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GAITHERSBURG, Md. -- Under the fluorescent lights, inside a series of labs, researchers believe they may have cracked the code to create a vaccine for the new coronavirus, which has officially named COVID-19.“It’s rapidly evolving,” said Dr. Gregory Glenn, president of research and development at the Maryland-based company Novavax. “As a company, we are very invested in looking at how to protect people against infectious diseases.”Novavax is one of several pharmaceutical companies around the world, racing to develop a vaccine for the strain of the coronavirus, which recently emerged in Wuhan, China.“We have to puzzle-solve with vaccines,” Dr. Glenn said. “We think about: what do we want to have the immune response to target? Because that should block the infection and stop the illness and that’s the goal here.”He showed a three-dimensional computerized depiction of what the virus looks like.“The coronavirus – corona being ‘crown’ – has spikes,” he said. “Those spikes have a very important function. They let the virus bind to the human cell and then those spikes act as a syringe to inject genetic material into the human cell.”A vaccine would potentially stop that process, thereby protecting a person from the coronavirus.“We have the gene, we have the vaccine, we’re going to move it into animal testing shortly,” Dr. Glenn said. “Our goal is in late spring to be testing in humans.”It normally takes about 18 months to get human trials started on a vaccine. This shorter time frame is nothing new for the company; they developed an Ebola vaccine within 90 days ready for testing – but there’s a catch.It can take years for a vaccine to get approved, but under dire circumstances sometimes they can be used through something called “expanded access” or “compassionate use” – meaning, the vaccine can be used in humans, before it’s fully licensed.“That happened with Ebola – they didn’t have a licensed vaccine, but they were able to use it under ‘compassionate use,’ they developed evidence that it was working,” Dr. Glenn said.As for a fully approved coronavirus vaccine, experts say that would take longer.“A vaccine in a year would be record-setting time, but not in time to probably have much impact for this disease outbreak,” said Dr. Eric Toner with the Johns Hopkins Center for Health Security.However, if the coronavirus sticks around or comes back stronger in a second wave of the disease, Dr. Glenn said they want to be ready.“We know time is of the essence here,” he said.So far, approximately 73,000 people have been infected and more than 1,800 people have died from the most recent strain of the coronavirus. 2653
Former MLB player Bill Buckner, a former first baseman best known for a crucial error in the 1986 World Series, has died according to 146
Flash flooding was prompting rescues from homes and cars Thursday morning in the Philadelphia area, including southern New Jersey, where high water also closed parts of Interstate 295 for hours.The flooding is part of the same system that 251
HOUSTON — Country/rap singer Justin Carter has died after an accidental shooting that occurred while he was filming a music video.The Texas-based singer was shot and killed at his apartment in Houston, a 216
For the second time in less than six months, a brand-new Boeing aircraft has crashed just minutes into a flight.All 157 people on board the Ethiopian Airlines flight from Addis Ababa that crashed on Sunday morning have died, the airline has confirmed.The tragedy follows the Lion Air flight that went down over the Java Sea in late October, killing all 189 people on board.There is no suggestion yet as to what caused the latest disaster, and no evidence that the two incidents are linked in causality.What is known, however, is that both flights took place on the Boeing 737 MAX 8 -- a new model recently unveiled to great fanfare by the US aviation giant, that saw its first flight less than two years ago."It's highly suspicious," said Mary Schiavo, a CNN aviation analyst and the former Inspector General of the U.S. Transportation Department. "Here we have a brand-new aircraft that's gone down twice in a year. That rings alarm bells in the aviation industry, because that just doesn't happen."Adding to concerns are some similarities between the two flights. Both were operated by well-known airlines with strong safety records -- but the Lion Air flight went down 13 minutes after take off, while Sunday's Ethiopian Airlines flight crashed just six minutes into its journey.And while the Ethiopian Airlines did not see the wild fluctuations in altitude that the Lion Air flight saw, it did dip and then regain altitude before it crashed."The similarities with Lion Air are too great not to be concerned," Schiavo said.Data from flight recorders awaitedAt the root of October's Lion Air crash was a new safety system installed in the MAX 8 plane, known as the Maneuvering Characteristics Augmentation System (MCAS), that automatically pulls the plane's nose down if data suggests it is at risk.In that flight, the system was responding to faulty data that suggested the nose was tilted at a higher angle than it was, indicating the plane was at risk of stalling.The pilots subsequently engaged in a futile tug-of-war with the plane's automatic systems, trying to reverse a nosedive that should not be triggered so soon after takeoff. Boeing has argued that pilots should have identified the system was in operation, and turned it off."All pilots should have been trained on that function after Lion Air," Schiavo added. "Boeing did something very unusual for any manufacturer -- it sent out an emergency bulletin and told all airlines to make sure they trained the pilots in the shut-off procedure.""This is one of the things that should never be happening after takeoff," Schiavo said.It is too early for conclusions to be drawn as to whether the same issue occurred on the Ethiopian Airlines flight -- but a clue could come sooner rather than later."We will not get a final determination for two or three years, but we will get information from the flight recorders -- which I'm guessing will be fairly easy to retrieve -- in a matter of weeks," said CNN anchor Richard Quest, who specializes in aviation."At the moment, it seems a coincidence" that both disasters occurred on the same aircraft, Quest said. "But I'm guaranteeing to you that the authorities will be examining just how close a coincidence, and whether there are common circumstances between the two," he said."Two brand new planes have crashed from two respected airlines," Quest added. "Ethiopian is a very, very well-run airline. There is no safety issue on Ethiopian Airlines."Possible repercussions for Boeing If investigators do uncover a similar cause of the two accidents, the repercussions for Boeing could be dramatic."The Lion Air flight was a big deal for Boeing, but they managed to overcome it," Schiavo says. "They put out the emergency warning about training, and the industry went on. With the second one, I don't think everybody's going to forget."The MAX 8 could be grounded if a link is found -- either by the company itself, or by governments, though the former is more likely to come first, Schiavo says. "The voluntary basis is always the better way to go -- but it will be expensive for Boeing."Airlines with MAX 8 aircraft in their fleet -- and those with outstanding MAX 8 orders -- are likely to be watching developments closely in the coming days and weeks.According to 4284