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SAN DIEGO (KGTV) - As President Donald Trump threatens to shutdown the U.S.-Mexico Border, San Diego leaders are in Mexico City to strengthen economic ties and talk binational business.Five mayors and nearly 100 elected officials, business and community leaders from San Diego and Baja California left for Mexico Sunday for the San Diego Regional Chamber of Commerce’s 14th annual Binational Delegation to Mexico City.San Diego Mayor Kevin Faulconer said the top two issues up for discussion are the continuing Mexican sewage runoff problems that impact our beaches and the free trade relationship between the U.S. and Mexico.Monday, Mexican officials said 70 percent of trade with the U.S. is by trucks, and the Mexican Government is ready to collaborate with the U.S. to ensure border safety and that trade flows efficiently.“Free trade is incredibly important to our region here in San Diego,” said Faulconer. "We have over 100,000 jobs that are dependent upon trade with Mexico.”Faulconer said the goal is to create a safe, secure and functioning border. He is also calling for the approval of the new United States-Mexico-Canada Agreement, or USMCA.The Chamber also said advancing USMCA is a key priority of this week's meeting.Monday the delegation will discuss the U.S. Mexico trade relationship, including the border, immigration and economic development. On Tuesday the delegation will discuss the U.S. Mexico water policy.Imperial Beach Mayor Serge Dedina has been pushing for the Mexican government to rebuild basic sewage infrastructure. The sewage runoff from the Tijuana River Valley flows into some of our local beaches, shutting them down for days and sometimes even months.Dedina said he hopes to come back to San Diego with new solutions to resolve the ongoing, decades-old issue.“Will be really pressing really hard with high-level officials to really move this forward so we can continue to have clean beaches,” he said Sunday.The leaders will wrap up their trip to Mexico on Wednesday. 2016

SAN DIEGO (KGTV) -- Crews quickly put out a brush fire that erupted near Interstate 15 in the Rainbow area of north San Diego County.The fire was reported in an area off I-15, near Old Hwy 395 and Rainbow Valley Boulevard, just after 1:30 p.m. Monday, according to the California Highway Patrol.According to Cal Fire San Diego, the fire burned at least one acre with a moderate rate of spread. By 2:15 p.m., crews were able to douse the blaze before it spread any further.The cause of the fire is under investigation. 525

SAN DIEGO (KGTV) -- As an active 45-year-old man who loves to surf and take adventures with his daughter, Bryce Olson was the last person his friends expected to get cancer.In 2014, a call while at work confirmed it: stage IV metastatic prostate cancer.Metastatic means the cancer has spread to other parts of the body, lymph nodes, bones or other organs.“It was just shocking and sad and I didn’t know anything about this stuff, so I just...I rolled into whatever my doctors were recommending," said Olson.He says the standard of care - surgery, chemotherapy, and the initial hormone therapy - wasn't working.“I started coming to terms with my own mortality. I didn’t even think I’d see my kid get out of elementary school and I was losing hope," said Olson.Olson says he wanted to make his final days count. The Intel employee started learning about precision medicine and eventually pursued DNA sequencing to find out exactly what was driving his disease.“I'm a believer in profiling your tumor at a molecular level and trying to understand what’s driving your unique disease, and then taking that data and then finding the right drug for the right person at the right time," said Olson.His results led him to a clinical trial in Los Angeles, where he was a perfect molecular match for the drug being tested.Four years later, Olson's precision medicine journey led him to San Diego's Epic Sciences.“We're actually going to a place where no test has gone before," said Murali Prahalad, President and CEO of Epic Sciences. "These are metastatic patients; the disease has already spread. And we’re trying to understand in the later stages of the disease when it’s far more complicated, how do you then understand which treatment is the right one.”Patients like Olson have two treatment options, chemotherapy or hormone therapy."It's very important to know which medicine is going to work," said Pascal Bamford, Chief Scientific Officer of Epic Sciences, "At the metastatic end of this disease every week, every day, every month is critically important."The company has created a blood test to make the choice easier, called the Oncotype DX AR-V7 Nucleus Detect.If the antigen AR-V7 is detected in a patient, they have built a resistance to hormone therapy, meaning chemotherapy would likely be a better treatment option.“We think it’s very groundbreaking, to say this is the first test that can tell a patient which drug to go on to extend their life," said Ryan Dittamore, Chief of Medical Innovation.Dittamore says the test helps provides certainty for doctors. Patients they've studied have almost doubled their life expectancy with the AR-V7 test.“It can mean the world, not only to patients but loved ones," said Dittamore.Olson was AR-V7 negative, meaning he could continue hormone therapy.Four months in, it's working. “I’m going to see my kid not only get out of high school but college and get married. I’m fully confident that I can do that because I’m just going to keep pushing," said Olson.In December 2018 the AR-V7 test will be covered by Medicare, meaning thousands of more men will have access to it. 3150

SAN DIEGO (KGTV) -- As Santa Ana winds move out of the region, a freeze warning was issued for portions of San Diego County.The National Weather Service issued a freeze warning for the county's valleys and deserts from midnight through 10 a.m. Friday. Overnight temperatures dropped into the low 30s, with a few areas seeing temperatures in the mid- to upper 20s.The warning will affect cities including Escondido, El Cajon, San Marcos, La Mesa, Santee, and Poway.RELATED: Winter returns to Southern California mountains 528

SAN DIEGO (KGTV) - Crowds gathering at Veterans Park in Ocean Beach may face fines if they don't follow the county's public health orders.Tuesday morning, city crews put up orange mesh fencing around the park, but a few hours later, witnesses took pictures of two men cutting the fence down.Residents and business owners have been complaining for weeks about large groups gathering on Wednesday evenings gathered to watch the drum circle and hang out in the park.Mark Winkie is the president of the Ocean Beach Town Council. He didn't agree with shutting down the park, but he didn't condone tearing down the fence, either."Disappointing what happened here this morning, but it's important for people to know, as a town council, we really would like education to come first, to notify people about what they need to do when gathering here on such large quantities on a Wednesday," said Winkie.The public health orders banning gatherings of more than ten have been in place for months, but Winkie said it's possible not everyone is aware."Particularly for the drum circle, no city or county official has been out really interfacing with them, SDPD definitely came out, and I applaud their actions," said Winkie.Last week, police broke up the crowd, but did not issue citations.Councilmember Dr. Jennifer Campbell said it's time for enforcement."Everyday more San Diegans are dying, so we have to get tough and I'm telling you if this situation that happened last Wednesday night, happens this Wednesday night, there's gonna be a lot of clamp down, so they have got to stop it," Dr. Campbell said shouting.Violators could be fined up to ,000."By God, that is now the law and, therefore, the county sheriff should be out here arresting people who aren't wearing masks, who aren't distancing, and who are coming together," said Dr. Campbell.It's unclear if the city will put up a more permanent barrier or if anything will be in place by Wednesday evening. 1962