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Immunotherapy has gained ground against a stubborn opponent: ovarian cancer. A personalized cancer vaccine is safe and may lengthen the lives of ovarian cancer patients, a small clinical trial found.The research, published Wednesday in the journal Science Translational Medicine, showed "significantly higher" overall survival at two years among patients who received the vaccine, compared with patients who did not.Ovarian cancer is a "silent killer" because often it goes unnoticed until it is diagnosed at a late stage. Treated with surgery followed by chemotherapy, most patients -- 85% -- relapse and ultimately develop resistance to the chemo. At this point, they run out of treatment options.Still, scientists are hopeful based on the fact that a subset of patients shows an immune response to their cancer. Generally, these patients have better survival rates than those whose immune systems don't react in the same way.A vaccine, then, might be able to trigger and boost the immune system and increase the survival rates of patients, said Dr. Lana Kandalaft, senior author of the new study and an adjunct assistant professor at the University of Pennsylvania Perelman School of Medicine.  1210

House Speaker Paul Ryan called allegations leveled against Alabama Republican Senate candidate Roy Moore about pursuing relationships with teenage girls and committing sexual assault "credible" and that he should step aside."He should step aside," Ryan told CNN Tuesday morning. "Number one, these allegations are credible. Number two, if he cares about the values that he claims to care about, then he should step aside."Ryan becomes the latest high-profile Republican voice to call on Moore to step aside, following more than two dozen Republican senators, including some of whom have suggested voting to expel Moore from the Senate should he win the December 12 special election.The flood of condemnation and calls to step down replaced what had been days of heavily caveated statements defined by senators calling for Moore to step aside "if" the allegations "were true." Starting Monday with Ryan's counterpart, Senate Majority Leader Mitch McConnell, the tone from national Republicans shifted dramatically.An Alabama woman alleged Monday that Moore sexually assaulted her when she was a teenager. Moore called the accusation "absolutely false" in a statement in Gallant, Alabama, later Monday, denying that he knew the woman.The accusations came after The Washington Post published a report last week based on interviews with more than 30 people, saying Moore pursued relationships with teenagers while he was in his 30s. One woman said she was 14 years old when Moore initiated sexual contact with her. Moore also denied those allegations and has threatened to sue the Post.For now, GOP leaders are stuck in an increasingly difficult position. Moore has repeatedly said he has no intention of stepping down and views the stories themselves -- and the GOP senators that have condemned him in its wake -- are nothing but political attacks. Senate Republicans made clear they are weighing several options on how to go forward, ranging from pushing for a write-in campaign to trying to vote Moore out of the Senate should he win.One Republican senator, Jeff Flake, the Arizonan who announced last month he would retire at the end of his term, became the first to present another choice Monday night: support Moore's opponent."If the choice is between Roy Moore and a Democrat, a Democrat no doubt," Flake told reporters.  2338

I just found out the @USPS is sending this postcard to every household and PO Box in the nation. For states like Colorado where we send ballots to all voters, the information is not just confusing, it’s WRONG. (Thread) pic.twitter.com/RoTTeJRJVl— Jena Griswold (@JenaGriswold) September 12, 2020 303

In a meeting that lasted less than 60 seconds, a Georgia board of elections voted down a plan Friday to close seven of a majority-black county's nine polling places ahead of November's midterm elections.Critics had said the plan to consolidate polling places in Randolph County, Georgia, was a brazen attempt to suppress the black vote in Georgia's governor race, which pits former Georgia House minority leader Stacey Abrams, who is black, against Georgia Secretary of State Brian Kemp, who is white.The vote came amid widespread national criticism and days after the county terminated its contract with Mike Malone, the consultant who made the recommendation. Malone had argued that closing the polling stations would save the county money, and that some of the sites suggested for closure did not comply with the Americans with Disabilities Act. 856

If you were confused, no worries!Convention rules require roll call & nominations for every candidate that passes the delegate threshold.I was asked to 2nd the nom for Sen. Sanders for roll call.I extend my deepest congratulations to @JoeBiden - let’s go win in November. ???? https://t.co/uI92P3UfLn— Alexandria Ocasio-Cortez (@AOC) August 19, 2020 361