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WASHINGTON, Aug. 3 (Xinhua) -- The annual number of new HIV infections in the United States was relatively stable at approximately 50,000 new infections each year between 2006 and 2009, the Centers for Disease Control and Prevention's first multi- year estimates from its national HIV incidence surveillance find.However, HIV infections increased among young men who have sex with men (MSM) between 2006 and 2009, driven by alarming increases among young, black MSM -- the only subpopulation to experience a sustained increase during the period.According to the new estimates, there were 48,600 new HIV infections in the United States in 2006, 56,000 in 2007, 47,800 in 2008 and 48,100 in 2009. The multi-year incidence estimates allow for a reliable examination of trends over time. They reveal no statistically significant change in HIV incidence overall from 2006 to 2009, with an average of 50,000 for the four-year period. In 2009, the largest number of new infections was among white MSM (11,400), followed closely by black MSM (10,800). Hispanic MSM (6, 000) and black women (5,400) were also heavily affected.The new estimates were published Wednesday in the on-line scientific journal PLoS ONE."More than 30 years into the HIV epidemic, about 50,000 people in this country still become infected each year. Not only do men who have sex with men continue to account for most new infections, young gay and bisexual men are the only group in which infections are increasing, and this increase is particularly concerning among young African American MSM," said CDC Director Thomas Frieden. " HIV infections can be prevented. By getting tested, reducing risky behaviors, and getting treatment, people can protect themselves and their loved ones."

SYDNEY, Aug. 16 (Xinhua) -- People sitting in front of TV for hours on end could shorten their life expectancy by almost five years, according to an Australian study published on Tuesday by the British Journal of Sports Medicine.Researchers from the University of Queensland estimate that for every hour adults spend in front of TV, their life expectancy shortens by almost 22 minutes.Those who watched six hours a day lived 4.8 years less than those who don't watch TV.The study is the first in Australia to look into how TV habits affect longevity.The Australian researchers found that watching TV could have a similar negative impact on life expectancy to that of obesity, smoking and low physical activity."People don't realize how it all adds up," the study's lead author Dr. Lennert Veerman told the Australian Associated Press (AAP)."They should try not to watch too much TV and find alternative things to do, preferably things that are light activities," Veerman said.The study was based on data from the Australian Diabetes, Obesity and Lifestyle study and asked more than 11,000 people aged over 25 about their weekly TV viewing time.The study found that in 2008 Australian adults watched 9.8 billion hours of TV."These findings suggest that substantial loss of life may be associated with prolonged TV viewing time among Australian adults," the study said."TV viewing time may have adverse health consequences that rival those of lack of physical activity, obesity and smoking; every single hour of TV viewed may shorten life by as much as 22 minutes," it said."With further corroborative evidence, a public health case could be made that adults also need to limit the time spent watching TV."Australians are recommended to spend at least 30 minutes a day doing moderate-intensity physical activity to reduce an increased risk of developing cardiovascular disease.

WASHINGTON, June 16 (Xinhua) -- Cells in the human body are constantly being exposed to stress from environmental chemicals or errors in routine cellular processes. While stress can cause damage, it can also provide the stimulus for undoing the damage. New research by a team of scientists at the University of Rochester has unveiled an important new mechanism that allows cells to recognize when they are under stress and prime the DNA repair machinery to respond to the threat of damage.Their findings will be published Friday in journal Science. Cells in the human body are constantly being exposed to stress from environmental chemicals or errors in routine cellular processes. While stress can cause damage, it can also provide the stimulus for undoing the damage.The scientists, led by biologists Vera Gorbunova and Andrei Seluanov, focused on the most dangerous type of DNA damage -- double strand breaks. Unrepaired, this type of damage can lead to premature aging and cancer. They studied how oxidative stress affects efficiency of DNA repair. Oxidative stress occurs when the body is unable to neutralize the highly-reactive molecules, which are typically produced during routine cellular activities.The research team found that human cells undergoing oxidative stress synthesized more of a protein called SIRT6. By increasing SIRT6 levels, cells were able to stimulate their ability to repair double strand breaks. When the cells were treated with a drug that inactivated SIRT6, DNA repair came to a halt, thus confirming the role of SIRT6 in DNA repair. Gorbunova notes that the SIRT6 protein is structurally related to another protein, SIR2, which has been shown to extend lifespan in multiple model organisms."SIRT6 also affects DNA repair when there is no oxidative stress," explains Gorbunova. "It's just that the effect is magnified when the cells are challenged with even small amounts of oxidative stress."SIRT6 allows the cells to be economical with their resources, priming the repair enzymes only when there is damage that needs to be repaired. Thus SIRT6 may be a master regulator that coordinates stress and DNA repair activities, according to Gorbunova.

SAN FRANCISCO, Sept. 12 (Xinhua) -- Amazon.com Inc. is talking with book publishers to launch a rental subscription service for digital books, U.S. media reported on Monday.Several publishing executives said they aren't enthusiastic about the idea because it could lower the value of books and it could also strain their relationships with other retailers that sell their books, The Wall Street Journal quotes people familiar with the matter in a report.The Seattle-based company is considering a digital book library featuring old titles, which would be available to Amazon Prime subscribers, who currently pay 79 U.S. dollars a year for access to digital library of movies and TV shows and unlimited two-day shipping, said the report.Amazon would offer book publishers a substantial fee and could limit the amount of books that Amazon Prime customers could read for free every month, the report cited some sources as saying.The online retailing giant makes the popular electronic reader Kindle and is also reported to launch a color touchscreen tablet before October to compete with Apple's iPad and other devices in the increasingly crowded tablet computer market.The proposal is another sign that retailers are looking for more ways to deliver content digitally as customers increasingly read book and watch TV on personal computers, tablets and other electronic devices, said The Wall Street Journal report.

SYDNEY, July 15 (Xinhua) -- The world's first drug to increase life expectancy of people with advanced melanoma has been approved for use in Australia, local media reported on Friday.The breakthrough drug Yervoy got approval from the Therapeutics Good Association (TGA) on Friday amid hopes it could add two years to the life of people with the most lethal form of skin cancer but for whom other treatments have failed, the Australian Associated Press (AAP) said.Clearance for the drug's use in Australia follows similar approvals by the U.S. health regulator in March.Yervoy works by attacking and destroying cancer cells.Patients are hooked up to an intravenous drip once every three weeks for a total of four doses.Professor Peter Hersey, consultant immunologist to the Melanoma Institute Australia, said no other drug had improved survival rates like Yervoy."Not all patients respond to it but those who do have a good chance of living longer than they would have otherwise," Hersey told AAP.While it may improve survival rates, Yervoy can produce side effects from diarrhea and vomiting to serious blood infections and kidney failure.The average survival time for people with advanced melanoma is just six months.A global study of 676 people with melanoma found that 45 percent of patients given Yervoy were still alive after one year, according to AAP.More than 20 percent lived at least two years, with a small number managing to survive for six years.A separate study, published in June, which showed similarly improved survival rates for patients with newly diagnosed advanced melanoma, has raised hopes that Yervoy could be made more widely available.Melanoma is the fourth most common cancer in Australia, with 10, 300 people diagnosed each year.