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Several authors of a large study that raised safety concerns about malaria drugs for coronavirus patients have retracted the report. They say independent reviewers weren't able to verify information that’s been widely questioned by other scientists. Thursday’s retraction in the journal Lancet involved a report on hydroxychloroquine and chloroquine, drugs long used for preventing or treating malaria but whose safety and effectiveness for COVID-19 are unknown.The study linked the drugs to a higher risk of death or heart problems. The study leaders also retracted an earlier report using the same company’s database on blood pressure drugs published by the New England Journal of Medicine. 700

Southwest Airlines will be making the middle seat on their planes available again for passengers beginning December 1.In a series of tweets on Twitter, the airline said “this decision was not made lightly” and “a growing body of data and research supports that face masks and enhanced cleaning, coupled with HEPA filtration, are highly effective measures to protect against the transmission of COVID-19 in air travel.” 426

SORRENTO VALLEY, Calif. (KGTV) - Another San Diego-based company is moving forward on developing a vaccine for the coronavirus. Sorrento Therapeutics is working on several projects that they believe could lead to viable vaccines or treatments. One of them was announced on Monday. Sorrento Therapeutics said it was partnering with Boston-based Smartpharm to create a gene-encoded antibody vaccine. “In the effort to more quickly resolve the global COVID-19 crisis, our company has initiated a rapidly accelerated program for the identification of potent neutralizing antibodies against SARS-CoV-2 coronavirus antigens that may be used for either treatment or prophylaxis,” said Henry Ji, CEO of Sorrento Therapeutics. Sorrento Therapeutics is also working on another vaccine called the I-Cell project. That vaccine uses a decoy virus to activate a person’s immune system to train it to attack the real virus. It’s also developing a protein called COVIDTRAP that can bind to the receptors on the coronavirus, thus blocking it from being able to bind to the receptors on healthy human cells. If proven succesful, it could be used as a treatment or preventative measure.How long will it take for them to be ready?“That all depends on what leeway the FDA gives us,” said Mark Brunswick, Senior Vice President of Regulatory Affairs at Sorrento Therapeutics. If they can get fast tracked, he estimates they can start clinical trials in 2 months, as opposed to 9-12 months normally. 1483

SHERMAN HEIGHTS, Calif. (KGTV) - A storage facility for homeless people to keep their belongings is at capacity, leading some people to call for expansion.The facility is in Sherman Heights, near 20th Street and Commercial. It opened in June of 2018 with room for 500 bins.It was full by Halloween.Now there is a 200 person waiting list. The city initially wanted to put 1000 storage bins in the warehouse, but pushback from neighbors led to a compromise of just 500.Neighbors worried that the facility would be a magnet for homeless people, drawing them to the area.Six months later, people who spoke to 10News say the opposite has happened. They still see homeless people in the area, but not any more than before the facility opened.They also say the amount of clutter on the streets and sidewalks has decreased dramatically.Crime has also gone down in the area. According to the crimemapping.com website, there were 188 crimes reported within 1500 feet of the facility in August of 2018. In December, that number had dropped to 73 (see chart above).Part of that is from extra police patrol. A recent police department report says that SDPD is spending nearly million on overtime to add patrols in the neighborhood of the facility.City officials told the San Diego Union Tribune they have no plans to expand the facility. But at a meeting last month at the University of San Diego, several homeless advocated said it's an idea worth looking into. 1460

SPRING VALLEY, Calif. (KGTV) — A man who was fatally stabbed in Spring Valley on Friday, and the woman arrested on suspicion of his murder, have been identified.Manuel Castro, 41, was found Friday just after 11:30 p.m. at his apartment in the 3500 block of James Circle, after a reported stabbing. He was rushed to the hospital with a stab wound to the chest, where he died shortly after arriving.Castro's live-in girlfriend, Anielka Arbizu, 37, was found at the scene when deputies arrived. She was taken to the hospital with non-life-threatening injuries.Sunday, Arbizu was charged with one count of murder at Las Colinas Detention and Reentry Facility.Sheriff's deputies don't suspect any other suspects in the case. 727