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BEIJING, Nov. 22 (Xinhuanet) -- Underweight patients may have more possibilities of mortality within 30 days of general and vascular surgery compared with mildly obese patients, according to a research published online in Archives of Surgery Tuesday.Researchers at the U.S. National Surgical Quality Improvement Program conducted the research for the years 2005 and 2006, and assessed the contribution of BMI (Body Mass Index) to 189,533 postsurgeries morbidity and mortality by obesity classes.They found that compared with the middle BMI quintile group, patients with BMI value below 23.1, had greater chances for death. For the highest BMI quintile group, higher mortality rate was also observed.However, the researchers also found that obesity may as well be associated with increased mortality for some individual types of surgeries."These individual types of procedures include procedures with which the general surgeon should have definite experience: colorectal resection, colostomy formation, cholecystectomy, hernia repair, mastectomy, and wound debridement," said George J. Stukenborg, PhD, of the University of Virginia inCharlottesvilleand his colleagues.Based on a 30 –day morbidity and mortality risk calculation, the sample patients were categorized into BMI quintile ranges. BMI value of less than 23.1 was considered as lowest, values from 26.3 to 29.6 considered as the middle quintile, and above 35.2 considered as the highest.Factors such as lack of enough data on nonfatal complications and hospital resources, or examining mortality over the 30-day baseline, may cause limitations and inaccuracy to the research and more studies on a wider range of patients in terms of BMI are needed to further confirm the current conclusion, researchers said.
BEIJING, Jan. 4 (Xinhua) -- Senior Chinese leader Li Changchun on Wednesday called for more efforts to strengthen the Internet construction and management and promote a healthy online culture.Li, a member of the Standing Committee of the Political Bureau of the Communist Party of China Central Committee, made the remarks at a national conference of publicity officials.Li also urged the officials to work and fortify the leading status of Marxism in the country's ideological field, and to provide spiritual support for the economic and social development.Li Changchun (C), a member of the Standing Committee of the Political Bureau of the Communist Party of China Central Committee, addresses a national conference of publicity officials in Beijing, capital of China, Jan. 4, 2012.The publicity work should help create a favorable environment for the country's efforts to stabilize economic growth, regulate commodity prices, adjust the economic structure, improve people's livelihood, carry forward reform and promote social harmony, Li said.Moreover, Li called for efforts to deepen the reform and promote development in the country's cultural sector.

WASHINGTON, Dec. 7 (Xinhua) -- The use of two drugs never tried in combination before in ovarian cancer resulted in a 70 percent destruction of cancer cells already resistant to commonly used chemotherapy agents, say researchers at Mayo Clinic in Florida.Their report, published on-line Wednesday in Gynecologic Oncology, suggests that this combination, ixabepilone and sunitinib, might offer a much needed treatment option for women with advanced ovarian cancer.Neither drug is approved for use in ovarian cancer. Ixabepilone is a chemotherapy drug that, like other taxane drugs, targets the microtubules and stops dividing cells from forming a spindle. It has been approved for use in metastatic breast cancer. Sunitinib, approved for use in kidney cancer, belongs to a class of tyrosine kinase inhibitors that stops growth signals from reaching inside cancer cells.When caught at late stages, ovarian cancer is often fatal because it progressively stops responding to the chemotherapy drugs used to treat it."Women die from ovarian cancer because their tumors become resistant to chemotherapy, so a drug that might be able to reduce that resistance -- which may be what this combination of agents is doing -- would be a boon to treatment of this difficult cancer," says study coauthor Gerardo Colon-Otero.The finding also highlights the importance of the role of a molecule, RhoB, that the researchers say is activated by the drug duo. It might be a potential biomarker that may help identify patients who might benefit from such combination therapy, the researchers say.
CAPE TOWN, Nov. 13 (Xinhua) -- The research vessel SA Agulhas has set off from Cape Town on a 10-day polar tour intended to promote dialogue on climate change, authorities confirmed on Sunday.The trip was designed to mark the 17th Climate Conference of the Parties (COP17) to be held in Durban later this month, according to the Department of Environmental Affairs.The voyage, which set off Saturday noon with scientists, academics, students and journalists aboard, would host exhibitions, symposiums and lectures from climate change scientists on the work of the polar research vessel, spokesman Zolile Nqayi said in a statement.The exhibitions and lectures would also highlight the various scientific activities undertaken by the department and its partners in Antarctica and the Southern Oceans, according to the South African Press Association (SAPA).Apart from her research and supply work, the Agulhus also helped to rescue the Magdalena Oldendorff, which became stuck in thick ice in June 2002.In December the SA Agulhas would make its final voyage to Antarctica before retirement.The Agulhas, which has been in service for 33 years, would be replaced by a new vessel under construction in Finland."She served us very well," said Dr Monde Mayekiso, deputy director general of oceans and coasts."The new vessel will have enhanced technologies and capabilities to further understand the ocean environment and to bring that understanding to an increasing number of South Africans, " he said.
WASHINGTON, Dec. 22 (Xinhua) -- The journal Science on Thursday chose the HPTN 052 clinical trial, an international HIV prevention trial as the 2011 Breakthrough of the Year.The study found that if HIV-infected heterosexual individuals begin taking anti-retroviral medicines when their immune systems are relatively healthy as opposed to delaying therapy until the disease has advanced, they are 96 percent less likely to transmit the virus to their uninfected partners. Findings from the trial, first announced in May, were published in the New England Journal of Medicine in August.The study was funded by the U.S. National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health."The HPTN 052 study convincingly demonstrated that anti- retroviral medications can not only treat but also prevent the transmission of HIV infection among heterosexual individuals," said NIAID Director Anthony Fauci in a statement. "We are pleased that Science recognized the extraordinary public health significance of these study results."Science's list of nine other ground-breaking scientific achievements from 2011 include:The Hayabusa Mission: After some near-disastrous technical difficulties and a stunningly successful recovery, Japan's Hayabusa spacecraft returned to Earth with dust from the surface of a large, S-type asteroid. This asteroid dust represented the first direct sampling of a planetary body in 35 years, and analysis of the grains confirmed that the most common meteorites found on Earth, known as ordinary chondrules, are born from these much larger, S-type asteroids.Unraveling Human Origins: Studying the genetic code of both ancient and modern human beings, researchers discovered that many humans still carry DNA variants inherited from archaic humans, such as the mysterious Denisovans in Asia and still-unidentified ancestors in Africa. One study this year revealed how archaic humans likely shaped our modern immune systems, and an analysis of Australopithecus sediba fossils in South Africa showed that the ancient hominin possessed both primitive and Homo-like traits.Capturing a Photosynthetic Protein: In vivid detail, researchers in Japan have mapped the structure of the Photosystem II, or PSII, protein that plants use to split water into hydrogen and oxygen atoms. The crystal-clear image shows off the protein's catalytic core and reveals the specific orientation of atoms within. Now, scientists have access to this catalytic structure that is essential for life on Earth -- one that may also hold the key to a powerful source of clean energy.Pristine Gas in Space: Astronomers using the Keck telescope in Hawaii to probe the faraway universe wound up discovering two clouds of hydrogen gas that seem to have maintained their original chemistry for two billion years after the big bang. Other researchers identified a star that is almost completely devoid of metals, just as the universe's earliest stars must have been, but that formed much later. The discoveries show that pockets of matter persisted unscathed amid eons of cosmic violence.
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