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LA JOLLA, Calif. (KGTV) - A researcher at UC San Diego just got a million grant to further his work into nanosponge therapy.Liangfang Zhang, a professor of nanoengineering and bioengineering, has been working on creating macrophage cellular nanosponges, tiny particles covered in white blood cell membranes, to treat sepsis and other diseases."They can be used to bind to the virus and neutralize the virus," Zhang says. "So now the virus would lose the ability to infect the host cells."The nanosponges act as decoys, tricking a disease or virus into binding with them instead of with human cells. While the initial aim is to treat sepsis, Zhang says it has applications to other deadly diseases, including COVID-19."The formulation that we're developing for treatment of Sepsis is the same formulation that you will use with COVID-19," he says.The grant comes from CARB-X, a Boston-based medical philanthropy that specializes in funding research into antibacterial treatments. Zhang says the money will be used for his company, Cellics Therapeutics, to further advance the research into clinical trials, FDA approval, and production of the nanosponge therapy.Steve Chen, president and chief medical officer of Cellics Therapeutics, says he's hopeful they can advance the nanosponges into human trials within two years."We're essentially looking at how this platform can treat not just infectious disease or future pandemics, but you could actually have a lot of applications in any type of autoimmune diseases or any type of inflammatory diseases," says Chen.In an early study published this year, Zhang's research showed the nanosponges were around 90% effective at blocking infections from taking hold.RELATED: UC San Diego researchers testing nanosponges to fight COVID-19Chen says the research and trial period may take too long for the nanosponges to be used during the current coronavirus pandemic. But he's hopeful it will help make the next outbreak less severe."My sincere desire is that we are not going to need this for COVID-19. But I think this does position us very well for any potential future kind of viral outbreak," says Chen.Cellics is also working on a Red Blood Cell version of their nanosponges, which may be ready for human trials within a year. 2283
JULIAN, Calif., (KGTV)— Firefighters in Julian are hoping to keep San Diego’s last volunteer fire department alive, despite being voted to shut down last week. The Julian Cuyamaca Fire Protection District is now suing the County, alleging the decision to dissolve the department was made in secret meetings. The court hearing for Wednesday was postponed in Downtown San Diego after a judge recused himself from the case.Two weeks ago, Debbie Mushet voted to have the county take over the Julian Cuyamaca Fire Protection District [JCFPD]. “I definitely voted yes for it, and I thought that was the end of it,” Mushet said. In this special election, 56% of Julian residents voted to have the San Diego County Fire overtake the historic volunteer department. “It’s worked as long as I’ve been up here, but it doesn’t work anymore. There’s a time when things just need to change,” Mushet said. “The volunteers have done a great job ion the past, but it’s just the money wasn’t going to be there.”Despite losing the special election and a unanimous vote by the Local Agency Formation Commission to officially dissolve the department, volunteer firemen are not ready to give up. Attorney Cory Briggs, who represents JCFPD said that decision was made through secret meetings. Therefore, the election results and the commission votes are “null and void.” When the County transition team came to the station on Monday, protestors staged a sit-in, refusing the leave the premises. JCFPD said in a statement, the County sent armed Sheriffs Deputies to “intimidate the unarmed JCFPD personnel who were peaceful truing to secure their facilities and equipment while the new lawsuit works its way through the courts.”“CalFire and the Julian Fire Department that exists now, I don’t understand why we can’t coexist,” Debbie Hickey said. “Every time it’s been really good response times. They knew right where to come.”For years, Hickey has relied on the Julian Fire Department for emergency care for her ill husband. She said she trusts the locals more than an outsider who would be assigned to cover the Julian area. “If I was to call 9-1-1, I don’t know who will come, I don’t know what the response time will be, and that’s a very scary situation to be in,” Hickey said. “My husband is staying down in the city during this time because quite frankly, I’m scared to death to let him come home to Julian.”A volunteer fireman told 10News off camera that since Monday they have not been allowed to respond to emergency incidents. In fact, they said their radios were disconnected. In the meantime, all 9-1-1 calls are being handled by Cal-Fire Station 50, down the street from the JCFPD station.While there is no official sit-in happening now, there are still many volunteers at the station. Volunteer crews have barricaded their engines inside the garage with their SUV’s, to try to stop the county from towing their vehicles. Either way, Mushet said this back and forth is getting out of control. “Let the vote speak for itself, let the count come in, volunteers step back, and it’s over and done,” Mushet said. “This is ridiculous. They asked for the vote they got their vote, and they were not happy with the decision, so they’re refusing to give in and it’s just sad. I’ve never seen this town so divided.”Wednesday’s court hearing scheduled for 8:30 a.m. was delayed after the assigned judge recused himself from the case. No reason was given for his recusal. The hearing was postponed until next Wednesday, April 17, 2019. 3522

Kicker Landon White left the Eastern Kentucky University football team while taking a big shot at the program on his way out of the locker room.The Madison Central grad grew disgusted with what he said have been poor, or even nonexistent, safety measures as it relates to the team and its handling of player safety during the COVID-19 pandemic.White claimed in an Instagram post that no one on the team has been tested since July 6. He said symptomatic players are practicing with the team and that positive test results are not being reported.He also accused head coach Walt Wells of being more concerned about the 0,000 payout for playing West Virginia than he is about player safety.LEX 18 has attempted to contact White, but so far has not heard back.Matt Roan, Director of Athletics at Eastern Kentucky University, said in a statement that "egregiously or willfully ignoring safety guidelines, or our established protocol by any of our athletic programs, staff or students is a serious issue and will not be tolerated."Read the full statement below: 1065
JAMUL, Calif. (KGTV) - A Jamul woman whose home was destroyed by the Valley Fire is grateful for the "miracle" just feet from her burned house.Around 4 p.m. Saturday, single mom Kimberlee Jones was with her kids, ages 5 and 3, inside their home on Bunny Drive when she smelled the smoke."The plume was huge, black and brown. The wind was carrying it over the house and I knew we were in big trouble," said Jones.She saw the towering flames a few miles away, as sirens began blaring on her street.RELATED COVERAGEVALLEY FIRE: Resources on where to get help, air quality, and animal sheltersINTERACTIVE MAP: Valley Fire erupts in Japatul Valley areaPhotos: Valley Fire erupts in East County“They’ve asked to make sure that I pin them. And you can buy a new uniform, yeah, but you’d like to wear the one you wore,” he said, holding back tears."The flames seemed like they were walking as they went from one bush to the next. I screamed, ran inside, and grabbed my kids," said a tearful Jones.With no time to take anything, Jones put her kids and their dog in the truck, drove off, and got to safety. About an hour later, she and a friend tried to go back with a trailer for her horses, 11 of them in several outside paddocks. A few miles from her home, she was turned away by deputies. She took a photo of the raging flames, which had moved past her property. She didn't know the fate of home and horses."I just kept praying things would be okay. From the direction of the fire and the winds, I knew we probably would not have a home to go home to," said Jones.A day later, the fears about her home were confirmed. Animal rescue crews, which included a neighbor, snapped a photo of her home of five years, burned to the foundation.RELATED COVERAGE:Red Cross evacuation sites provide outdoor shelter and hotel lodging amid pandemicABC 10News forecast for San Diego County"Felt devastated. There's nothing left," said Jones.But near the ashes, about 50 feet away and not far from some burned fences, a rescuer made a remarkable discovery: The horses were in their paddocks, alive."It's a miracle all of my horses made it out and no worse for wear," said Jones.Jones is now bracing herself for the long road to recovery. She says she will always be grateful."The things I could never replace are alive and well. It's incredible we're all okay," said Jones.A GoFundMe campaign has been set up to help the Jones family with their recovery. 2439
KANSAS CITY, Kan. — John Schooley arrived in Wyandotte County Court wearing a black and white jail jump suit.It was a sharp contrast to his Schlitterbahn co-defendant Jeff Henry, who appeared in the same courtroom last week wearing a suit and tie.Schooley and Henry are the designers of the Verrückt water slide.The men are accused of being reckless in their design, and of knowing the slide was dangerous.Ten-year-old Caleb Schwab died on the water slide in 2016.Kansas City, Missouri, Attorney Justin Johnston argued Schooley's bond should be reduced from 0,000 to 0,000.He argued Schooley willingly turned himself in after arriving in Dallas from a business trip in China and isn't a flight risk.Johnston also said Schooley's wife and adult children live in the U.S., he has property in Texas and Alabama and retired from the Verrückt project in April 2015 with HSC Construction.Johnston also said he had letters of support for Schooley from people in the amusement park construction industryBut Wyandotte County Judge Robert Burns ruled against reducing the bond.Judge Burns said the bond was appropriate for the serious charges against Schooley and noted Schooley doesn't have any ties to the Kansas City metro area.Judge Burns also ordered Schooley to give up his passport, which he volunteered to do.As part of the bond, Schooley can't violate any laws.After the hearing, Johnston and Assistant Attorney General Adam Zentner declined comment on the bond ruling. 1517
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