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As the COVID-19 pandemic progresses, researchers say it is important to track how the coronavirus mutates because it could affect the efficacy of a vaccine.Like all living cells, viruses evolve their chemical make-up changes. In viruses like the flu, that happens frequently, which is why every year there is a new vaccine to treat whatever strain is expected to circulate. With COVID-19, however, those mutations happen much slower, according to research out of Arizona State University.“One of the things we’re still keeping an eye on is the evolution of this virus because that virus is still around in the community,” said Dr. Efrem Lim, an assistant professor at ASU. “Everyone is coming in blind to this. This is a novel virus. This isn’t something we have seen before.”In March, Arizona State University played host to our country’s fourth COVID-19 case. As soon as it was detected, Dr. Lim started studying how the virus mutates and sent his findings to the World Health Organization. It's something that still continues to this day.“This virus, overall, mutates pretty slowly, which is a good thing,” said Dr. Lim. “However, we can have instances where the virus can have very large, dramatic, mutations, such as deletions in the genome.”While rare, Dr. Lim says those mutations can be significant as it changes how the virus acts inside the body.Currently, scientists are focusing much of their efforts on identifying ways to eliminate the function of the spike protein in COVID-19, as it is the way the virus binds to our cells and infects them (spike proteins are the stalks that protrude from the center of the virus that make it so recognizable).“It is very good news that the virus is not changing rapidly,” said ASU virologist Dr. Brenda Hogue. “We will have to see over time, as the virus continues to circulate, as we put a vaccine into play, whether or not there will be any issues.”Dr. Lim says right now there does not appear to be any issues because the virus mutates slowly, but he adds it could adapt to a vaccine once one begins to circulate.He says more testing needs to be done to determine that, however. 2140

Authorities say a U.S. Navy training plane traveling from Florida has crashed in an Alabama residential neighborhood near the Gulf Coast, killing both people in the plane. Navy spokesman Zach Harrell says both people in the T-6B Texan II training plane died Friday. No injuries were reported on the ground. Foley Fire Chief Joey Darby told news outlets that responders encountered and extinguished a “large volume of fire” that had engulfed a home and cars. The crash occurred near the city of Foley and the town of Magnolia Springs. A Navy spokeswoman says the plane had flown out of Naval Air Station Whiting Field, about 30 miles northeast of Pensacola. 664

At least 100,000 small businesses have had to close permanently in the last nine months, according to data gathered by Yelp. Millions more have dealt with temporary closures and major losses in revenue.Now, many remaining small businesses are reliant on a strong holiday shopping season, and there’s finally some good news for these business owners and their employees.For example, at the Boston area small business called Boing Toy Shop, owner Kim Mitchell has been working overtime for the pasting nine months. She has had drastically change her business model.“In certain ways, I feel like although I am in the same physical footprint, I am almost running a completely different business,” said Mitchell.Since the start of the pandemic, Mitchell has had to shift more than half of her business online and added curbside pickup to keep her toy shop out of the red.“In certain ways, I almost feel like we are part store-front, part warehouse,” she added.However, in many ways, she still feels lucky to have some form of her business when so many other small businesses have had to close.“One of the first ones, unfortunately, was the store right across the street from me,” said Mitchell.The boutique clothing store across the street from Boing is just one of an estimated 27 percent of small businesses that have closed across the country, according to a Harvard University Project. And without a strong holiday season, even more permanent closures are feared.So, how has the holiday shopping season been so far for small businesses?“I had by far my most successful small business Saturday, which I did turn into small business weekend. I sort of stretched it,” said Mitchell. “There definitely is a sense, and I have a sense from my customers, that they are making a conscious decision to support their local businesses.”From Boing to stores around the country, consumers opened their wallets more than ever on Small Business Saturday. According to Adobe Analytics data, they spent a record .7 billion just online.“Smaller retailers have seen a 501 percent increase in revenue through the holiday season so far relative to a typical day in October,” said John Copeland with Adobe Analytics,” “From a percentage increase, small and medium-sized businesses are outperforming in terms of percentage gains.”From Adobe’s holiday shopping data to the Boston toy shops’ experience, it is clear consumers are conscious of how much mom and pop businesses are struggling and how important it is to help them and the workers they employ."It is really nice that, especially in a time like this, where we really need the community’s support in return. They are coming out and realizing that ‘hey, these small businesses have been there for us for a long time; now it is time to get their back,’” added Mitchell. 2811

At least 36 people have been confirmed dead as a result of Hurricane Michael, according to authorities.The number rose Saturday after a local medical examiner confirmed the death of a woman in Bay County, Florida, bringing the death toll in Florida alone to 26.Authorities did not offer additional details on the death. 327

ATLANTA (AP) — Marjorie Taylor Greene has won the Republican nomination for Georgia’s 14th Congressional District. She’s a businesswoman who has expressed support for the far-right conspiracy theory QAnon and been criticized for a series of racist comments. Neurosurgeon John Cowan was defeated in the primary runoff for the open seat on Tuesday. Greene's victory comes despite several GOP officials denouncing her campaign after videos surfaced in which she expresses racist, anti-Semitic and anti-Muslim views. She has responded to the criticism by blasting “the fake news media” and “the DC swamp.” Her victory comes in a deep-red area in northwest Georgia. 668

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