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The CDC has recently issued guidance indicating that up to nearly one half of antibody tests are inaccurate.While early indications are that having antibodies offers some protection against reinfection, the CDC said too little is known about antibodies to determine whether it is safe for a person to no longer need to conduct social distancing. Additionally, the CDC said that a positive test should not be used at this time to determine if an individual is immune.The CDC added, “Serologic test results should not be used to make decisions about grouping persons residing in or being admitted to congregate settings, such as schools, dormitories, or correctional facilities.”The CDC said that it recommends providers use multiple antibody tests on patients, and it obtains the most accurate tests available.The CDC said that the prevalence of those testing positive for antibodies among the general population is between 5 and 25, with higher figures coming from areas with localized outbreaks. The FDA has also warned that all antibody tests can produce false results, and that “broad use of the tests, when not appropriately informed by other relevant information, such as clinical history or diagnostic test results, could identify too many false-positive individuals.” 1286

The 2019 Nobel Prize for Medicine has been jointly awarded to William Kaelin Jr., Sir Peter Ratcliffe and Gregg Semenza for their pioneering research into how human cells respond to changing oxygen levels.Announcing the prize at the Karolinska Institute in Stockholm on Monday, the Nobel committee said that the trio's discoveries have paved the way for "promising new strategies to fight anaemia, cancer and many other diseases."The 2019 medicine laureates, the committee added, have identified molecular machinery that regulates the activity of genes in response to varying levels of oxygen.The importance of oxygen has long been established, the committee explained, but how cells adapt to changes in its levels remained unknown.Randall Johnson, prize committee member, described the trio's work as a "textbook discovery.""This is something basic biology students will be learning about when they study, at aged 12 or 13, or younger, biology and learn the fundamental ways cells work. This is a basic aspect of how a cell works and, from that standpoint alone, it's a very exciting thing."The winnersNew York-born Kaelin established his own research laboratory at the Dana-Farber Cancer Institute in Boston and became a full professor at Harvard Medical School in 2002.Semenza, also born in New York, became a full-time professor at Johns Hopkins University in 1999 and since 2003 has been the Director of the Vascular Research Program at the Johns Hopkins Institute for Cell Engineering.Ratcliffe, who was born in Lancashire, England, studied medicine at Cambridge University and established an independent research group at Oxford University, becoming a full professor in 1996. 1694

The Dominican Republic's top tourism official on Friday downplayed a spate of deaths among American tourists as an exaggeration."It's not true that there has been an avalanche of American tourists dying in our country, and it's not true that we have mysterious deaths here," Tourism Minister Francisco Javier Garcia told reporters.Garcia said toxicology reports were still pending in some cases but that autopsy results and causes of death have been released. He said his country has been in constant communication with US Embassy officials.The characterization in some media outlets of an "avalanche of deaths does not correspond to reality," he said.At the news conference, the minister read the names of the Americans who have died in the past year, with the official cause of death -- noting that all died of natural causes.Garcia said Americans are not canceling their vacations to the Dominican Republic. His country was working to clear up what he called misrepresentations and "exaggerated" reports about the deaths."We want the truth, not a special treatment," he said.At least nine American citizens have died at Dominican Republic resorts -- or after falling ill at one -- over the past year, according to information from the US State Department, victims' family members and the resorts involved.The deaths have left some Americans wondering if they should cancel upcoming trips to the Caribbean nation.Officials there have called the deaths isolated events as they work to reassure travelers their country is safe.Of the nine Americans who have died while or after visiting a Dominican Republic resort since June 2018, it's not clear how many deaths owed to natural causes.Samples taken from at least one minibar at the Bahia Principe Hotel were being tested by the FBI as part of the agency's collaboration with Dominican authorities, the country's public health ministry said this week.Officials in the Dominican Republican or the United States have not said the deaths are connected.Three of the Americans died at the Bahia Principe resort in La Romana within days of each other. Two died at the Hard Rock Hotel & Casino in Punta Cana.The investigations into the deaths have included visits from health inspectors, including environmental health and epidemiology specialists, according to Carlos Suero, spokesman for the public health ministry.The State Department has a standing travel advisory for the Dominican Republic, urging travelers to have caution because of crime, but it has not issued a travel alert specific to the traveler deaths.From 2012 to 2018, 128 Americans died in the Dominican Republic from something other than natural causes, according to US State Department statistics. That averages about 18 annually.The Dominican Republic is one of the Caribbean's top tourism destinations, with more than 6 million stopover tourists last year, including 2.2 million Americans, according to the Caribbean Tourism Organization.Tourism represented more than 17 percent of the country's economy last year, according to the World Travel & Tourism Council. 3098

The number of children and teens in the United States who visited emergency rooms for suicidal thoughts and suicide attempts doubled between 2007 and 2015, according to a new analysis.Researchers used publicly available data from the 246

The National Rifle Association is suing after the San Francisco Board of Supervisors labeled it a "domestic terrorist organization," according to the complaint.Last week, the board 193