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TAMPA, Fla. — A 0,000 reward is being offered for information on the 1997 disappearance of Don Lewis, the Tampa man whose case was featured in Netflix's "Tiger King."Lewis' family held a press conference Monday morning at Riverhills Church of God in Tampa.“Amazingly, our little family tragedy has become your tragedy. Our search for closure and truth has become your mission also,” said Lewis’ daughter, Gale Rathbone.The family has retained Jacksonville attorney John Phillips to conduct their own independent investigation into the circumstances surrounding the disappearance.Phillips says he will represent anyone willing to come forward with information pro-bono.RELATED: Hillsborough sheriff asks for new leads for missing man featured in Netflix's 'Tiger King'Lewis was reported missing in 1997 by his wife, Carole Baskin.In the wake of Lewis' disappearance, viewers of the Netflix series have shared theories about what happened.“Think about your grandfather being rumored to either have been eaten by alligators, be under a septic tank of feces or in a meat grinder,” said Phillips.But as wild as it may sound, Phillips says there may be merit to those theories.Baskin, the owner of Tampa's Big Cat Rescue, was featured in the Netflix hit series, which briefly touched on Lewis' disappearance.Since the show's release, Baskin and her current husband, Howard, said producers duped them into thinking the series would be about stopping the abuse of big cats."Anyone who spends an hour with Carole would come away knowing that there was no way that she had any involvement in Don's disappearance and that the vicious rumors that were spread by his family are absolute nonsense stuff about meat grinders and septic tanks," said Howard Baskin.There have been renewed calls from authorities for tips in Lewis' case since the show was released. An anonymous donor helped the family raise the reward to 0,000,“Whomever that person is, we are so grateful. We are hoping that with those funds someone will have the courage to come forward,” said daughter Donna Pettis. 2081

The Barron County Sheriff said the possible sighting of a missing and endangered Wisconsin teen in Miami, Florida doesn't appear to be credible. An AMBER Alert was issued Monday afternoon for 13-year-old Jayme Closs after her parents were found dead in their home. Gas station surveillance video from Miami shows the girl a witness thought to be Jayme. The FBI has yet to confirm it was. Barron County Sheriff Chris Fitzgerald indicated Tuesday it isn't credible. A witness claims to have seen Jayme inside this black SUV with Wisconsin plates Monday afternoon at a Miami gas station. That's 1,700 miles away from where Jayme's last confirmed sighting Sunday afternoon in her hometown. Surveillance video briefly shows a teenage girl sitting in the front passenger seat as the driver pulled up to a gas pump. She doesn't appear to be restrained at the time. Moments before, a man got out of that same vehicle and walked up to another SUV and a truck to talk with others. Miami police shared the possible sighting via social media on Monday night. "We are actively researching that tip," said Fitzgerald. Fitzgerald appeared frustrated at news conference Tuesday that Miami police released information about a possible tip. "Every tip continues to be followed up on and if it's something we need to get out to you, you will get that information and it will come directly from me out to you," Fitzgerald said. Authorities were first alerted to Jayme's disappearance early Monday morning when a 911 call led sheriff's deputies to her home in Barron. Jayme's parents were found shot to death. Fitzgerald is asking Barron County residents to keep an eye out for others acting out of character. He said they've questioned a lot of people while following up on tips, however Jayme is still believed to be missing and in danger. 1883

Sticking to a normal daily rhythm -- being active during the day and sleeping at night -- can have more benefits than you might expect.A new study found that it is linked to improvements in mood and cognitive functioning as well as a decreased likelihood of developing major depression and bipolar disorder.The study, published Tuesday in the journal The Lancet Psychiatry, looked at disruptions in the circadian rhythms -- or daily sleep-wake cycles -- of over 91,000 adults in the United Kingdom. It measured these disruptions using a device called an accelerometer that is worn on the wrist and measures one's daily activity levels. The participants were taken from the UK Biobank, a large cohort of over half a million UK adults ages 37 to 73.The researchers found that individuals with more circadian rhythm disruptions -- defined as increased activity at night, decreased activity during the day or both -- were significantly more likely to have symptoms consistent with bipolar disorder or major depression. They were also more likely to have decreased feelings of well-being and to have reduced cognitive functioning, based on a computer-generated reaction time test.For all participants, activity levels were measured over a seven-day period in either 2013 or 2014, and mental health proxies such as mood and cognitive functioning were measured using an online mental health questionnaire that participants filled out in 2016 or 2017."It's widely known that a good night's sleep is a good thing for well-being and health. That's not a big surprise," said?Dr. Daniel Smith, professor of psychiatry at the University of Glasgow and a leading author on the study. "But I think what's less well-known and what comes out of this work is that not only is a good night's sleep important, but having a regular rhythm of being active in daylight and inactive in darkness over time is important for mental well-being."The findings were found to be consistent even when controlling for a number of influential factors including age, sex, lifestyle, education and body mass index, according to Smith."I think one of the striking things that we found was just the consistency in the direction of our association across everything we looked at in terms of mental health," Smith said.Daily circadian rhythm is controlled by a collection of neurons in an area of the brain called the hypothalamus. The hypothalamus helps regulate a number of important behavioral and physiological functions such as body temperature, eating and drinking habits, emotional well-being and sleep, according to the?National Institute of General Medical Sciences.The findings are consistent with research indicating a link between sleep disruptions and mood disorders. A 2009 study, for example, showed that men who worked night shifts for four years or more were more likely to have anxiety and depression than those who work during the day.However, the new study is the first to use objective measurements of daily activity and is among the largest of its kind, according to?Aiden Doherty, senior research fellow at the University of Oxford, who was not involved in the research."This study is the first large-scale investigation of the association of objectively measured circadian rhythmicity with various mental health, well-being, personality and cognitive outcomes, with an unprecedented sample size of more than 90 000 participants," Doherty wrote in an email."Previous studies have been very small (in just a few hundred people), or relied on self-report measures (asking people what they think they do). ... However, this study used objective device-based measures in over 90,000 participants; and then linked this information to standard measures of mood disorders, subjective well-being, and cognitive function," he added.The findings have significant public health consequences, particularly for those who live in urban areas, where circadian rhythms are often disrupted due to artificial light, according to Smith."By 2030, two-thirds of the world's population will be living in cities, and we know that living in an urban environment can be pretty toxic to your circadian system because of all the artificial light that you're exposed to," Smith said."So we need to think about ways to help people tune in to their natural rhythms of activity and sleeping more effectively. Hopefully, that will protect a lot of people from mood disorders."For those who struggle to maintain a consistent circadian rhythm, certain strategies -- such as avoiding technology at night -- have proven to be an important part of good sleep hygiene."Not using your phone late at night and having a regular pattern of sleeping is really important," Smith said. "But equally important is a pattern of exposing yourself to sunshine and daylight in the morning and doing activity in the morning or midday so you can actually sleep properly."Based on the observational nature of the study, the researchers were unable to show causality, meaning it is unclear whether the sleep disturbances caused the mental health problems or vice versa."It's a cross-sectional study, so we can't say anything about cause and effect or what came first, the mood disorder or the circadian disruption," said Kristen Knutson, associate professor of neurology at Northwestern's Feinberg School of Medicine, who was not involved in the study."And it's likely they affect each other in a circular fashion," she added.The researchers also looked exclusively at adults between age 37 and 73, meaning the results may not apply to younger individuals, whose circadian rhythms are known to be different than those of older adults, according to Smith."The circadian system changes throughout life. If you've got kids, you know that very young kids tend to be nocturnal," Smith said. "My suspicion is that we might observe even more pronounced effects in younger samples, but that hasn't been done yet, to my knowledge."But the study adds more credence to the idea that sleep hygiene -- including maintaining a consistent pattern of sleep and wake cycles -- may be an important component of good mental health, according to Smith."It's an exciting time for this kind of research because it's beginning to have some real-world applications," Smith said. "And from my point of view as a psychiatrist, I think it's probably under-recognized in psychiatry how important healthy circadian function is, but it's an area that we're trying to develop." 6496

Terminally ill British toddler Alfie Evans died overnight, days after life support was withdrawn, according to messages posted by his parents on Facebook on Saturday."My gladiator lay down his shield and gained his wings at 02:30. absolutely heartbroken. I LOVE YOU MY GUY," his father, Thomas Evans, wrote on the "Save Alfie Evans" Facebook page."Our baby boy grew his wings tonight at 2:30 am. We are heart broken. Thankyou everyone for all your support," his mother, Kate James, posted on the "Alfies Army Official" Facebook page.The 23-month-old boy, who had a degenerative brain condition, had been at the center of a high profile legal battle over whether life support should be continued. The case has stirred strong emotions both in Britain and abroad, with hundreds of thousands signing petitions supporting him.Alfie, who was admitted to Alder Hey Hospital in December 2016, was diagnosed with a neurodegenerative disease associated with severe epilepsy and had been in a semivegetative state for more than a year. During that time, he was kept alive by artificial ventilation in the critical care unit. 1121

Stephen Hawking, the brilliant British theoretical physicist who overcame a debilitating disease to publish wildly popular books probing the mysteries of the universe, has died, according to a family spokesman. He was 76.Considered by many to be the world's greatest living scientist, Hawking was also a cosmologist, astronomer, mathematician and author of numerous books including the landmark "A Brief History of Time," which has sold more than 10 million copies.Celebrity deaths of 2018: Remembering those we've lost this yearWith fellow physicist Roger Penrose, Hawking merged Einstein's theory of relativity with quantum theory to suggest that space and time would begin with the Big Bang and end in black holes. Hawking also discovered that black holes were not completely black but emit radiation and would likely eventually evaporate and disappear."A star just went out in the cosmos," Lawrence Krauss, a theoretical physicist and cosmologist, wrote on Twitter. "We have lost an amazing human being."Hawking suffered from ALS (amyotrophic lateral sclerosis), a neurodegenerative disease commonly known as Lou Gehrig's Disease, which is usually fatal within a few years. He was diagnosed in 1963, when he was 21, and doctors initially only gave him a few years to live.The disease left Hawking wheelchair-bound and paralyzed. He was able to move only a few fingers on one hand and was completely dependent on others or on technology for virtually everything -- bathing, dressing, eating, even speech.Hawking used a speech synthesizer that allowed him to speak in a computerized voice with an American accent."I try to lead as normal a life as possible, and not think about my condition, or regret the things it prevents me from doing, which are not that many," he wrote on his website."I have been lucky that my condition has progressed more slowly than is often the case. But it shows that one need not lose hope."Hawking was married twice. He and his first wife, Jane Wilde, wed when he was still a grad student and remained together for 30 years before divorcing in 1995. Hawking was later married for 11 years to Elaine Mason, one of his former nurses.Hawking was born in Oxford, England, on what turned out to be an auspicious date: January 8, 1942 -- the 300th anniversary of the death of astronomer and physicist Galileo Galilei.In an exclusive interview with CNN in October 2008, Hawking said that if humans can survive the next 200 years and learn to live in space, then our future will be bright."I believe that the long-term future of the human race must be in space," Hawking told CNN's Becky Anderson."It will be difficult enough to avoid disaster on planet Earth in the next 100 years, let alone next thousand, or million. The human race shouldn't have all its eggs in one basket, or on one planet. Let's hope we can avoid dropping the basket until we have spread the load."At Cambridge, he held the position of Lucasian Professor of Mathematics -- the prestigious post held from 1669 to 1702 by Sir Isaac Newton, widely considered one of the greatest scientists in modern history.Yet Hawking once said if he had the chance to meet Newton or Marilyn Monroe, he would opt for the movie star.Hawking became a hero to math and science geeks and pop culture figure, guest-starring as himself on "Star Trek: The Next Generation" and "The Simpsons." His life was dramatized in the 2014 movie, "The Theory of Everything."He had at least 12 honorary degrees and was awarded the CBE in 1982. A CBE, or Commander in the Most Excellent Order of the British Empire, is considered a major honor for a British citizen and is one rank below knighthood.Despite being a British citizen he was awarded the Presidential Medal of Freedom, the US's highest civilian honor, in 2009 by President Barack Obama.In September 2016 Hawking joined 375 "concerned" scientists in penning an open letter criticizing then-presidential candidate Donald Trump, citing the threat of climate change and blasting his push for the US to leave the Paris Accord.Fellow scientists hailed Hawking for his work and influence in the field."His passing has left an intellectual vacuum in his wake," tweeted Neil deGrasse Tyson. "But it's not empty. Think of it as a kind of vacuum energy permeating the fabric of spacetime that defies measure."Hawking leaves behind three children and three grandchildren. "We are deeply saddened that our beloved father passed away today," Hawking's children, Lucy, Robert and Tim, said in a statement. "He was a great scientist and an extraordinary man whose work and legacy will live on for many years. His courage and persistence with his brilliance and humor inspired people across the world.""He once said, 'It would not be much of a universe if it wasn't home to the people you love.' We will miss him forever."The-CNN-Wire 4846