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SAN FRANCISCO, July 28 (Xinhua) -- Amazon announced Thursday that it had reached an agreement with NBC Universal to allow its members to view certain movies from Universal Pictures on-line through its movie streaming service.According to the on-line retail giant, Oscar-winning movies such as "Eternal Sunshine of the Spotless Mind," "Gosford Park" and "Elizabeth" as well as other favorites like "Notting Hill" and "Billy Elliot" are part of the pact.The movies will be available to Amazon Prime members through its streaming service Prime Instant Video. Amazon Prime is a membership program that gives subscribers discounts on shipping for a 79 U.S. dollar annual fee.In February, Amazon said it would offer Prime customers unlimited access to an on-line video library. Last Wednesday, Amazon announced an accord with CBS that expanded the video library to more than 8,000 movies and TV shows. It said Thursday that the NBC deal will bring the number to more than 9,000.With the CBS, NBC Universal deals, Amazon steps up its rivalry against other movie streaming services, especially Netflix, a popular on-line and mail-order movie rental company which just boosted prices by 60 percent for some subscribers. Analysts said Amazon is trying to make the pitch to those customers who are disappointed with Netflix.In a second-quarter earnings letter to investors distributed on Monday, Netflix CEO Reed Hastings said Netflix had more than 24.6 million subscribers in the U.S. at the end of June and vastly more streaming content than its competitors."We haven't detected an impact on our business from Amazon Prime," he noted.
LOS ANGELES, July 18 (Xinhua) -- At least 70 genetic mutations may be involved in the formation of colon cancer, far more than scientists previously thought, a new study suggests.The study by researchers at University of Texas (UT) Southwestern Medical Center contradicts previous thinking that only a few mutated genes may play a role in the development of colon cancer."The ways we've been treating patients up to now is to just go after one target when we should be going after three to four different pathways simultaneously," said Dr. Jerry W. Shay, vice chairman and professor of cell biology at UT Southwestern.The new study identified 65 candidate genes and at least five passenger genes whose mutations play significant roles in cancer development. Inactivating the function of any of these tumor- suppressing genes led to a key step in cancer development called anchorage-independent growth, meaning cells piled up on top of each other rather than aligning neatly.According to previous studies, there were 151 candidate genes and that mutations in just eight to 15 of them would lead to cancer. There were 700 other genes classified as passenger genes whose mutations were incidental to cancer growth.Current cancer treatments target just one or two known cancer- driver genes. While patients may get transient tumor burden reduction, almost universally tumor growth returns."Those numbers are dead wrong," Dr. Shay said, suggesting a new approach to colon cancer treatments targeting multiple genes and pathways simultaneously.The next step is further research to classify more accurately which genes drive cancer and which are merely passengers, the researchers said.Study findings were published in the July 2011 Cancer Research (Priority Reports).
BEIJING, Sept. 25 (Xinhua) -- As China's economy has soared to the second place in the world, the country's scientific strength has also surged -- if only measured by the numbers.Chinese researchers published more than 1.2 million papers from 2006 to 2010 -- second only to the United States but well ahead of Britain, Germany and Japan, according to data recently published by Elsevier, a leading international scientific publisher and data provider. This figure represents a 14 percent increase over the period from 2005 to 2009.The number of published academic papers in science and technology is often seen as a gauge of national scientific prowess.But these impressive numbers mask an uncomfortable fact: most of these papers are of low quality or have little impact. Citation per article (CPA) measures the quality and impact of papers. China's CPA is 1.47, the lowest figure among the top 20 publishing countries, according to Elsevier's Scopus citation database.China's CPA dropped from 1.72 for the period from 2005 to 2009, and is now below emerging countries such as India and Brazil. Among papers lead-authored by Chinese researchers, most citations were by domestic peers and, in many cases, were self-citations."While quantity is an important indicator because it gives a sense of scientific capacity and the overall level of scientific activity in any particular field, citations are the primary indicator of overall scientific impact," said Daniel Calto, Director of SciVal Solutions at Elsevier North America.Calto attributed China's low CPA to a "dilution effect.""When the rise in the number of publications is so rapid, as it has been in China -- increasing quantity does not necessarily imply an overall increase in quality," said Calto.He noted the same pattern in a variety of rapidly emerging research countries such as India, Brazil, and earlier in places like the Republic of Korea."Chinese researchers are too obsessed with SCI (Science Citation Index), churning out too many articles of low quality," said Mu Rongping, Director-General of the Institute of Policy and Management at the Chinese Academy of Sciences, China's major think tank.SCI is one of the databases used by Chinese researchers to look-up their citation performance. The alternative, Scopus, provides a wider coverage worldwide."Chinese researchers from a wide range of areas and institutions are vying for publication, as it is a key criterion for academic appraisal in China, if not the only one. As a result, the growth of quality pales in comparison to that of quantity," said Mu, an expert on China's national science policy and competitiveness.On the other hand, China also falls behind the United States in multidisciplinary research, which is a core engine for scientific advance and research excellence.From 2006 to 2010, China published 1,229,706 papers while the United States churned out 2,082,733. According to a new metric introduced by Elsevier's Spotlight research assessment solution, China generated 885 competencies while the United States had 1,817.In other words, China's total research output is more than half that of the United States, while the number of competencies showing China's strength in multidisciplinary research is less than half that of the United States.Cong Cao, an expert on China's science and technology, put it more bluntly in an article he wrote: "When the paper bubble bursts, which will happen sooner or later, one may find that the real situation of scientific research in China probably is not that rosy."China has been investing heavily in scientific research and technological development in recent years to strengthen its innovative capacity, The proportion of GDP spent on R&D grew from 0.9 percent in 2000 to 1.4 percent in 2007, according to the World Bank.An IMF forecast in 2010 says China now ranks second globally in R&D spending. The IMF calculates China's R&D expenditure at 150 billion U.S. dollars when based on Purchasing Power Parity, a widely used economic concept that attempts to equalize differences in standard of living among countries.By this measure, China surpassed Japan in R&D spending in 2010.Many see China's huge investment in R&D as the momentum behind the country's explosive increase in research papers."Getting published is, in some ways, an improvement over being unable to get published," Mu said. "But the problem is, if the papers continue to be of low quality for a long time, it will be a waste of resources."In China, academic papers play a central role in the academic appraisal system, which is closely related to degrees and job promotions.While acknowledging the importance of academic papers in research, Mu believes a more balanced appraisal system should be adopted. "This is a problem with science management. If we put too much focus on the quantity of research papers, we leave the job of appraisal to journal editors."In China, the avid pursuit of publishing sometimes gives rise to scientific fraud. In the most high-profile case in recent years, two lecturers from central China's Jinggangshan University were sacked in 2010 after a journal that published their work admitted 70 papers they wrote over two years had been falsified."This is one of the worst cases. These unethical people not only deceived people to further their academic reputations, they also led academic research on the wrong path, which is a waste of resources," Mu said.A study done by researchers at Wuhan University in 2010 says more than 100 million U.S. dollars changes hands in China every year for ghost-written academic papers. The market in buying and selling scientific papers has grown five-fold in the past three years.The study says Chinese academics and students often buy and sell scientific papers to swell publication lists and many of the purported authors never write the papers they sign. Some master's or doctoral students are making a living by churning out papers for others. Others mass-produce scientific papers in order to get monetary rewards from their institutions.A 2009 survey by the China Association for Science and Technology (CAST) of 30,078 people doing science-related work shows that nearly one-third of respondents attributed fraud to the current system that evaluates researchers' academic performance largely on the basis of how many papers they write and publish.Despite rampant fraud, China will continue to inject huge money into science. According to the latest national science guideline, which was issued in 2006 by the State Council, the investment in R&D will account for 2.5 percent of GDP in 2020."If China achieves its stated goal of investing 2.5 percent of its GDP in R&D in 2020, and sustains its very fast economic growth over the next decade, it would quite likely pass the U.S. in terms of total R&D investment sometime in the late 2010s," said Calto, adding that it is also quite likely that at some point China will churn out more papers than the United States.According to Calto, China does mostly applied research, which helps drive manufacturing and economic growth, while basic research only accounts for 6 percent, compared with about 35 percent in Germany, Britain, and the United States, and 16 percent in Japan."In the long term, in order to really achieve dominance in any scientific area, I think it will be necessary to put significant financial resources into fundamental basic research -- these are the theoretical areas that can drive the highest level of innovation," Calto said.
MANILA, June 14 (Xinhua) -- At least 200 people, mostly children, have been taken to hospitals after allegedly suffering from food poisoning at a birthday party in the northern Philippine province of Bulacan, local newspaper Manila Bulletin reported Tuesday.Most of the victims suffered from stomach and chest pains, diarrhea and vomiting, local health officer Dr. Rizalli Lucas was quoted as saying.The victims claimed the cause of their food poisoning was the spaghetti served during a birthday celebration over the weekend in a village of Calumpit town.James P. de Jesus, mayor of Calumpit, said the situation is now contained and controlled but they still have to implement health measures and to determine the cause of the alleged food poisoning.Police have started investigating the incident.