kilometers) long at most. Envision a baked potato. "Cucumber, whatever. Pick your favorite vegetable," said astronomer Carey Lisse of Johns Hopkins. It could even be two bodies connected by a neck. If twins, each could be 9 miles to 12 miles (15 kilometers to 20 kilometers) in diameter.MAPPING MISSONScientists will map Ultima Thule every possible way. They anticipate impact craters, possibly also pits and sinkholes, but its surface also could prove to be smooth. As for color, Ultima Thule should be darker than coal, burned by eons of cosmic rays, with a reddish hue. Nothing is certain, though, including its orbit, so big that it takes almost 300 of our Earth years to circle the sun. Scientists say they know just enough about the orbit to intercept it.COMPARING FLYBYSNew Horizons will get considerably closer to Ultima Thule than it did to Pluto: 2,220 miles versus 7,770 miles (3,500 kilometers vs. 12,500 kilometers). At the same time, Ultima Thule is 100 times smaller than Pluto and therefore harder to track, making everything more challenging. It took 4 ? hours, each way, for flight controllers at Johns Hopkins' Applied Physics Lab in Laurel, Maryland, to get a message to or from New Horizons at Pluto. Compare that with more than six hours at Ultima Thule.WHAT'S NEXTIt will take almost two years for New Horizons to beam back all its data on Ultima Thule. A flyby of an even more distant world could be in the offing in the 2020s, if NASA approves another mission extension and the spacecraft remains healthy. At the very least, the nuclear-powered New Horizons will continue to observe objects from afar, as it pushes deeper into the Kuiper Belt. There are countless objects out there, waiting to be explored. 4591

CASTAIC (CNS) - A man who stole an SUV from a customer at a Santa Monica dealership led authorities on a chase for over two hours Friday, from South Los Angeles to Ventura County, before being arrested in the Castaic area.The man allegedly stole the Subaru from a person visiting a Santa Monica dealership "a few days ago," according to Sgt. Blake Cooper of the Santa Monica Police Department, but details were not immediately available.The chase started about 6:15 p.m. Friday, the Los Angeles Police Department said. It was not immediately clear where the chase began. The driver had a woman with him at the beginning of the pursuit, but she got out, according to broadcast reports. 692

CHICAGO, Ill. – The City of Chicago will soon implement under another stay-at-home advisory as it seeks to slow the spread of the coronavirus.The city’s mayor, Lori Lightfoot, announced Thursday that the advisory will go into effect on Monday, Nov. 16 at 6 a.m.Lightfoot says the advisory will call on the people of Chicago to stay at home unless for essential reasons, stop having guests over – including relatives they don’t live with, avoid non-essential travel, and cancel “traditional” Thanksgiving plans."Residents are advised to only leave home to go to work or school, or for essential needs such as seeking medical care, going to the grocery store or pharmacy, picking up food, or receiving deliveries," the city wrote.The city says the advisory will remain in place for 30 days or until the commissioner of health, Dr. Allison Arwady, determines a change in the guidance is appropriate.The new advisory comes as the city and many parts of the country experience the highest coronavirus case rates since the pandemic began. Lightfoot says data shows the city is seeing an average of at least 1,900 cases per day."If we continue on the path we’re on and don’t step up to do the things we know work, we estimate we will lose 1,000 more Chicagoans to this virus by the end of the year," said the mayor.Lightfoot says the stay-at-home advisory is part of a new strategy called “Protect Chicago,” which she describes as a comprehensive effort that includes new regulatory actions, neighborhood street-level activations and citywide public awareness.Watch the mayor's announcement below: 1598

California regulators want to tax text messages to increase funds for programs that bring connectivity to underserved residents.A new surcharge proposed by the California Public Utilities Commission (CPUC) wouldn't be a per-text tax, but a monthly fee based a cellular bill that includes any fees for text-message services. Most carriers offer a flat fee option for texting, and already charge a similar fee for other services included in the bill — such as phone calls. The exact structure of the charge would vary from carrier to carrier.The commission will vote on the measure January 10, 2019, and is facing strong opposition from industry trade groups like the CTIA, which represents AT&T Mobility, Sprint, and T-Mobile. (AT&T is the parent company of CNN.)The 52-page proposal by CPUC Commissioner Carla J. Peterman lays out the details of the plan, and says the state's Public Purpose Program budget is going up while incoming fees to fill it are decreasing. Currently the surcharge rate is less than 7%.The proposed plan could be complicated by a new Federal Communication Commission ruling. On Wednesday, the FCC approved a new rule that classifies text messages as an "information service" like email. Proponent of the rule say it will give carriers the ability to crack down on spam messages, and critics say it could lead to carriers censoring messages.The CTIA argued in a legal filing submitted Wednesday that if texts are an information service, then the CPUC doesn't have authority over them and can't add on surcharges. It claims the proposal would go against federal law.The industry group also says the proposal would create inequity "between wireless carriers and other providers of messaging services," such as WhatsApp, iMessage and Skype."Subjecting wireless carriers' text messaging traffic to surcharges that cannot be applied to the lion's share of messaging traffic and messaging providers is illogical, anticompetitive, and harmful to consumers," the CTIA said in its filing.In light of the FCC ruling and other legal filings submitted to the CPUC, the group could change its draft proposal before the vote next month.According to the CPUC, the charges go to a number of different programs, including 911 services, subsidized phone service for low-income residents, and equipment for deaf and hard-of-hearing users. 2379