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PUEBLO, Colo. — On the afternoon of November 4, 2019, the U.S. Attorney's office announced the arrest of Richard Holzer, a white supremacist who they say had plans to bomb a Jewish synagogue in Pueblo,Colorado, about two hours south of Denver. "We are here today to announce that federal law enforcement, working in conjunction with the Pueblo Police Department, has successfully stopped what we believe to be an imminent threat of domestic terrorism against a Colorado religious institution," authorities said.Authorities say Holzer met up with three undercover FBI agents to purchase bombs in a planned attack against Temple Emanuel, the second oldest synagogue in the state.According to a criminal complaint, FBI agents had been talking with Holzer since September, tracking multiple Facebook accounts of his in which he talked to other white supremacists through private messages about attacking Jewish people. In one message, Holzer said, "I wish the Holocaust really did happen." Holzer told undercover agents he hired someone to poison the synagogue's water supply and was now preparing for a "racial holy war.""Jewish community is tiny in Pueblo," one Colorado woman said. "And we all know each other and support one another and our children."Thirty-five families are part of this small congregation. Michael Atlas-Acuna, the president of Temple Emanuel's board of directors, is still a bit shaken by the plot to blow up a synagogue that was built in 1900. "I looked at the building and the inside, and I thought, 'God, we could have lost this,' " he said.If there's a silver lining to take away from the foiled terror plot, it's that the congregation is now stronger than ever before. It was a packed house at a recent Friday night Shabbat service.The congregation called for peace and happiness, and they said they won't let what happened scare them away. "We're going to be here another 100 years," Atlas-Acuna said. "We're going to take the right precautions that we need to take in order to be safe. Maybe the reason was to wake everybody up and realize that there is that threat out there, and to bring everybody together, and I think the whole community is going to be that much more alert." If convicted, Holzer faces up to 50 years in prison. 2277

Public health officials are investigating an E. coli outbreak that has infected at least 17 people in eight states, the US Centers for Disease Control and Prevention 178

SAN DIEGO, Calif. – What’s usually a marathon for biotech companies is now a full-blown sprint to stop the spread of coronavirus.Kate Broderick, the Senior Vice President of R&D at Inovio Pharmaceuticals in San Diego, remembers the moment she first learned about the mysterious outbreak unfolding thousands of miles away. “Yes, absolutely, distinctly, probably one of those moments you’ll remember forever. I was in my kitchen at home the 31st of December,” said Broderick.She never imagined that two months later it would be the crisis it is today. “Every week I keep thinking it’s going to get better, it’s going to start to tone down a little bit, but in fact, rather than getting better it’s getting worse every week,” said Broderick.Inovio has made headlines before, creating vaccines for Zika, Ebola, and now the coronavirus. After Chinese researchers shared the genetic sequence of COVID-19, Inovio designed a vaccine in just three hours Using its proprietary DNA medicines platform technology. The vaccine was designed to precisely match the DNA sequence of the virus“In an outbreak setting we really don’t have two to three years to wait for a vaccine, so that’s where we come in at Inovio pharmaceuticals, we use DNA medicine technology,” said Broderick.While traditional vaccines use the virus itself, this method puts DNA inside E.coli, which naturally replicates the medicine over and over. The paste is then purified, leaving behind only the DNA medicine, which Inovio hopes to test in humans next month.“Infectious diseases are global and they don’t care about boundaries and borders, everyone is affected from childhood all the way through seniors,” said Phyllis Arthur, who’s been in the infectious disease industry for 20 years.Arthur is Vice President of Infectious Diseases and Diagnostic Policy at BIO, an association made up of about 1,000 companies.“One of the things we’re seeing, from outbreak to outbreak, unfortunately, is we’re getting faster at using platform technologies to build something that can be tried in humans sooner than we were the last time,” said Arthur.She’s following dozens of companies working on vaccines, treatments, and diagnostic tools. If their vaccines work, companies like Inovio will have to figure out how to manufacture them fast.“You may have the best vaccine in the world, but if you can only produce 1,000 doses of it, that’s not really going to help 1.4 billion people in China,” said Broderick. Continued funding will also be critical. Broderick says while their Zika vaccine looked promising in humans, it never ultimately got FDA approval for broad public use.“The problem there was, although great for global health, was that of course cases of the virus really steadily declined, the problem for us there was so did the funding,” said Broderick.She says that way of thinking is shortsighted but does see change on the horizon. “It’s a huge amount of responsibility on everyone’s shoulders, and I think we feel genuinely compelled to do everything in our power, hence why no one complains about two hours of sleep, because this is a point in our careers we can truly, literally, make a difference in saving lives, right now,” said Broderick.After the company begins human trials in the U.S., they’ll continue testing in China and South Korea. They hope to deliver one million doses by the end of the year.If they make it that far, it too would be a day Broderick will never forget. 3462

Talks between US President Donald Trump and North Korean dictator Kim Jong Un were cut short Thursday as a closely watched nuclear summit ended without a joint agreement signing.The White House said no deal was struck between the two leaders."No agreement was reached at this time, but their respective teams look forward to meeting in the future," press secretary Sarah Sanders wrote in a statement.The two leaders departed the Metropole Hotel, where the talks unfolded, around 1:30 p.m. local time, roughly four-and-a-half hours after the talks began.They left without participating in a working lunch and joint agreement signing ceremony that had been originally listed on the schedule.Aside from the signing ceremony, a planned lunch between the two leaders did not go forward. Instead, the White House said Trump would convene a news conference two hours earlier than planned.US and North Korean negotiators had been in Hanoi drafting language of a joint agreement ahead of the talks. Stephen Biegun, the President's North Korea envoy, arrived days before Trump to seal the document.Earlier in the day, Trump tamped down expectations he will make significant progress with Kim 1194

Social distancing has unfortunately become the new norm in the wake of the coronavirus pandemic and eating out at your favorite restaurants is no longer an option.With restaurants across the U.S. forced to close their dining rooms due to COVID-19 concerns, many are relying on carryout and delivery orders to retain a steady revenue.Fortunately, many national chain restaurants are showing their support for their community by offering free delivery services. Here are a few:Bob Evans: The restaurant 513