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JUPITER, Fla. — Groundbreaking research out of the Scripps Research Institute in Jupiter, Florida found a genetic explanation for the pain processing and sensory issues some children living with autism face."To see the biology in the lab turn out that has parallels to what’s going on in these children takes it so far beyond just an academic endeavor," said Dr. Gavin Rumbaugh, a neuroscientist at Scripps. "You go home every day thinking, unbelievably, I may actually be making a difference in someone's life."One of those children who Rumbaugh hopes to help with his research is 10-year-old Beckett, who lives in Texas."We wanted to understand generally in the lab how genes like SYNGAP1 affect the way the brain functions and we thought what better way was then to look and see how this gene may directly affect sensory processing, and then further on ask the question, 'Does the change in sensory processing actually lead directly to learning, memory and behavioral impairment?' " he said.Beckett has a genetic mutation of SYNGAP1, which researchers have now found causes certain issues he faces, particularly, having an extremely high pain threshold while also experiencing heightened sensitivity to another kind of stimuli. Beckett and other children living with this genetic mutation also often have epilepsy."It's all about quality of life. Everybody deserves to live their best life and that's my mission," said Monica Weldon, Beckett's mom.Weldon said the research being done in Jupiter could change her son's life and the lives of hundreds of other children around the world with the same genetic abnormality and symptoms, some of whom whose families she's connected with online."That is the power I believe of a patient group that is motivated to find treatments for their loved ones," Weldon said. "Also, you've got scientists who are listening. They're willing to listen and they're willing to learn."The next step in Rumbaugh's research is to look at treating the symptoms from the genetic mutation. 2043

KANSAS CITY, Mo. — A former U.S. Secret Service agent who worked on a presidential detail for the late George H.W. Bush reminisced about the 41st president of the United States on Saturday after learning of Bush's passing.Mauri Sheer spent two years with the Bush family during his presidency before he was appointed as a U.S. Marshal in the Kansas City area. Sheer, who worked in the Secret Service for nearly three decades, served six presidents."From Gerald Ford through George W. Bush," Sheer said.But it was his time with George H.W. Bush, who died Friday night at his home in Texas, that he thought about most this weekend."He was constantly moving, and when he would move, he would move fast," Sheer said. "If you were working right ahead of him in the perimeter around him and you were right ahead of him, you'd have to be careful if you slowed down because he'd run you right over."Sheer said that same energy went into his golf game. "They say he played golf almost like you play hockey," Sheer said. "He'd hit the ball and the ball's almost done moving and he's just constantly moving."Sheer said the moment he'd never forget was the day Ronald Reagan was released from the hospital after he'd been shot. Sheer said he and Bush were running a 10-kilometer race that morning. "He didn't run as fast as he thought he was going to and he was pressed for time and he was behind and he was afraid he was going to miss it," Sheer said.As usual, Bush didn't miss a beat.Sheer said that's one thing he'll always remember. He also wanted others to know Bush was a fundamentally good person."The main thing that I think people should know about George H.W. Bush is that he's one of the most decent guys I'd ever been around," Sheer said.He also will remember Bush as a generous man who cared deeply about others.During the holiday season, Sheer said Bush would plan his schedule around his agents, so they could be home with their families for the holidays. 2001

James Harvey has owned a moving company for the past 10 years.He says every summer it’s the same: he sees a spike in business with more people moving. This summer, however, is different he’s says because of COVID-19.“It’s an emotional time,” said Harvey, owner of Around the Clock Movers and Havana Truck Rentals. “It’s hard not to feel bad for a lot of people.”Paperwork is piling up as Harvey tries to meet the demand for his customers that often tell him their reasons for relocating.“Before people were moving for fun or moving to experience new things,” he said. “Now it’s for economics.”What Harvey is experiencing is happening across the country.A new study by the Pew Research Center shows one in every five American adults moved due to COVID-19 or know someone who did.“Everything going on is highly emotional right now,” said real estate expert Lauren Feldesman with Compass.Feldesman has helped many people move out of the early epicenter of this pandemic -- New York City.With more people escaping big city living during this crisis, Feldesman says just looking at properties now is a lot more involved. She added there’s also a lot less tolerance for any potential health risks.“Even just today I had somebody that had to cancel the showing because they said that they just flew here two days ago from a high-risk state,” she said. “I was like, ‘I’m sorry. I can’t show you the property.’”These moves are impacting more than just those moving.With so many Americans changing their address, it’s changing property prices across the country, some at historic rates, according to real estate tracker Zumper.There’s a lot of good people that don’t deserve to be going through these situationsWhile Harvey has mixed emotions about helping people move to help reduce their risk of contracting the virus he also understands the importance of moving out and moving on. 1881

JAPATUL VALLEY (CNS) - A fire that has blackened 17,665 acres in rural eastern San Diego County remains at 87% containment Sunday, authorities said."Fire activity was minimal overnight as firefighters continue to mop up hot spots and secure the fire perimeter," according to a U.S. Forest Service news statement. "Structure defense remains a priority for values at risk. Every day the fire stays within its current perimeter, the threat to the adjacent communities continues to diminish. High pressure over Southern California will result in a warming trend into the middle of the week."The Valley fire, southeast of Alpine, has destroyed 30 residences and 31 outbuildings, damaged 11 other structures and injured three firefighters.RELATED: Resource event gets Valley Fire victims back on their feetFire activity was limited Saturday as firefighters continued to mop up hot spots and secure the fire perimeter, officials said. A high-pressure system was expected to keep temperatures high through the rest of the weekend.At noon Friday, Cal Fire announced that all evacuations and road closures necessitated by the conflagration, dubbed the Valley Fire, had been lifted.Saturday morning, the county announced the reopening of the Lake Morena and Potrero campgrounds that had been closed during the evacuation orders. Campsites were available to book at http://reservations.sdparks.org.However, the Cleveland National Forest remained closed to the public until further notice "to protect natural resources and provide for the safety of the public and firefighters," Cal Fire advised.RELATED: Valley Fire claims Jamul woman's home, beloved animals"This closure will stay in place until conditions improve and we are confident that national forest visitors can recreate safely," officials with the state agency said.The blaze erupted for unknown reasons early Sept. 5 off Spirit Trail and Carveacre Road and spread rapidly through tinder-dry vegetation amid sweltering heat and high winds, Cal Fire officials said.The agency cautioned those returning to the fire-ravaged area to "use extreme caution around trees, power poles and other tall objects or structures that may have been weakened" by the blaze.The San Diego County Sheriff's Department was increasing its patrols in the area to ensure public safety and prevent looting.Officials advised that motorists in the area could face traffic disruptions due to the continued presence of firefighters, law enforcement personnel and utility workers still in the area.Non-residents were asked to avoid locales in and around the burn zone if possible.About 140 San Diego Gas & Electric customers in Alpine, Barrett Lake, Dehesa, Lyons Valley and Rancho Palo Verde lost power during the fire fight.Due to smoke drifting over much of the San Diego region, the county Pollution Control District advised that the air quality might be unhealthy in some local communities and advised people to limit outdoor activities until conditions improve.Gov. Gavin Newsom declared a state of emergency for San Diego County on Sunday Sept. 6 due to the Valley Fire, a move intended to free up federal relief funds.County officials encouraged people who have lost their homes or other property to the wildfire to call for assistance at 858-715-2200 or email valleyfirerecovery.@sdcounty@ca.gov.Additionally, a county assistance center for victims of the blaze will be in operation at Rancho San Diego Library, 11555 Via Rancho San Diego, on Saturdays and Sundays from 10 a.m. to 6 p.m. and Mondays from 11 a.m. to 7 p.m. until further notice.Those who would like to help victims of the fire can make donations to a disaster-relief fund implemented by the San Diego Foundation, which can be accessed online at sdcountyrecovery.com. 3770

John Lennon and lemonade do not mix.Yoko Ono has intervened to stop the sale of "John Lemon" lemonade in Europe, accusing the brand of profiting from the memory of her late husband.Ono, who married the Beatles star in 1969, filed suit against the Polish "John Lemon" startup in April at a court in the Hague. 316