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BALTIMORE — Baltimore City Fire officials are investigating a Wednesday morning explosion at the BGE office building downtown.In total, 23 people were rescued from various parts of the building.Fire officials say 21 of them have been taken to the hospital. At least nine are in serious or critical condition.According to a statement, BGE said the 21 contractors were treated at area hospitals for non-life-threatening injuries.BGE said two individuals rescued were window washers who became trapped high atop a scaffold on the side of the building. Severe damage has been reported from the tenth floor of the building all the way up to the roof, which partially collapsed. 680

As mixed messages continue regarding face coverings, Mississippi became the first state to lift a statewide mask mandate. Cities and towns can now put their own rules in place.The governor said the facts and data still show masks work, and the state is still requiring them at certain events, including the state fair that starts this week.“I suspect Mississippi will see an increase in cases if people stop wearing face coverings,” said Dr. Amesh Adalja with the Johns Hopkins University Center for Health Security.Infectious disease experts remind people just because an order may be lifted, doesn't mean they should stop wearing masks.“We have to have an effective vaccine to prevent people from getting infected as well as prevent them from getting severe disease, that we had adequate testing capacity so people could know their status and wouldn't go out into public if they were positive,” said Adalja. “I think short of that, masks are going to be one tool that we have to continue to use and many people are going to get accustomed to masks and they're going to realize that masks also likely have some impact on other respiratory viruses, so we may see mask wearing much more common in the United States, similar to what it is in other Asian countries, because of the value people are gaining from them.”New research on homemade cloth masks found they expel invisible cotton fibers into the air. It’s unknown if those fibers can carry infectious viral particles, which drives home the point of washing any cloth facial coverings. Make sure you do that regularly. 1580

At least 285 U.S. children have developed a serious inflammatory condition linked to the coronavirus and while most recovered, the potential for long-term or permanent damage is unknown, two new studies suggest.The papers, published online Monday in the New England Journal of Medicine, provide the fullest report yet on the condition.The condition is known as multisystem inflammatory syndrome in children. It is considered uncommon and deaths are rare; six children died among the 285 in the new studies.Including cases in Europe, where it was first reported, about 1,000 children worldwide have been affected, a journal editorial said.The federal Centers for Disease Control and Prevention’s case definition includes current or recent COVID-19 infection or exposure to the virus; a fever of at least 100.4 for at least 24 hours; severe illness requiring hospitalization; inflammatory markers in blood tests, and evidence of problems affecting at least two organs that could include the heart, kidneys, lungs, skin or other nervous system.Digestive symptoms including nausea and diarrhea are common. Some children may have symptoms resembling Kawasaki disease, a rare condition in children that can cause swelling and heart problems.At least 35 states have had cases, and they seem to crop up a few weeks after local COVID-19 activity peaks, said Dr. Adrienne Randolph of Boston Children’s Hospital. She is a lead researcher for a multistate study that includes CDC scientists. The second paper involved 99 children in New York state, where the first U.S. cases occurred.Combined, the papers show 285 cases from March thru mid to late May but Randolph said additional U.S. children have been diagnosed in June.Most had current or recent COVID-19 infections but had previously been healthy.About 80% of children in the multistate study had heart-related problems, which included coronary aneurysms — a bulge in a heart artery that can be fatal.“Those need to be followed up,” Randolph said. “This is a life-threatening concern for a lot of patients.”Most affected children had no other health condition but about 30% were obese. The condition also appears to disproportionately affect Latino and Black children and boys.The average age was 8 years old. Researchers don’t know if adults can be affected.___Follow AP Medical Writer Lindsey Tanner at @LindseyTanner.___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. (hyperlink ‘support’ with this: http://bit.ly/2ptoKnW 2618

Astronomers looking at the atmosphere in neighboring Venus see something that might just be a sign of life.In a study published Monday, researchers from Cardiff University, MIT and elsewhere say they found the chemical signature of a noxious gas called phosphine.On Earth, phosphine is associated with life. It's found at the bottom of ponds, in badger guts and in penguin guano.Venus’ phosphine was observed in a narrow, temperate band within the planet’s atmospheres, where temperatures range from 30 to 200 degrees Fahrenheit. Scientists have speculated that if life exists on Venus, this layer of the atmosphere, or cloud deck, is likely the only place where it would survive, according to MIT.“This phosphine signal is perfectly positioned where others have conjectured the area could be habitable,” said the study’s co-author and EAPS Research Scientist Janusz Petkowski.Astronomers tried to figure out other, non-biological ways it could be produced and came up empty.“It’s very hard to prove a negative,” said Clara Sousa-Silva, research scientist in MIT’s Department of Earth, Atmospheric and Planetary Sciences (EAPS). “Now, astronomers will think of all the ways to justify phosphine without life, and I welcome that. Please do, because we are at the end of our possibilities to show abiotic processes that can make phosphine.”Outside experts — and the study authors themselves — say the research is tantalizing but not yet convincing. 1454

As the Summer of COVID draws to a close, many experts fear an even bleaker fall and suggest that American families should start planning for Thanksgiving by Zoom.Because of the many uncertainties, public health scientists say it’s easier to forecast the weather on Thanksgiving Day than to predict how the U.S. coronavirus crisis will play out this autumn. But school reopenings, holiday travel and more indoor activity because of colder weather could all separately increase transmission of the virus and combine in ways that could multiply the threat, they say.Here’s one way it could go: As more schools open for in-person instruction and more college students return to campuses, small clusters of cases could widen into outbreaks in late September. Public fatigue over mask rules and other restrictions could stymie efforts to slow these infections.A few weeks later, widening outbreaks could start to strain hospitals. If a bad flu season peaks in October, as happened in 2009, the pressure on the health care system could result in higher daily death tolls from the coronavirus. Dr. Robert Redfield, director of the Centers for Disease Control and Prevention, has said that scenario is his biggest fear.One certainty is that the virus will still be around, said Jarad Niemi, a disease-modeling expert at Iowa State University.“We will not have a vaccine yet and we will not have enough infected individuals for herd immunity to be helpful,” Niemi said.Fall may feel like a roller coaster of stop-and-start restrictions, as communities react to climbing hospital cases, said University of Texas disease modeler Lauren Ancel Meyers. Everyone should get a flu shot, she said, because if flu spreads widely, hospitals will begin to buckle and “that will compound the threat of COVID.”“The decisions we make today will fundamentally impact the safety and feasibility of what we can do next month and by Thanksgiving,” Meyers said.The virus is blamed for over 180,000 deaths and 6 million confirmed infections in the U.S. Worldwide, the death toll is put at almost 850,000, with over 25 million cases.The U.S. is recording on average about 900 deaths a day from COVID-19, and newly confirmed infections per day are running at about 42,000, down from their peak in mid-July, when cases were topping out at over 70,000.Around the country, a chicken processing plant in California will close this week for deep cleaning after nearly 400 workers got sick, including eight who died. And college campuses have been hit by outbreaks involving hundreds of students, blamed in some cases on too much partying. Schools including the University of North Carolina, Michigan State and Notre Dame have moved instruction online because of clusters on their campuses.Several vaccines are in advanced testing, and researchers hope to have results later this year. But even if a vaccine is declared safe and effective by year’s end, as some expect, there won’t be enough for everyone who wants it right away.Several companies are developing rapid, at-home tests, which conceivably could be used by families before a Thanksgiving gathering, but none has yet won approval.More than 90 million adults are over 65 or have health problems, putting them in higher danger of severe consequences if they get sick with the coronavirus. Many of them and their families are starting to decide whether to book holiday flights.Cassie Docking, 44, an urgent care nurse in Seattle, is telling her parents — both cancer survivors — that Thanksgiving will be by FaceTime only.“We all want to get to 2021,” she said, “and if that’s what it takes, that’s what we’ll do.”Caitlin Joyce’s family is forging ahead with a holiday feast. They plan to set up plywood tables on sawhorses in a large garage so they can sit 6 feet apart.“We’ll be in our coats and our sweaters,” said Joyce, 30, of Edmonds, Washington, who plans to travel to her grandparents’ home in Virginia. “It will be almost like camping.”One widely cited disease model projects 2,086 U.S. deaths per day by Thanksgiving, more than double compared with today.“In our family we will not have our extended family get-together. We will stick to the nuclear family,” said Dr. Christopher Murray of the Institute for Health Metrics and Evaluation, one of the few models making a prediction for November.Uncertainty is huge in Murray’s model: Daily deaths could be as low as 1,500 by Thanksgiving or as high as 3,100. In a more optimistic scenario, daily deaths could range from 510 to 1,200 if nearly everyone wears masks. A more pessimistic scenario? From 2,700 to 6,500 daily deaths if social distancing rules continue to be lifted and are not reimposed.With all the uncertainty, most disease modelers aren’t looking that far ahead — at least officially.Jeffrey Shaman, a public health expert at Columbia University, thinks the virus will spread more easily as the weather forces people indoors: “But what level of a bump? That’s hard to say.”At Carnegie Mellon University in Pittsburgh, computer scientist Roni Rosenfeld’s team uses machine learning to project COVID-19 deaths. The team’s computer algorithm learns from patterns it finds in state and county data to improve its forecasts.A five-time winner of a CDC competition for predicting flu season activity, Rosenfeld thinks his model’s COVID-19 projections aren’t very useful beyond four weeks because of the wild card of human behavior, including that of government officials.“What happens very much depends on us,” he said. “People, myself included, don’t always behave rationally.” Presented with the same facts, “the same person might behave differently depending on how sick and tired they are of the situation.”Like other disease modelers, Rosenfeld said the virus will still be with us at Thanksgiving, readily spreading at family gatherings. While his plans may yet change, he said he is going to travel with his wife to visit their adult children. They will wear masks and keep a safe distance during the visit.___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. 6201

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