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Pfizer announced Monday that its COVID-19 vaccine candidate has been 90% effective.In a press release, the company said that in Phase 3 trials, the vaccine has proven to promote a vaccine efficacy rate above 90% following the two-shot regimen.The Associated Press said that while Pfizer's announcement means the company is on track to file an application for emergency use authorization later this month, it does not mean a vaccine is "imminent" and more studies are needed.Pfizer's vaccine candidate began Phase 3 testing in the summer and is among a handful of vaccine candidates that could be distributed in the coming months pending FDA approval.Phase 3 trials consist of testing about 30,000 voluntary participants in a double-blind study — meaning half of those participating receive the vaccine, and half receive a placebo. Pfizer's vaccine requires two shots, which need to be taken 28 days apart.According to Pfizer, 90% of those who were tested for the vaccine had developed protection against the virus seven days following the second shot.Pfizer is already in the process of producing millions of doses of its vaccine candidate after the U.S. government agreed to pay .95 billion for 100 million doses of the vaccine, should it prove effective. If and when the FDA grants approval for the vaccine, it will be distributed to hospitals around the country by the U.S. military in an effort the Trump administration has dubbed "Operation Warp Speed.Even though hundreds of thousands of doses of the Pfizer vaccine will be ready for shipment if it is approved for emergency use, it will need to be rationed in the first months of its availability. According to a playbook for "Operation Warp Speed," essential health care workers and people in high-risk populations would have the first opportunity to get a COVID-19 vaccine. The rest of the general public will be able to get the vaccine as more doses become available later in 2021.Pfizer was one of a handful of companies that pledged in September not to distribute their vaccine under political pressure, and would only do so if it proved to be effective in large scale trials.Monday's announcement sent stock market futures through the roof, as investors eyed a return to economic normalcy should Pfizer's vaccine be given emergency approval in the coming days or weeks.President Donald Trump also celebrated the announcement in a tweet on Monday morning."STOCK MARKET UP BIG, VACCINE COMING SOON. REPORT 90% EFFECTIVE. SUCH GREAT NEWS!" Trump tweeted. 2524

PATERSON, N.J. -- A tiny poodle named Bear is clinging to life after being tossed from a vehicle in New Jersey over the weekend, a local shelter said.The Ramapo-Bergen Animal Refuge described the dog as emaciated and matted when he was found lying in the street "after being discarded like trash," the shelter wrote on Facebook. It appears he suffered "a lifetime of neglect," they wrote.The dog was thrown from a car window around 1:30 p.m. Saturday, near 927 Market St. in Paterson, the social media post said.As of Sunday morning, the poodle was in the intensive care unit at Oradell Animal Hospital in Paramus.The shelter said Bear suffered pelvic fractures, skin lesions from road rash and a possible herniated diaphragm. Doctors suspect a skull fracture, but the dog was not yet stable enough for a CT scan to confirm.The Facebook post said a day or so would be needed to determine the poodle's long-term prognosis.The shelter and authorities are now hoping someone might come forward with information that helps them find the person responsible for the animal abuse.Anyone with information is asked to contact Detective Richard Martinez at 973-881-3640.This story was originally published by Mark Sundstrom at WPIX. 1230

PALM HARBOR, Fla. — Four Florida siblings were on a mission to bring their dad home. Scott Piwinski has terminal throat cancer and the community came together to grant his final wish. Quadruplets Nick, Danielle, Rachael and Sarah Piwinski were preparing to spend their last Thanksgiving with their dad.“My dad. He means everything to me,” Nick said.“It definitely has been a struggle. I’m grateful for my siblings,” Danielle chimed in.Together, the 21-year-old siblings worked to complete their dad’s final wish — to spend his remaining days in his own home.“For him to come home one last time and spend it with us — for hours, days or weeks — is going to be incredible,” Rachael said while wiping away tears. But two years fighting terminal throat cancer took a toll on Scott and his Palm Harbor, Florida home. From a hole in the roof to stained carpet, the home was in need of some TLC. “The entire house was not in any shape for him to come home to,” Danielle said.So the siblings put out a call to the community and Scott’s Coast Guard family, where he served as a chief for more than two decades.Almost immediately, dozens of volunteers fixed the roof, put in new floors and prepared Scott’s bedroom for his return.“They said if we were in this situation, we know Scott would do the same,” Sarah said with a smile.Next door neighbor Melissia Delgado was one of the volunteers to chip in.“When we first moved into our Palm Harbor home, Scott had just been diagnosed with cancer," Delgado said. "He had a trach in his throat and he was outside offering to help us move furniture into our house! Which was amazing.”Even strangers like Carissa Konopack donated an entire Thanksgiving meal.“It just touched me so deeply and I really felt like I wanted to help too,” Konopack explained.The Piwinski siblings hoped to bring their dad home by Thanksgiving, but an insurance mix-up pushed back their plans. However, he did return home Friday afternoon, much to his family's delight.But they spent the Thanksgiving holiday at Suncoast Hospice.“That means the most to us," Danielle said, "that we’re all together." 2171

PASADENA, Calif. (AP) — Police in California have launched an investigation after authorities received calls of six people showing signs of drug overdoses during a six-hour period in the same city. The Pasadena Star-News reported Pasadena officials say two patients died, three recovered and one remained in a hospital receiving treatment. Authorities could not say conclusively whether the two men who died succumbed to drug overdoses until they receive a coroner’s autopsy findings. Police say they believe the cases may involve fentanyl. Pasadena police spokesman Lt. Bill Grisafe calls the suspected overdose surge an anomaly not previously seen in Pasadena. 670

Police arrested an 18-year-old man Saturday morning in the port area of Dover in connection with an attack a day earlier on a train at a London Underground station, London's Metropolitan Police said.It was a "significant arrest" as the investigation continues, Deputy Assistant Commissioner Neil Basu, the senior national coordinator for counterterrorism policing, said in a statement."This arrest will lead to more activity from our officers. For strong investigative reasons, we will not give any more details on the man we arrested at this stage," he said. 567

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