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At least 18 people were killed -- most of them teenagers -- and about 50 more injured following an attack in Russian-annexed Crimea, according to Russia.Russia's National Anti-Terrorism Committee told CNN in a statement that a blast was caused by an "unidentified explosive device" at a college in the city of Kerch -- where a new 19-kilometer bridge links Crimea to Russia.Russia's Investigative Committee said in a statement: "According to preliminary data, an unidentified explosive device packed with metal objects went off today in the dining room of the Kerch Polytechnic College."It said information on the victims is being clarified and that "most of them are teenagers."Sergey Aksyonov, the head of the Crimean government, said the suspected perpetrator of the attack had taken his own life, according to remarks carried on Russian state television. 866

As states across the country grapple with an increase in coronavirus cases and a huge demand for tests, many businesses are looking for other ways to get more mileage out of their supply chain.Like with anything else, supply and demand is a constant struggle. In this unprecedented era, the demand for things like coronavirus tests is so large that public health departments don't have a choice but to figure out ways to make our supplies last. Several states are examining pooled testing. California's Public Health Department says it's to "better leverage testing resources."Pooling is something that blood banks have used for decades to keep their blood supply safe. Dr. Claudia Cohn is the Chief Medical Officer of the AABB, formerly known as the American Association of Blood Banks.“If you have 100 people that need to be tested and if you test each of them, you’ll do 100 tests. If you find that your test is sensitive enough that you can pool together 20 samples at the same time, instead of having 100 tests, you can have five pools of 20,” Dr. Cohn said.Now, if one of those five pools is positive, then Dr. Cohn says, "You’ll need to break it out and test each of those separately. So, let’s say you have one positive person in a pool of 100 people, you either do 100 tests and find one positive or you do five pools of 20, four of those pools will be negative, so you’ve done 4 pools and covered 80 people."The test works by taking a tiny sample from each person who was tested.“When you take a swab from everyone’s nose, you isolate the DNA from that swab,” Dr. Cohn said about the PCR test, which is generally a nose swab. “It’s not a lot, it’s a small amount but it’s enough. Because these tests are very, very sensitive.”Those tests are so sensitive, and they have to be, that pooling can really only work if the test can handle, as in detect, multiple samples at once. The FDA mandates that.“The FDA is quite demanding as they should be in terms of making sure tests work well and are safe,” Dr. Cohn said.And Dr. Cohn says, pooling wouldn't work in an area where there's a large outbreak, which means a large number of people would test positive regardless of pooling. In the blood world, this strategy has been perfected.“You are taking 100 samples and taking a drop from each sample and putting it together,” Dr. Cohn said. “You are testing every single person who comes through. In the blood world safety is before everything."Blood banks test for HIV, Hepatitis C and B and well as COVID-19 antibodies, according to the American Red Cross. And, as this pandemic moves through our communities, Dr. Cohn says our blood supply needs to remain strong.“After that initial spike, it went down again and that was okay because elective surgery had been canceled, so the demand for blood had gone down as well so for a while we were at a good balance of demand and supply. But then elective surgeries opened up and hospitals went back to full service and we’re in a shortage again,” Dr. Cohn said. 3017

At least one airline is starting to pull back on their cleaning regimen. Southwest crews are limiting their between-flight cleanings and leaving most of the passenger areas for the overnight cleaning crew, according to reports.Following the coronavirus outbreak in March and subsequent travel bans, airlines touted their stepped-up cleaning protocols as passengers returned.Starting in August, Southwest is focusing on lavatories and tray tables between flights, leaving seat belts, arm rests and other areas for the overnight cleaning crew, Southwest representative Ro Hawthorne told the Dallas Morning News."Since flight schedules have increased, other areas of the aircraft will be disinfected during our overnight cleaning process, when Southwest Teams spend six to seven hours per aircraft cleaning all interior surfaces," Hawthorne said in a statement.“As always, Southwest will monitor customer and employee feedback as we adapt to the new normal in air travel, while ensuring we keep safety as our top priority,” the statement continued.In March, Southwest announced their cleaning program included "interior windows and shades, every seat belt buckle, passenger service units (including the touch buttons that control reading lights and vents that direct personal air), as well as seat surfaces, tray tables, armrests, etc."The change to cleaning protocol will reduce the time an aircraft spends on the ground between flights, the airline told flight attendants in a memo obtained by CNN. 1505

As we drive down the eerily deserted Hong Kong-Zhuhai-Macau Bridge, the murky waters of the Pearl River Delta stretch as far as the eye can see. There is no land in sight.Spanning 34 miles (55 kilometers), this is the longest sea-crossing bridge ever built. Guo Xinglin, assistant director and senior engineer at the Hong Kong-Zhuhai-Macao Bridge Authority, meets us half way along. As we are buffeted by a strong wind, the tough conditions his construction crew experienced, as they perched on precarious platforms, working miles from land and high over the water, are evident.Guo is visibly proud of his country's monumental achievement. 647

Back by popular demand, Applebee's is once again offering cheap drinks all month long.The company is offering margaritas for the entire month of April. They originally ran this promotion in October but brought it back.There isn't even a time limit on the drinks. They're available from open to close at every location."It's seriously just - 100 pennies, that's all," the company said in a release."go ahead, put that dollar burning a hole in your pocket to good use and buy yourself something delicious." 518